Hotels in St Mary

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Where to stay in St Mary?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in St Mary on Hotels.com. These St Mary hotels consistently deliver on quality, location and traveler experience. Last updated on September 5, 2026.

Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Deluxe Studio Suite, 1 King Bed, Non Smoking | Bathroom | Hair dryer, towels

Baymont by Wyndham Chester IL

Chester

CNY631

CNY700 total

includes taxes & fees

Sep 8 - Sep 9

In-room safe, desk, blackout drapes, soundproofing

Holiday Inn Express & Suites Perryville by IHG

Perryville

CNY711

CNY814 total

includes taxes & fees

Oct 7 - Oct 8

Perryville RV Resort

Perryville

CNY446

CNY510 total

includes taxes & fees

Sep 7 - Sep 8

Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes

Super 8 by Wyndham Perryville

Perryville

CNY473

CNY542 total

includes taxes & fees

Sep 13 - Sep 14

Microtel Inn & Suites by Wyndham Sainte Genevieve

Ste Genevieve

CNY599

CNY704 total

includes taxes & fees

Oct 4 - Oct 5

New Orleans Room | WiFi (free), bed sheets

The Conner House B&B

Prairie du Rocher

CNY1,048

CNY1,164 total

includes taxes & fees

Sep 7 - Sep 8

Suite 11, 1 Queen Bed with Sofa bed, Pets Allowed | Interior

The Atrium - A Boutique Hotel

Perryville

CNY507

CNY1,071 total

includes taxes & fees

Sep 7 - Sep 8

Days Inn by Wyndham Perryville

Perryville

CNY478

CNY547 total

includes taxes & fees

Sep 13 - Sep 14

Coffee/tea maker, full-size fridge, microwave, oven

55-inch Smart TV with digital channels, TV, streaming services

Egyptian cotton sheets, premium bedding, down comforters

Urban Lofts

Perryville

CNY1,353

CNY2,087 total

includes taxes & fees

Sep 7 - Sep 8

The Mediterranean House 1858

Perryville

CNY2,312

CNY4,200 total

includes taxes & fees

Sep 7 - Sep 8

Standard room, 2 double beds. | Blackout drapes, soundproofing, iron/ironing board (on request)

Standard room , 1 King bed. | Blackout drapes, soundproofing, iron/ironing board (on request)

Triangle Inn Motel

Ste Genevieve

CNY408

CNY479 total

includes taxes & fees

Oct 4 - Oct 5

Iron/ironing board, rollaway beds (free), WiFi (free), bed sheets

Quality Inn Perryville I-55

Perryville

CNY453

CNY518 total

includes taxes & fees

Sep 13 - Sep 14

Standard Room, 1 King Bed | Desk, laptop workspace, blackout drapes, iron/ironing board

Desk, laptop workspace, blackout drapes, iron/ironing board

Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

CNY637

CNY707 total

includes taxes & fees

Oct 4 - Oct 5

Standard Room, 2 Queen Beds, Refrigerator & Microwave, Golf View | Desk, blackout drapes, iron/ironing board, rollaway beds (surcharge)

Standard Room, 1 King Bed, Jetted Tub, Golf View | Desk, blackout drapes, iron/ironing board, rollaway beds (surcharge)

Crown Pointe Lodge, BW Signature Collection

Farmington

CNY736

CNY801 total

includes taxes & fees

Sep 13 - Sep 14

Super 8 by Wyndham Farmington

Farmington

CNY399

CNY435 total

includes taxes & fees

Sep 13 - Sep 14

Standard Room, 2 Double Beds | Desk, iron/ironing board, WiFi (free), bed sheets

Madison Inn Lodge

Fredericktown

CNY587

CNY641 total

includes taxes & fees

Sep 14 - Sep 15

Classic Room | Desk, laptop workspace, blackout drapes, iron/ironing board

Comfort Room | Private kitchen | Fridge, microwave, paper towels, dining table

Comfort Room | Bathroom | Rainfall showerhead, hair dryer, towels, soap

Red Bud Country Inn

Red Bud

CNY572

CNY635 total

includes taxes & fees

Sep 12 - Sep 13

Cabin, 1 Queen Bed | Private kitchen | Mini-fridge, stovetop, cookware/dishes/utensils, paper towels

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

CNY678

CNY1,075 total

includes taxes & fees

Oct 6 - Oct 7

Classic Room, 1 King Bed | Down comforters, desk, laptop workspace, blackout drapes

Family Room, 2 Double Beds | Down comforters, desk, laptop workspace, blackout drapes

Briarwood Inn of Sparta

Sparta

CNY664

CNY737 total

includes taxes & fees

Sep 16 - Sep 17

Premium bedding, desk, blackout drapes, iron/ironing board

Quality Inn Farmington

Farmington

CNY386

CNY443 total

includes taxes & fees

Sep 13 - Sep 14

View all properties

Go beyond your typical stay in St Mary

Pet friendly

Pool

Family friendly

Check out reviews of St Mary hotels guests love

Holiday Inn Express & Suites Perryville by IHG

8/10 Good

"clean room. breakfast, same as other chains"

Quality Inn Farmington

10/10 Excellent

"Very nice hotel and the beds are so comfortable"

Madison Inn Lodge

10/10 Excellent

"Nice and clean friendly staff"

Holiday Inn Express & Suites Farmington by IHG

10/10 Excellent

"Clean and well maintained as you would expect from this chain."

Frequently asked questions

How much does a hotel room cost in St Mary?

You can choose a great hotel in St Mary from CNY409 with properties to suit all budgets and needs. If you're after an affordable hotel in St Mary that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at St Mary hotels?

Discover great deals on St Mary hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on St Mary hotels.

Can I book St Mary hotels with free cancellation?

In order to book a refundable St Mary hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What hotels do travelers like in St Mary?

Guests like Baymont by Wyndham Chester IL, Microtel Inn & Suites by Wyndham Sainte Genevieve and Triangle Inn Motel.

Can I book a refundable accommodation in St Mary?

If you need the flexibility to change your travel plans to St Mary, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in St Mary be like during my vacation?

The warmest months in St Mary are usually July and August with an average temp of 75°F. January and February are the chilliest months when the average temp is 38°F. The rainiest months are April and May.

Why should I book my St Mary accommodation with Hotels.com?

There are plenty of reasons to book your St Mary travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

Book Hotels in St Mary on Hotels.com