Hotels in Santa Ana

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Top 5 hotels in Santa Ana at a glance

Comfort Inn Tegucigalpa — 3-star hotel in Altos de Miramonte. Guest rating: 9.0/10 — Wonderful.
Aparthotel Guijarros — 3.5-star hotel in Lomas del Guijarro Sur. Guest rating: 9.0/10 — Wonderful.
Clarion Hotel Real Tegucigalpa — 5-star hotel in Colonia Alameda. Guest rating: 8.8/10 — Excellent.
Cabañas de la Montaña — 3-star hotel in Tegucigalpa. Guest rating: 10/10 — Exceptional.
Hotel Alameda — 2.5-star hotel in Colonia Alameda. Guest rating: 10/10 — Exceptional.

Where to stay in Santa Ana?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santa Ana on Hotels.com. These Santa Ana hotels consistently deliver on comfort, location and traveler experience. Last updated on August 29, 2026.

A heated outdoor pool with lounge chairs and a restaurant area.

A breakfast buffet setup with various food items and beverages.

A hotel reception area with a modern design, featuring a marble reception desk, wooden paneling, and a large decorative wall with pottery.

Comfort Inn Tegucigalpa

Altos de Miramonte

CNY897

CNY1,067 total

includes taxes & fees

Sep 18 - Sep 19

Aparthotel Guijarros

Lomas del Guijarro Sur

CNY543

CNY646 total

includes taxes & fees

Sep 24 - Sep 25

A spacious, well-lit hallway with a polished marble floor, large windows with decorative ironwork, and a grand chandelier.

A modern living room with a dining area, large windows with a city view, and a flat-screen TV mounted on the wall.

A modern living room with a round table and chairs, a sofa, and large windows offering a city view.

A swimming pool with lounge chairs and a building in the background.

Clarion Hotel Real Tegucigalpa

Colonia Alameda

CNY795

CNY946 total

includes taxes & fees

Sep 26 - Sep 27

A room with two beds, a wooden bench, and a painting on the wall.

A cozy room with a wooden bench, a small table with a vase, and a painting of a tree on the brick wall.

A stone building with a small porch and outdoor seating area, surrounded by trees.

A room with a brick wall, a window, a colorful blanket, a jar with plant and flowers, and a pair of glasses.

Cabañas de la Montaña

Tegucigalpa

CNY1,235

CNY1,470 total

includes taxes & fees

Sep 26 - Sep 27

A swimming pool with lounge chairs, potted plants, and a modern building in the background.

A modern living room with a large white sofa, brown leather chairs, a round coffee table, and a large window with a view.

A hotel room with two beds, a small desk, and a mirror.

Hotel Alameda

Colonia Alameda

CNY724

CNY861 total

includes taxes & fees

Aug 30 - Aug 31

A modern lobby with a wooden ceiling, a grey sofa, blue chairs, a dining area, and a large abstract painting.

A swimming pool with lounge chairs and tables, surrounded by palm trees and a white building.

A gym with treadmills, an elliptical, and a bench.

A modern office space with a wooden desk, two chairs, a potted plant, and a decorative wall piece.

Holiday Inn Express Tegucigalpa by IHG

Florencia

CNY740

CNY961 total

includes taxes & fees

Sep 13 - Sep 14

A hotel lobby with a reception desk, seating area, and a large clock.

An outdoor pool area with a view of the pool, surrounded by wicker chairs and tables, potted plants, and a flag.

A hotel room with a bed, a red sofa, a glass coffee table, a dining area with a table and chairs, and a view of the city through large windows.

Florencia Plaza Hotel

Florencia

CNY681

CNY1,042 total

includes taxes & fees

Sep 24 - Sep 25

A courtyard with a central fountain, surrounded by outdoor seating and red umbrellas.

A hotel room with a bed, a sofa, a coffee table, and a chair.

A hotel lobby with a blue sofa, two glass vases, a Christmas tree, and a reception desk.

A lush indoor garden with various plants and a multi-story building in the background.

Hotel Humuya Inn

La Humuya

CNY474

CNY564 total

includes taxes & fees

Aug 30 - Aug 31

A rooftop infinity pool with lounge chairs and a dining area, overlooking a cityscape at dusk.

A gym with multiple cardio machines, large windows, and a city view.

A modern lobby with a reception desk, seating area, and a large abstract art piece.

A rooftop bar with a bar counter, seating area, and a city view.

Hyatt Place Tegucigalpa

Tegucigalpa

CNY959

CNY1,141 total

includes taxes & fees

Sep 17 - Sep 18

A pool area with a fountain, surrounded by colorful buildings and lush greenery.

A cozy living area with two sofas, a wooden bench, and a potted plant.

A beige sofa with two cushions and two wine glasses on a small white table.

A staircase with patterned steps, surrounded by lush greenery and potted plants.

Hotel Portal del Angel

Tegucigalpa

CNY517

CNY615 total

includes taxes & fees

Sep 26 - Sep 27

A hotel lobby with a check-in counter, a seating area, and a market sign.

A hotel lobby with a marble floor, columns, and a reception desk.

A multi-story hotel with a prominent entrance, palm trees, and a well-lit facade.

A pool area with lounge chairs and umbrellas, a bar area, and a view of the pool.

InterContinental Tegucigalpa at Multiplaza Mall by IHG

Florencia

CNY1,373

CNY1,794 total

includes taxes & fees

Sep 28 - Sep 29

A modern bar area with a central island, bar stools, and a well-stocked bar counter.

