Hotels in Odessa

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Check prices for these dates

Tonight
Oct 5 - Oct 6
Tomorrow
Oct 6 - Oct 7
Next weekend
Oct 10 - Oct 12
In two weeks
Oct 17 - Oct 19

Where to stay in Odessa?

Mark Twain Motor Inn
Exterior

Mark Twain Motor Inn

2.5 star property
5.8 out of 10, (227)
Mark Twain Motor Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out reviews of Odessa hotels guests love

Cayuga Blu Hotel

Cayuga Blu Hotel

10/10 Excellent
"Breakfast was better than I tbought we we ete getting, especially with fresh fruit. Only issue in area was had to drive to find a place for dinner but Crossroads was really good."
John 2-night trip
Posted 2 days ago
Cayuga Blu Hotel

Frequently asked questions

What accommodations do travelers like in Odessa?
Guests like The Hotel Laurel at Seneca.
Can I book refundable hotels in Odessa?
If you need the flexibility to change your travel plans to Odessa, most hotels provide refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Odessa be like during my vacation?
July and August are typically the warmest months in Odessa when the average temp is 67°F. January and February are the coldest months when the average temperature is 29°F. October and June are the months with the most rain.
Why should I book my Odessa hotel through Hotels.com?
There are lots of reasons to book your Odessa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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