Hotels in Williamsville

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Where to stay in Williamsville?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Williamsville on Hotels.com. These Williamsville hotels consistently deliver on quality, location and traveler experience. Last updated on October 12, 2026.

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A calm lake with a wooden dock and a forested island in the distance.

A bedroom with a wooden bed, a bench, and a window.

1. Lake Wappapello

Williamsville

CNY602

CNY635 total

includes taxes & fees

Oct 13 - Oct 14

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A corner market with a refrigerated display case and a pantry area.

2. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

CNY649

CNY733 total

includes taxes & fees

Oct 18 - Oct 19

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

3. Hampton Inn Poplar Bluff

Poplar Bluff

CNY609

CNY682 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a reception desk, seating area, and large windows.

An indoor swimming pool with a clear view of the outside through large windows.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

4. Drury Inn & Suites Poplar Bluff

Poplar Bluff

CNY629

CNY711 total

includes taxes & fees

Oct 29 - Oct 30

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

A motel with a prominent '66' sign, large windows, and a flat roof.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

5. Motel 6 Poplar Bluff, MO

Poplar Bluff

CNY476

CNY533 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

6. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

CNY562

CNY635 total

includes taxes & fees

Oct 18 - Oct 19

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

7. Comfort Inn Poplar Bluff North

Poplar Bluff

CNY496

CNY560 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A laundry area with two stacked washers and dryers, a control panel, and a beige wall with a wooden panel above the dryers.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A two-story motel with a covered parking area and a bench outside.

8. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

CNY449

CNY508 total

includes taxes & fees

Oct 19 - Oct 20

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

A house with a red door, a porch with rocking chairs, and a wreath on the door.

A room with wooden paneling, a ceiling fan, a dining table with chairs, and a sofa.

A two-story house with a deck and a covered porch.

9. 40-acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

CNY803

CNY1,987 total

includes taxes & fees

Oct 21 - Oct 22

A rustic log cabin with a stone foundation, surrounded by trees and a wooden fence.

A park entrance with a sign for Sam A. Baker State Park and Mudlick Mountain Store and Grill.

A room with two bunk beds, a single bed, a ceiling fan, and a window with blinds.

A view through a window with a stone wall and a wooden structure in the background.

10. Sam A Baker State Park

Patterson

CNY904

CNY958 total

includes taxes & fees

Nov 3 - Nov 4

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Go beyond your typical stay in Williamsville

Pet friendly

Pool

Family friendly

Check out reviews of Williamsville hotels guests love

Hampton Inn Poplar Bluff

10/10 Excellent

"Hotel has been recently remodeled. Room was very clean. Staff was so helpful especially Sue who checked us in!"

Holiday Inn Poplar Bluff by IHG

8/10 Good

"Beds were ok. Could be updated, little hard but slept ok. AC was loins in our particular room. Told front desk n said they would be sure to have it looked at. The suite was incredible large."

Motel 6 Poplar Bluff, MO

8/10 Good

"I only stayed here from midnight until 5:30. It was clean, however the bed was very thin and uncomfortable and the heat/ac didn't work correctly which happens sometimes. The thermostat said 75 and it was freezing. It was a good place to crash for a few hours."

Lake Wappapello

10/10 Excellent

"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."

Sam A Baker State Park

8/10 Good

"Janie and her staff were great and very flexible. We had all the hep we needed for everything. Will comeback asap!"

Frequently asked questions

How much does a hotel room cost in Williamsville?

You can find top hotels in Williamsville from CNY508 with options to suit your budget and needs. If you're looking for an affordable hotel in Williamsville that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Williamsville hotels?

Discover great deals on Williamsville hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Williamsville hotels.

Can I book Williamsville hotels with free cancellation?

In order to book a refundable Williamsville hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book a refundable hotel in Williamsville?

If you want the flexibility to change your plans to Williamsville, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Williamsville be like during my vacation?

July and August are typically the warmest months in Williamsville when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and May are the months with the most rain.

Why should I book my Williamsville hotel with Hotels.com?

There are lots of reasons to book your Williamsville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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