A buffet setup with multiple serving stations, each with a dome cover and a spoon.

A swimming pool with a ceiling design, a clock, and a view of the outdoors.

A hotel room with a large window, a round table with a lamp, two armchairs, and a patterned carpet.

Hotel Plaza Juan Carlos

Palmira

CNY863

CNY1,027 total

includes taxes & fees

Sep 29 - Sep 30

A modern interior with a central seating area, a staircase, and a view of the upper floor.

A hotel room with a large bed, a bedside table with a lamp, a mirror, and a view of the city through the balcony door.

A bar area with high chairs and a city view.

A spacious indoor area with a high ceiling, a seating area with a sofa and chairs, and artwork on the walls.

Minister Business Hotel

Florencia

CNY857

CNY1,020 total

includes taxes & fees

Aug 31 - Sep 1

An outdoor patio area with string lights, tables, chairs, and a central fountain.

A rectangular swimming pool with a tiled deck, surrounded by palm trees and greenery.

A spacious lobby with large windows, a bar area, and modern furniture.

A hotel with a modern facade, a prominent entrance, and surrounding greenery.

Hotel Honduras Maya

Palmira

CNY696

CNY829 total

includes taxes & fees

Aug 30 - Aug 31

A hotel lobby with a reception desk, a sofa, and a TV mounted on the wall.

A swimming pool with tiled flooring and metal chairs around it.

A hallway with a red door, patterned chairs, a table with a lamp, and framed pictures on the walls.

A spacious living room with two grey sofas, a wooden coffee table, and a vase with decorative plants.

Hotel Mac Arthur

La Leona

CNY423

CNY504 total

includes taxes & fees

Sep 26 - Sep 27

A room with a bed, a small bar area with stools, a television, and a Christmas tree.

URITESS INDUSTRIAl APARTAMENTS

Santa Lucía

CNY511

CNY609 total

includes taxes & fees

Aug 30 - Aug 31

A buffet with various food items including bread, pastries, and fruits.

A gym with treadmills, a mirrored wall, and a pool area.

A hotel room with a large bed, a dresser, a desk, and a view of the city.

A hallway with wooden doors, wall sconces, and a ceiling light.

Hotel Plaza San Martin

Palmira

CNY818

CNY973 total

includes taxes & fees

Sep 11 - Sep 12

A two-story building with a red-tiled roof and a covered porch.

A covered outdoor area with a tiled floor, potted plants, and a hammock.

A neatly made bed with patterned bedding, a wooden headboard, and two bedside tables with decorative items.

A spacious kitchen with a dining area, large windows, and a tiled floor.

Uyuca Vista Family Villa

San Antonio de Oriente

CNY1,359

CNY1,698 total

includes taxes & fees

Aug 30 - Aug 31

Hotel Villas del Valle

Valle de Angeles

CNY304

CNY361 total

includes taxes & fees

Aug 31 - Sep 1

A spacious lobby with high ceilings, large windows, and a central seating area with sofas and a coffee table.

A restaurant with glass tables and chairs, a tiled floor, and potted plants by the windows.

A living room with leather sofas, a glass coffee table, and decorative plants.

A multi-story hotel with a green facade, a central entrance with a decorative arch, and several balconies.

Hotel El Picacho

Tegucigalpa

CNY545

CNY649 total

includes taxes & fees

Aug 30 - Aug 31

View all properties

Go beyond your typical stay in Santa Ana

Pet friendly

Pool

Family friendly

Spa

Check out reviews of Santa Ana hotels guests love

Florencia Plaza Hotel

10/10 Excellent

"Superb breakfast, greatest staff"

Hotel Humuya Inn

10/10 Excellent

"Excelente opción en Tegucigalpa"

Hotel Plaza San Martin

10/10 Excellent

"Todo está perfecto"

Hotel Plaza Juan Carlos

10/10 Excellent

"Grea hotel, big comfortable rooms and great breakfast!"

Hyatt Place Tegucigalpa

8/10 Good

"Excelente ubicación y en un área muy cómoda para hospedarse. Muy tranquilo. La habitación ya necesita mantenimiento, las camas malísimas, rechinaban horrible y el colchón vencido. En la ducha, el acondicionador estaba vacío y no dejaron café. El personal muy amable y el desayuno rico. Lo recomendaría."

Hotel Portal del Angel

10/10 Excellent

"Pretty clean, safe and staff are super friendly always!"

Palmira Hostel

10/10 Excellent

"Muy bonito paisaje, buena atención, bonitas habitaciones."

Hotel Alameda

10/10 Excellent

"recien remodelado"

Hotel El Picacho

10/10 Excellent

"."

Frequently asked questions

How much does a hotel room cost in Santa Ana?

You can discover great hotels in Santa Ana from CNY361 with properties to suit all budgets and needs. If you're after an affordable hotel in Santa Ana that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Santa Ana hotels?

Discover great deals on Santa Ana hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Santa Ana hotels.

Can I book Santa Ana hotels with free cancellation?

It's easy to book a refundable Santa Ana hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What accommodations do travelers recommend in Santa Ana?

Guests like Cabañas de la Montaña.

Can I book a refundable hotel in Santa Ana?

If you need the flexibility to change your plans to Santa Ana, most hotels offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Santa Ana be like during my vacation?

The warmest months in Santa Ana are usually April and March with an average temp of 72°F. January and December are the chilliest months when the average temp is 68°F. The rainiest months are May and June.

Why should I book my Santa Ana accommodation with Hotels.com?

There are plenty of reasons to book your Santa Ana travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.