Hotels in New Madrid

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Where to stay in New Madrid?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in New Madrid on Hotels.com. These New Madrid hotels consistently deliver on comfort, location and traveler experience. Last updated on August 13, 2026.

Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, WiFi (free)

Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout drapes, WiFi (free)

Super 8 By Wyndham Marston

Marston

CNY443

CNY506 total

includes taxes & fees

Aug 15 - Aug 16

Hypo-allergenic bedding available, down comforters, desk

Indoor pool, open 8 AM to 11 PM, sun loungers

Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

CNY654

CNY741 total

includes taxes & fees

Aug 23 - Aug 24

Hampton Inn Sikeston

Sikeston

CNY664

CNY751 total

includes taxes & fees

Aug 20 - Aug 21

Travel Inn Marston I-55 by Hotel O

Marston

CNY321

CNY367 total

includes taxes & fees

Aug 15 - Aug 16

Fairfield Inn & Suites by Marriott Sikeston

Sikeston

CNY681

CNY771 total

includes taxes & fees

Aug 23 - Aug 24

Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board (on request), WiFi (free)

Reelfoot Lake Inn

Tiptonville

CNY411

CNY511 total

includes taxes & fees

Aug 23 - Aug 24

Studio, 1 King Bed with Sofa bed | Hypo-allergenic bedding available, in-room safe, desk, laptop workspace

TownePlace Suites by Marriott Sikeston

Sikeston

CNY735

CNY833 total

includes taxes & fees

Aug 23 - Aug 24

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Go beyond your typical stay in New Madrid

Pet friendly

Top landmarks in New Madrid

New Madrid Historical Museum

8.2/10 (36 reviews)

The center of New Madrid is home to cultural attractions like New Madrid Historical Museum, so you might want to stop by during your stay. If you want to experience more of the culture New Madrid has to offer, head to River Ridge Winery and Hunter-Dawson State Historic Site.

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Hunter-Dawson State Historic Site

7.6/10 (13 reviews)

If seeing the sights is on your list of things to do, head to Hunter-Dawson State Historic Site— just one of the landmarks located 0.7 mi (1.1 km) from central New Madrid.

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River Ridge Winery

8.4/10 (15 reviews)

Travelers might want a tour of River Ridge Winery, just one of the places to visit, and located 0.6 mi (1 km) from central New Madrid.

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Learn more about New Madrid

New Madrid is applauded for its cultural attractions such as New Madrid Historical Museum and Hunter-Dawson State Historic Site.

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A cannon on a brick platform by a river, with a steamboat in the background.

Check out reviews of New Madrid hotels guests love

Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent

"Staff were excellent! Very personable with us!"

Hampton Inn Sikeston

8/10 Good

"Hotel was nice but unfortunately someone decided to smoke in the elevator one night which made it shut down. So, until the repair was completed, everyone one the upper floors had to take the stairs down multiple floors. Usually not that big of an issue, but we were there for a bike ride and had to carry our bikes down three floors in the morning. Thankfully the elevator was fixed by the time we got back. Not really anything the hotel or staff caused, but just repercussions from the act of one person doing something stupid! We will definitely stay here again"

Reelfoot Lake Inn

10/10 Excellent

"Clean"

Frequently asked questions

How much does a hotel room cost in New Madrid?

You can find top hotels in New Madrid from CNY367 with options to suit your budget and needs. If you're looking for an affordable hotel in New Madrid that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at New Madrid hotels?

Discover great deals on New Madrid hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on New Madrid hotels.

Can I book New Madrid hotels with free cancellation?

It's easy to book a refundable New Madrid hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What hotels do travelers like in New Madrid?

Guests like Super 8 By Wyndham Marston.

Can I book refundable accommodations in New Madrid?

If you need the flexibility to change your travel plans to New Madrid, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in New Madrid be like during my vacation?

The warmest months in New Madrid are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 42°F. The rainiest months are March and April.

Why should I book my New Madrid hotel through Hotels.com?

There are plenty of reasons to book your New Madrid travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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