Hotels in Six Mile

Where to?

Dates

April 2026

May 2026

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Six Mile?

Inn @ Clemson

Clemson

Just minutes from Clemson University in a peaceful setting with lakefront convenience.

CNY684 total

includes taxes & fees

Mar 31 - Apr 1

Premium bedding, in-room safe, individually furnished, laptop workspace

Carolina Camp Cedar

Pickens

CNY1,335 total

includes taxes & fees

Mar 31 - Apr 1

Best Western Plus Clemson Hotel & Conference Center

Clemson

Ideal for Tigers fans, this lakeside hotel offers clean rooms and collegiate proximity.

CNY796 total

includes taxes & fees

Apr 3 - Apr 4

Lakeside Lodge Clemson

Seneca

Experience the heart of Clemson with quick access to Lake Keowee and university.

CNY935 total

includes taxes & fees

Mar 31 - Apr 1

Days Inn by Wyndham Clemson

Clemson

Take advantage of proximity to Clemson University with free continental breakfast daily.

CNY614 total

includes taxes & fees

Mar 31 - Apr 1

Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace

Comfort Inn & Suites Clemson - University Area

Clemson

Contemporary hotel with nearby university access and refreshing pool for travelers.

CNY743 total

includes taxes & fees

Apr 26 - Apr 27

Econo Lodge Clemson - University Area

Clemson

Close to Clemson University with free wifi and parking for a convenient campus stay.

CNY657 total

includes taxes & fees

Apr 5 - Apr 6

The Inn at Patrick Square

Clemson

Located near Clemson University with free parking and helpful staff to assist you.

CNY1,220 total

includes taxes & fees

Mar 31 - Apr 1

Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix

Clemson Memorabilia House

Clemson

Charming cottage minutes from Clemson University and Lake Hartwell for your campus visit.

CNY1,718 total

includes taxes & fees

Apr 2 - Apr 3

Tru by Hilton Seneca Clemson

Seneca

Stay minutes from Clemson University with free Wi-Fi and on-the-go breakfast.

CNY823 total

includes taxes & fees

Apr 26 - Apr 27

Hampton Inn Clemson-University Area

Clemson

Enjoy a convenient stay just 5 minutes from Clemson University campus.

CNY867 total

includes taxes & fees

Apr 26 - Apr 27

The Abernathy of Clemson

Clemson

Modern sanctuary near Clemson University with inviting bar and complimentary WiFi.

CNY1,236 total

includes taxes & fees

Apr 13 - Apr 14

Holiday Inn Express & Suites Clemson by IHG

Clemson

Stay close to Clemson University with a fitness center and daily free breakfast.

CNY944 total

includes taxes & fees

Apr 5 - Apr 6

Clemson University's James F. Martin Inn

Clemson

Enjoy sweeping golf course views at this Clemson University retreat with outdoor pool.

CNY1,143 total

includes taxes & fees

Mar 31 - Apr 1

Quality Inn Seneca Clemson Area US-123

Downtown

Stay close to Clemson University with pool access and traveler-approved helpful staff.

CNY634 total

includes taxes & fees

Apr 8 - Apr 9

Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

Best Western Seneca-Clemson

Seneca

Relax near Clemson University with a seasonal pool and complimentary amenities.

CNY711 total

includes taxes & fees

Apr 12 - Apr 13

Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

Relax in a scenic lakeside area with fitness options and complimentary perks.

CNY912 total

includes taxes & fees

Apr 12 - Apr 13

Pet-friendly Pickens Vacation Rental w/ Fire Pit

Pickens

Liberty Hall Bed and Breakfast

Pendleton

Charming B&B minutes from Clemson University with complimentary full breakfast.

CNY1,206 total

includes taxes & fees

Apr 13 - Apr 14

Days Inn by Wyndham Seneca / Clemson Area

Seneca

Enjoy a family getaway near Clemson University with a pool and complimentary breakfast.

CNY530 total

includes taxes & fees

Apr 8 - Apr 9

View all properties

Go beyond your typical stay in Six Mile

Family friendly

Pet friendly

Top landmarks in Six Mile

Mile Creek Park

Mile Creek Park is 5 mi (8 km) from central Six Mile, why not stop by during your stay. Want to stretch your legs some more? Head to DAR Monument, located nearby.

See properties

Keowee Springs Golf Course

You might want to play some rounds at Keowee Springs Golf Course, located 4.4 mi (7.1 km) from central Six Mile. If Keowee Springs Golf Course doesn't quite scratch your golfing itch, Keowee Key Golf Course is also nearby.

See properties

Learn more about Six Mile

Six Mile is well-known for its attractions such as Lake Keowee and Keowee Springs Golf Course.

See all hotels in Six Mile

Check out reviews of Six Mile hotels guests love

Lakeside Lodge Clemson

2/10 Terrible

"I must have gotten the absolute worst room here. The last time I stayed I had a great room with a balcony. This time, I got a "patio," that I even paid extra for that connected to the parking lot overlooking the highway on the fist floor. The room smelled AWFUL. Then I realized it must have been a pet room. Smelled like dog urine and the front desk said they couldn't move me because I had booked through Expedia. They offered to spray the room. With what, I have no idea. Probably some kind of dog urine spray reducer. Gross. Very disappointed. "

Frequently asked questions

How much does a hotel room cost in Six Mile?

You can choose a great hotel in Six Mile from CNY530 with properties to suit all budgets and needs. If you're after an affordable hotel in Six Mile that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Six Mile hotels?

Discover great deals on Six Mile hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Six Mile hotels.

Can I book Six Mile hotels with free cancellation?

To book a refundable Six Mile hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What hotels do travelers recommend in Six Mile?

Guests like Best Western Plus Clemson Hotel & Conference Center, The Shepherd Hotel Downtown Clemson and Lakeside Lodge Clemson.

Can I book refundable accommodations in Six Mile?

If you want the flexibility to change your travel plans to Six Mile, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Six Mile if I want a vacation home instead of a hotel?

If you're looking for a good alternative to a hotel, browse our selection of 48 vacation homes. You can also book one of the 12 cabins for your stay.

What will the weather in Six Mile be like during my visit?

The warmest months in Six Mile are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.

Why should I book my Six Mile hotel with Hotels.com?

There are plenty of reasons to book your Six Mile travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

Book Hotels in Six Mile on Hotels.com