Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in East Prairie on Hotels.com. These East Prairie hotels consistently deliver on comfort, location and traveler experience. Last updated on .
Hotels in East Prairie
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Where to stay in East Prairie?

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,000 reviews)
The price is CNY744
CNY855 total
includes taxes & fees
Jun 21 - Jun 22

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (469 reviews)
The price is CNY723
CNY819 total
includes taxes & fees
Jun 28 - Jun 29

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (416 reviews)
The price is CNY507
CNY562 total
includes taxes & fees
Jul 9 - Jul 10

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (578 reviews)
The price is CNY710
CNY804 total
includes taxes & fees
Jul 19 - Jul 20

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very Good, (772 reviews)
The price is CNY383
CNY414 total
includes taxes & fees
Jun 21 - Jun 22

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (92 reviews)
The price is CNY744
CNY842 total
includes taxes & fees
Jun 25 - Jun 26

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very Good, (64 reviews)
The price is CNY560
CNY639 total
includes taxes & fees
Jun 19 - Jun 20

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very Good, (1,013 reviews)
The price is CNY562
CNY641 total
includes taxes & fees
Jul 19 - Jul 20

Quality Inn Union City US 51
Quality Inn Union City US 51Union City
8.2 out of 10, Very Good, (525 reviews)
The price is CNY420
CNY498 total
includes taxes & fees
Jul 5 - Jul 6

Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityUnion City
8.6 out of 10, Excellent, (571 reviews)
The price is CNY426
CNY506 total
includes taxes & fees
Jun 19 - Jun 20

Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
9.2 out of 10, Wonderful, (399 reviews)
The price is CNY535
CNY636 total
includes taxes & fees
Jul 12 - Jul 13

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.6 out of 10, (641 reviews)
The price is CNY402
CNY446 total
includes taxes & fees
Jul 12 - Jul 13

Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHGUnion City
9.4 out of 10, Exceptional, (330 reviews)
The price is CNY744
CNY883 total
includes taxes & fees
Jul 12 - Jul 13

Hampton Inn Union City
Hampton Inn Union CityUnion City
9.6 out of 10, Exceptional, (186 reviews)
The price is CNY721
CNY856 total
includes taxes & fees
Jun 28 - Jun 29

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (789 reviews)
The price is CNY524
CNY597 total
includes taxes & fees
Jun 21 - Jun 22

Reelfoot Lake Inn
Reelfoot Lake InnTiptonville
7.2 out of 10, Good, (498 reviews)
The price is CNY471
CNY541 total
includes taxes & fees
Jun 21 - Jun 22

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,000 reviews)
The price is CNY460
CNY524 total
includes taxes & fees
Jun 21 - Jun 22

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (18 reviews)
The price is CNY827
CNY936 total
includes taxes & fees
Jul 5 - Jul 6

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (106 reviews)
The price is CNY483
CNY536 total
includes taxes & fees
Jul 1 - Jul 2

Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
6.8 out of 10, (139 reviews)
The price is CNY413
CNY491 total
includes taxes & fees
Jun 19 - Jun 20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in East Prairie
Pet friendly
Family friendly
Top landmarks in East Prairie
Learn more about East Prairie
East Prairie is well-known for its attractions such as Big Oak Tree State Park and Mississippi River.

Check out reviews of East Prairie hotels guests love

New Orleans Inn Portageville
8/10 Good
Frequently asked questions
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