Hotels in Mayo

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Check prices for these dates

Tonight
Dec 17 - Dec 18
Tomorrow
Dec 18 - Dec 19
This weekend
Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

Where to stay in Mayo?

Free daily buffet breakfast
Hampton Inn Spartanburg-North I-85
Hampton Inn Spartanburg-North I-85
2.5 star property
8.8 out of 10, Excellent, (1004)
  • cleanliness
    Peaceful retreat north of Spartanburg with seasonal pool and fitness options.
The price is CNY549
CNY609 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hampton Inn Spartanburg-North I-85
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Mayo and vicinity

Seasonal outdoor pool
Quality Inn Gaffney I-85

Quality Inn Gaffney I-85

Quality Inn Gaffney I-85
2.5 star property
Gaffney
7.6 out of 10, Good, (354)
The price is CNY384
CNY430 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Quality Inn Gaffney I-85
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out reviews of Mayo hotels guests love

Comfort Inn & Suites Spartanburg North

Comfort Inn & Suites Spartanburg North

10/10 Excellent
"Very comfortable beds quiet clean room they weren’t skimpy with towels or other supplies and really put a lot into their Christmas tree - not the bare minimum like most places these days and location for traveling is perfect! We stayed here twice & plan to again! Also the price was very reasonable!"
Sue 1-night trip
Posted 4 days ago
Comfort Inn & Suites Spartanburg North

Frequently asked questions

How much does a hotel room cost in Mayo?
You can discover great hotels in Mayo from CNY569 with properties to suit all budgets and needs. If you're after an affordable hotel in Mayo that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Mayo hotels?
Discover great deals on Mayo hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Mayo hotels.
Can I book Mayo hotels with free cancellation?
In order to book a refundable Mayo hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What accommodations do travelers recommend in Mayo?
Guests like Spartanburg Marriott, Holiday Inn Express Gaffney by IHG and Hampton Inn Spartanburg-North I-85.
Can I book a refundable hotel in Mayo?
If you're looking for the flexibility to change your plans to Mayo, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Mayo be like during my visit?
July and August are typically the warmest months in Mayo when the average temp is 77°F. January and February are the coldest months when the average temperature is 46°F. December and April are the months with the most rain.
Why should I book my Mayo accommodation with Hotels.com?
There are lots of reasons to book your Mayo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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