Hotels in Penwell

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Where to stay in Penwell?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Penwell on Hotels.com. These Penwell hotels consistently deliver on quality, location and traveler experience. Last updated on September 13, 2026.

Outdoor pool, open 10:00 AM to 10:00 PM, cabanas (surcharge)

Breakfast, lunch, dinner and brunch served

1. Odessa Marriott Hotel & Conference Center

Odessa

CNY1,221

CNY1,404 total

includes taxes & fees

Sep 25 - Sep 26

Desk, soundproofing, iron/ironing board, cribs (free)

2. Holiday Inn Express & Suites Odessa I-20 by IHG

Odessa

CNY731

CNY849 total

includes taxes & fees

Sep 25 - Sep 26

Desk, laptop workspace, blackout drapes, iron/ironing board

3. MainStay Suites Odessa I-20

Odessa

CNY503

CNY579 total

includes taxes & fees

Sep 19 - Sep 20

Seasonal outdoor pool, open 7:00 AM to 10:00 PM, sun loungers

4. Hawthorn Extended Stay by Wyndham Odessa

Odessa

CNY664

CNY764 total

includes taxes & fees

Sep 18 - Sep 19

5. Sonesta Essential Hotels Odessa

Odessa

CNY530

CNY609 total

includes taxes & fees

Sep 18 - Sep 19

6. Spark by Hilton Odessa

Odessa

CNY490

CNY563 total

includes taxes & fees

Sep 25 - Sep 26

In-room safe, desk, iron/ironing board, cribs (free)

7. Hampton Inn by Hilton Odessa

Odessa

CNY600

CNY696 total

includes taxes & fees

Sep 19 - Sep 20

Coffee/tea maker, fridge, microwave, stovetop

8. Staybridge Suites Odessa - Interstate HWY 20 by IHG

Odessa

CNY651

CNY748 total

includes taxes & fees

Sep 18 - Sep 19

9. SureStay Plus Hotel by Best Western Odessa

Odessa

CNY563

CNY648 total

includes taxes & fees

Sep 16 - Sep 17

10. Comfort Inn & Suites, Odessa I-20

Odessa

CNY555

CNY639 total

includes taxes & fees

Sep 25 - Sep 26

11. Motel 6 Odessa, TX - 2nd Street

Odessa

CNY402

CNY463 total

includes taxes & fees

Sep 16 - Sep 17

12. Microtel Inn & Suites Odessa TX

Odessa

CNY429

CNY494 total

includes taxes & fees

Sep 20 - Sep 21

Desk, iron/ironing board, WiFi (free), bed sheets

13. La Quinta Inn by Wyndham Odessa

Odessa

CNY441

CNY507 total

includes taxes & fees

Sep 25 - Sep 26

14. Villa West Inn

Odessa

CNY416

CNY478 total

includes taxes & fees

Sep 14 - Sep 15

15. Fairfield Inn & Suites Odessa

Odessa

CNY622

CNY730 total

includes taxes & fees

Sep 25 - Sep 26

16. TownePlace Suites by Marriott Odessa

Odessa

CNY651

CNY748 total

includes taxes & fees

Sep 26 - Sep 27

Premium bedding, pillowtop beds, desk, WiFi (free)

17. Quality Inn Odessa near University

Odessa

CNY461

CNY530 total

includes taxes & fees

Sep 17 - Sep 18

Room, 2 Queen Beds | Hypo-allergenic bedding available, minibar, in-room safe, desk

18. Hilton Garden Inn Odessa

Odessa

CNY523

CNY601 total

includes taxes & fees

Sep 20 - Sep 21

19. Holiday Inn Express Hotel & Suites Odessa by IHG

Odessa

CNY624

CNY717 total

includes taxes & fees

Sep 20 - Sep 21

Desk, iron/ironing board, WiFi (free), alarm clocks

20. Comfort Suites Odessa near University

Odessa

CNY472

CNY543 total

includes taxes & fees

Oct 3 - Oct 4

View all properties

Go beyond your typical stay in Penwell

Pet friendly

Pool

Family friendly

Check out reviews of Penwell hotels guests love

Staybridge Suites Odessa - Interstate HWY 20 by IHG

10/10 Excellent

"Very pet friendly. Would definitely stay there again."

Comfort Inn & Suites, Odessa I-20

10/10 Excellent

"Our Room itself was excellent, clean and well stocked. We did ask for Handicap preference however, those accommodations were not met. The breakfast "menu" was not what we expected but adequate. Due to a number of Contractors on site, we did not get to enjoy the full breakfast experience as most of the food was gone by the time we made our way to the diner area. Overall, the stay was great, the Staff was very helpful and the Room was very nice. Thank you"

Deluxe Inn By Capital O Odessa I-20

8/10 Good

"Parking was very simple and room was very spacious"

Motel 6 Odessa, TX - 2nd Street

10/10 Excellent

"This motel was the fastest check in ever. Clean comfortable and quiet. Would totally recommend"

Baymont by Wyndham Odessa University Area

10/10 Excellent

"Great place to stay and safe"

Frequently asked questions

How much does a hotel room cost in Penwell?

You can choose a great hotel in Penwell from CNY387 with properties to suit all budgets and needs. To find an affordable hotel in Penwell that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at Penwell hotels?

Discover great deals on Penwell hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. And make sure to check out our last-minute deals on Penwell hotels.

Can I book Penwell hotels with free cancellation?

In order to book a refundable Penwell hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Penwell?

If you're looking for hotels in central Penwell, check out Target Hospitality-Odessa West Lodge. Travelers love Target Hospitality-Odessa West Lodge for its location, as well as the restaurant, free buffet breakfast and free parking this lodge offers.

Can I book a refundable accommodation in Penwell?

If you're looking for the flexibility to change your plans to Penwell, most accommodations offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Penwell be like during my vacation?

June and July are typically the warmest months in Penwell when the average temp is 82°F. January and December are the coldest months when the average temperature is 50°F. September and May are the months with the most rain.

Why should I book my Penwell hotel through Hotels.com?

There are lots of reasons to book your Penwell trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

Book Hotels in Penwell on Hotels.com