Hotels in Greencastle

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Top 5 hotels in Greencastle at a glance

Hampton Inn Kirksville — 2.5-star hotel in Kirksville. Guest rating: 9.2/10 — Wonderful.
Super 8 by Wyndham Kirksville-University Area — 2.5-star hotel in Kirksville. Guest rating: 9.0/10 — Wonderful.
Holiday Inn Express & Suites Kirksville - University Area by IHG — 2.5-star hotel in Kirksville. Guest rating: 9.2/10 — Wonderful.
Quality Inn Kirksville — 2.5-star hotel in Kirksville. Guest rating: 7.6/10 — Good.
Baymont by Wyndham Kirksville University Area — 2.5-star hotel in Kirksville. Guest rating: 7.6/10 — Good.

Where to stay in Greencastle?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Greencastle on Hotels.com. These Greencastle hotels consistently deliver on comfort, location and traveler experience. Last updated on August 17, 2026.

Hampton Inn Kirksville

Kirksville

CNY763

CNY865 total

includes taxes & fees

Sep 6 - Sep 7

Room, 2 Double Beds, Non Smoking | Pillowtop beds, desk, blackout drapes, cribs (free)

Super 8 by Wyndham Kirksville-University Area

Kirksville

CNY472

CNY530 total

includes taxes & fees

Aug 21 - Aug 22

In-room safe, desk, laptop workspace, blackout drapes

Indoor pool, open 7 AM to 11 PM, sun loungers

Holiday Inn Express & Suites Kirksville - University Area by IHG

Kirksville

CNY742

CNY841 total

includes taxes & fees

Sep 6 - Sep 7

Quality Inn Kirksville

Kirksville

CNY480

CNY599 total

includes taxes & fees

Aug 23 - Aug 24

Superior Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Baymont by Wyndham Kirksville University Area

Kirksville

CNY487

CNY547 total

includes taxes & fees

Aug 24 - Aug 25

Combined shower/tub, free toiletries, towels

Knights Inn Kirksville

Kirksville

CNY459

CNY515 total

includes taxes & fees

Aug 19 - Aug 20

Desk, soundproofing, iron/ironing board (on request), WiFi (free)

Shower, free toiletries, hair dryer, towels

Budget Host Village Inn

Kirksville

CNY421

CNY473 total

includes taxes & fees

Aug 19 - Aug 20

Combined shower/tub, rainfall showerhead, towels, soap

Thousand Hills

Kirksville

CNY953

CNY1,010 total

includes taxes & fees

Sep 1 - Sep 2

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Go beyond your typical stay in Greencastle

Pet friendly

Check out reviews of Greencastle hotels guests love

Hampton Inn Kirksville

10/10 Excellent

"The rooms were clean and updated. The staff was great! The mother could of been better."

Holiday Inn Express & Suites Kirksville - University Area by IHG

8/10 Good

"Didn’t like being texted 8:30 in morning asking when I was checking out."

Knights Inn Kirksville

10/10 Excellent

"Good one, will stay again"

Baymont by Wyndham Kirksville University Area

8/10 Good

"Room was clean and comfortable"

Thousand Hills

10/10 Excellent

"Great location, cabin overlooking lake. Good food at restaurant. We sat on covered patio on lake "

Frequently asked questions

How much does a hotel room cost in Greencastle?

You can discover great hotels in Greencastle from CNY473 with properties to suit all budgets and needs. If you're after an affordable hotel in Greencastle that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Greencastle hotels?

Discover great deals on Greencastle hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. And make sure to check out our last-minute deals on Greencastle hotels.

Can I book Greencastle hotels with free cancellation?

It's easy to book a refundable Greencastle hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book a refundable hotel in Greencastle?

If you're looking for the flexibility to change your plans to Greencastle, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Greencastle be like during my vacation?

July and August are typically the warmest months in Greencastle when the average temp is 73°F. January and February are the coldest months when the average temperature is 32°F. May and June are the months with the most rain.

Why should I book my Greencastle hotel through Hotels.com?

There are lots of reasons to book your Greencastle trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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