Hotels in Six Mile

Where to?

Dates

March 2026

12

April 2026

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Six Mile?

Best Western Plus Clemson Hotel & Conference Center

Clemson

Ideal for Tigers fans, this lakeside hotel offers clean rooms and collegiate proximity.

CNY756 total

includes taxes & fees

Mar 15 - Mar 16

Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace

Comfort Inn & Suites Clemson - University Area

Clemson

Contemporary hotel with nearby university access and refreshing pool for travelers.

CNY804 total

includes taxes & fees

Apr 12 - Apr 13

Inn @ Clemson

Clemson

Just minutes from Clemson University in a peaceful setting with lakefront convenience.

Premium bedding, in-room safe, individually furnished, laptop workspace

Carolina Camp Cedar

Pickens

CNY1,326 total

includes taxes & fees

Mar 17 - Mar 18

Tru by Hilton Seneca Clemson

Seneca

Stay minutes from Clemson University with free Wi-Fi and on-the-go breakfast.

CNY836 total

includes taxes & fees

Mar 18 - Mar 19

Holiday Inn Express & Suites Clemson by IHG

Clemson

Stay close to Clemson University with a fitness center and daily free breakfast.

CNY938 total

includes taxes & fees

Mar 22 - Mar 23

The Inn at Patrick Square

Clemson

Located near Clemson University with free parking and helpful staff to assist you.

CNY1,212 total

includes taxes & fees

Mar 24 - Mar 25

Courtyard Marriott Clemson

Clemson

Just a quick drive to Clemson University, this hotel offers a refreshing outdoor pool.

CNY1,091 total

includes taxes & fees

Apr 5 - Apr 6

Lakeside Lodge Clemson

Seneca

Experience the heart of Clemson with quick access to Lake Keowee and university.

CNY929 total

includes taxes & fees

Mar 15 - Mar 16

The Abernathy of Clemson

Clemson

Modern sanctuary near Clemson University with inviting bar and complimentary WiFi.

Days Inn by Wyndham Clemson

Clemson

Take advantage of proximity to Clemson University with free continental breakfast daily.

CNY611 total

includes taxes & fees

Mar 15 - Mar 16

Hampton Inn Clemson-University Area

Clemson

Enjoy a convenient stay just 5 minutes from Clemson University campus.

CNY876 total

includes taxes & fees

Mar 23 - Mar 24

The Shepherd Hotel Downtown Clemson

Clemson

Stroll to Clemson University from this waterfront hotel with on-site dining.

CNY2,663 total

includes taxes & fees

Mar 14 - Mar 15

Clemson University's James F. Martin Inn

Clemson

Enjoy sweeping golf course views at this Clemson University retreat with outdoor pool.

CNY1,136 total

includes taxes & fees

Mar 15 - Mar 16

Quality Inn Seneca Clemson Area US-123

Downtown

Stay close to Clemson University with pool access and traveler-approved helpful staff.

CNY630 total

includes taxes & fees

Mar 29 - Mar 30

Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

Relax in a scenic lakeside area with fitness options and complimentary perks.

CNY944 total

includes taxes & fees

Mar 19 - Mar 20

Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

Best Western Seneca-Clemson

Seneca

Relax near Clemson University with a seasonal pool and complimentary amenities.

CNY764 total

includes taxes & fees

Apr 3 - Apr 4

Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix

Clemson Memorabilia House

Clemson

Charming cottage minutes from Clemson University and Lake Hartwell for your campus visit.

CNY1,708 total

includes taxes & fees

Mar 17 - Mar 18

Liberty Hall Bed and Breakfast

Pendleton

Charming B&B minutes from Clemson University with complimentary full breakfast.

Days Inn by Wyndham Seneca / Clemson Area

Seneca

Enjoy a family getaway near Clemson University with a pool and complimentary breakfast.

CNY520 total

includes taxes & fees

Mar 15 - Mar 16

View all properties

Go beyond your typical stay in Six Mile

Apartment

Family friendly

Top landmarks in Six Mile

Mile Creek Park

Mile Creek Park is 5 mi (8 km) from central Six Mile, why not stop by during your stay. Want to stretch your legs some more? Head to DAR Monument, located nearby.

See properties

Keowee Springs Golf Course

You might want to play some rounds at Keowee Springs Golf Course, located 4.4 mi (7.1 km) from central Six Mile. If Keowee Springs Golf Course doesn't quite scratch your golfing itch, Keowee Key Golf Course is also nearby.

See properties

Learn more about Six Mile

Six Mile is well-known for its attractions such as Lake Keowee and Keowee Springs Golf Course.

See all hotels in Six Mile

Lake Keowee is a man–made reservoir in the United States in the state of South Carolina. It was created to serve the needs of a power utility as well as public recreational purposes. One of my favorite places to go in the summer. The water really is that color.

Check out reviews of Six Mile hotels guests love

The Inn at Patrick Square

8/10 Good

"Parking was fine. Room was very small; shared space with the elevator shaft."

Days Inn by Wyndham Anderson

10/10 Excellent

"I was very pleased with my visit at the Days Inn in Anderson, South Carolina. Jennifer, who was the front desk agent that afternoon was very helpful and even let me check in early. The room was extremely clean and quiet and comfortable. I totally give it five stars for being affordable and friendly and comfortable, and even having a breakfast in the morning. This hotel is a great value with excellent service. "

Frequently asked questions

How much does a hotel room cost in Six Mile?

You can choose a great hotel in Six Mile from CNY520 with properties to suit all budgets and needs. If you're after an affordable hotel in Six Mile that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Six Mile hotels?

Discover great deals on Six Mile hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Six Mile hotels.

Can I book Six Mile hotels with free cancellation?

To book a refundable Six Mile hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What hotels do travelers recommend in Six Mile?

Guests like Best Western Plus Clemson Hotel & Conference Center, The Shepherd Hotel Downtown Clemson and Wooded Cottage - 3 Mi to Clemson University.

Can I book refundable accommodations in Six Mile?

If you want the flexibility to change your travel plans to Six Mile, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Six Mile if I want a vacation home instead of a hotel?

If you're looking for a good alternative to a hotel, browse our selection of 48 vacation homes. You can also book one of the 12 cabins for your stay.

What will the weather in Six Mile be like during my visit?

The warmest months in Six Mile are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.

Why should I book my Six Mile hotel with Hotels.com?

There are plenty of reasons to book your Six Mile travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

Book Hotels in Six Mile on Hotels.com