Hotels in Six Mile

Q: What hotels do travelers recommend in Six Mile?

Guests like The Shepherd Hotel Downtown Clemson , Best Western Plus Clemson Hotel & Conference Center and Lakeside Lodge Clemson .

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Where to stay in Six Mile?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Six Mile on Hotels.com. These Six Mile hotels consistently deliver on comfort, location and traveler experience. Last updated on June 21, 2026.

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

CNY826 total

includes taxes & fees

Jul 3 - Jul 4

Tru by Hilton Seneca Clemson

Seneca

CNY768 total

includes taxes & fees

Jul 19 - Jul 20

Hampton Inn Anderson/ Alliance Business Park

Anderson

CNY853 total

includes taxes & fees

Jun 28 - Jun 29

Rodeway Inn & Suites Walhalla

Walhalla

CNY641 total

includes taxes & fees

Jul 15 - Jul 16

Residence Inn by Marriott Anderson Clemson

Anderson

CNY1,074 total

includes taxes & fees

Jun 28 - Jun 29

Country Inn & Suites by Radisson, Anderson, SC

Anderson

CNY760 total

includes taxes & fees

Jul 12 - Jul 13

Hilton Garden Inn Anderson

Anderson

CNY746 total

includes taxes & fees

Jun 28 - Jun 29

Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers

Fairfield Inn & Suites by Marriott Anderson Clemson

Anderson

CNY737 total

includes taxes & fees

Jun 28 - Jun 29

Best Western Plus Clemson Hotel & Conference Center

Clemson

CNY715 total

includes taxes & fees

Jun 24 - Jun 25

Days Inn by Wyndham Seneca / Clemson Area

Seneca

CNY519 total

includes taxes & fees

Jul 5 - Jul 6

Baymont by Wyndham Easley/Greenville

Easley

CNY480 total

includes taxes & fees

Jun 28 - Jun 29

Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Bathroom | Combined shower/tub, free toiletries, hair dryer, slippers

Comfort Inn & Suites Clemson - University Area

Clemson

CNY760 total

includes taxes & fees

Jul 11 - Jul 12

Hampton Inn Easley

Easley

CNY918 total

includes taxes & fees

Jul 19 - Jul 20

Desk, soundproofing, iron/ironing board, free WiFi

Budget Inn Express

Anderson

CNY496 total

includes taxes & fees

Jun 22 - Jun 23

Clemson University's James F. Martin Inn

Clemson

CNY1,044 total

includes taxes & fees

Jul 1 - Jul 2

Quality Inn Seneca Clemson Area US-123

Downtown

CNY636 total

includes taxes & fees

Jun 28 - Jun 29

Lakeside Lodge Clemson

Seneca

CNY916 total

includes taxes & fees

Jun 22 - Jun 23

Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

CNY893 total

includes taxes & fees

Jul 2 - Jul 3

In-room safe, blackout drapes, iron/ironing board, free WiFi

Holiday Inn Anderson by IHG

Anderson

CNY796 total

includes taxes & fees

Jul 19 - Jul 20

Days Inn by Wyndham Easley/Greenville/Clemson Area

Easley

CNY480 total

includes taxes & fees

Jun 28 - Jun 29

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Go beyond your typical stay in Six Mile

Pet friendly

Family friendly

Top landmarks in Six Mile

Mile Creek Park

Mile Creek Park is 5 mi (8 km) from central Six Mile, why not stop by during your stay. Want to stretch your legs some more? Head to DAR Monument, located nearby.

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Learn more about Six Mile

Six Mile is well-known for its attractions such as Lake Keowee and Mile Creek Park.

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Check out reviews of Six Mile hotels guests love

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"This cabin is SMALL and it is well appointed and feels bigger than it is because of the very high ceilings. The bed was comfortable, the room was very clean, the bathroom products smelled good, and the treats were a nice touch. My only real complaint is that we were supposed to receive a text the morning of our arrival with a cabin assignment and key code; we did not receive the text until 30 minutes before check in time. Had we been told that we wouldn't receive it until that time, we would not have worried. As it was, when we didn't receive it, we became concerned that we would not have a place to stay for the evening. It took a number of phone calls and chat sessions to get past AI and find some help."

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"Trip to visit Clemson University campus. Room was beautifully appointed, average size but comfortable. Lobby is gorgeous, southern organic. Restaurant on site great for breakfast and dinner. Employees were calm, friendly and made on feel at home. A nice bar with an indoor area and terrace too."

Inn @ Clemson

10/10 Excellent

"Clemson Inn’s Staff was top tier. I had recently had knee surgery and was one week out supporting my son’s dreams at a football camp at Clemson. The staff was so helpful to me, it was like having my own personal concierge. I needed my ice packs really frozen and the mini fridges in the room wasn’t going to cut it so they would put my ice packs in their freezer and get them every time I needed them. They helped me with my bags. They went above and beyond for me. I’m so grateful. If my son chooses Clemson, this will be my host hotel every time I visit. Thank you to Ashley (Manager), Kenzie, Alex, Victoria and Rahul. You all are simply amazing. I can’t thank you enough."

Frequently asked questions

How much does a hotel room cost in Six Mile?

You can choose a great hotel in Six Mile from CNY480 with properties to suit all budgets and needs. If you're after an affordable hotel in Six Mile that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Six Mile hotels?

Discover great deals on Six Mile hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Six Mile hotels.

Can I book Six Mile hotels with free cancellation?

To book a refundable Six Mile hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What hotels do travelers recommend in Six Mile?

Guests like The Shepherd Hotel Downtown Clemson, Best Western Plus Clemson Hotel & Conference Center and Lakeside Lodge Clemson.

Can I book refundable accommodations in Six Mile?

If you want the flexibility to change your travel plans to Six Mile, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Six Mile if I want a vacation home instead of a hotel?

If you're looking for a good alternative to a hotel, browse our selection of 47 vacation homes. You also might want to book one of 5 cottages or 12 cabins.

What will the weather in Six Mile be like during my visit?

The warmest months in Six Mile are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.

Why should I book my Six Mile hotel with Hotels.com?

There are plenty of reasons to book your Six Mile travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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