Hotels in Cherokee
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Where to stay in Cherokee?
Heritage PLACE HOTEL IUKA
Heritage PLACE HOTEL IUKA
2.5 star property
Iuka
9.0 out of 10, Wonderful, (126)
9.0/10
Wonderful
(126)
- Friendly staff and convenient access to Iuka's attractions await at this motel.
10 Mi to Tennessee River: Blue Willow-themed Home
10 Mi to Tennessee River: Blue Willow-themed Home
3.0 star property
Iuka
The price is CNY514
CNY514
CNY1,761 total
includes taxes & fees
Dec 29 - Dec 30
The ColdWater Inn
The ColdWater Inn
3.5 star property
Tuscumbia
9.0 out of 10, Wonderful, (648)
9.0/10
Wonderful
(648)
- Discover comfortable accommodations near Alabama Music Hall of Fame in Tuscumbia.
The price is CNY615
CNY615
CNY683 total
includes taxes & fees
Dec 21 - Dec 22
Lake Park Inn
Lake Park Inn
2.0 star property
Iuka
9.6 out of 10, Exceptional, (12)
9.6/10
Exceptional
(12)
- Stay by the beautiful reservoir with a refreshing outdoor pool in Iuka, MS.
The price is CNY803
CNY803
CNY875 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Days Inn by Wyndham Muscle Shoals Florence
Days Inn by Wyndham Muscle Shoals Florence
2.0 star property
Muscle Shoals
8.6 out of 10, Excellent, (992)
8.6/10
Excellent
(992)
- Peaceful Alabama retreat with a fitness center and daily full breakfast included.
The price is CNY444
CNY444
CNY492 total
includes taxes & fees
Dec 24 - Dec 25
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
2.0 star property
Tuscumbia
8.2 out of 10, Very Good, (1000)
8.2/10
Very Good
(1000)
- Enjoy easy access to Muscle Shoals music heritage from this modern hotel.
The price is CNY443
CNY443
CNY492 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Inn & Suites Tuscumbia - Muscle Shoals
Comfort Inn & Suites Tuscumbia - Muscle Shoals
2.5 star property
Tuscumbia
8.2 out of 10, Very Good, (249)
8.2/10
Very Good
(249)
- Just 7 minutes from Alabama Music Hall of Fame, this Tuscumbia hotel offers a seasonal pool.
The price is CNY881
CNY881
CNY978 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Red Roof Inn Muscle Shoals
Red Roof Inn Muscle Shoals
2.5 star property
Muscle Shoals
6.6 out of 10, (297)
6.6/10
(297)
- Perfect for budget-friendly stays near Fame Recording Studios with free perks.
The price is CNY528
CNY528
CNY586 total
includes taxes & fees
Dec 20 - Dec 21
Budget Inn & Suites
Budget Inn & Suites
2.5 star property
East Florence
7.6 out of 10, Good, (144)
7.6/10
Good
(144)
- Enjoy comfortable rooms with easy access to Tom Braly Stadium and regional attractions.
The price is CNY464
CNY464
CNY515 total
includes taxes & fees
Dec 20 - Dec 21
GunRunner Boutique Hotel
GunRunner Boutique Hotel
3.5 star property
Florence
9.4 out of 10, Exceptional, (188)
9.4/10
Exceptional
(188)
- Experience the heart of Florence with a rooftop terrace and soothing spa treatments.
The price is CNY1,306
CNY1,306
CNY1,507 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn & Suites Florence-Downtown
Hampton Inn & Suites Florence-Downtown
2.5 star property
Florence
9.2 out of 10, Wonderful, (701)
9.2/10
Wonderful
(701)
- Stay just minutes from the Shoals Community Theater with helpful staff and amenities.
The price is CNY1,260
CNY1,260
CNY1,449 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Baymont by Wyndham Florence/Muscle Shoals
Baymont by Wyndham Florence/Muscle Shoals
2.5 star property
Florence
7.2 out of 10, Good, (892)
7.2/10
Good
(892)
The price is CNY475
CNY475
CNY547 total
includes taxes & fees
Dec 20 - Dec 21
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
2.5 star property
Tuscumbia
9.2 out of 10, Wonderful, (624)
9.2/10
Wonderful
(624)
- Relax in rural Alabama with a sparkling indoor pool and complimentary hot breakfast.
The price is CNY852
CNY852
CNY933 total
includes taxes & fees
Dec 24 - Dec 25
Key West Inn
Key West Inn
2.0 star property
Tuscumbia
7.0 out of 10, Good, (183)
7.0/10
Good
(183)
- Comfortable motel near Alabama Music Hall of Fame with free Wi-Fi and parking.
The price is CNY528
CNY528
CNY586 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
2.5 star property
Florence
9.0 out of 10, Wonderful, (588)
9.0/10
Wonderful
(588)
- Unwind in this modern haven near Regency Square Mall with complimentary breakfast.
The price is CNY782
CNY782
CNY899 total
includes taxes & fees
Dec 21 - Dec 22
Residence Inn Florence Marriott
Residence Inn Florence Marriott
3.0 star property
East Florence
9.2 out of 10, Wonderful, (330)
9.2/10
Wonderful
(330)
- Relax near Regency Square Mall with outdoor pool and modern workout facilities.
The price is CNY852
CNY852
CNY980 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Florence Shoals Area
Comfort Suites Florence Shoals Area
2.5 star property
Florence
8.8 out of 10, Excellent, (754)
8.8/10
Excellent
(754)
- Relaxing hotel near Florence attractions with an indoor pool and free perks.
The price is CNY707
CNY707
CNY813 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Stricklin Hotel
The Stricklin Hotel
3.5 star property
Florence
8.8 out of 10, Excellent, (800)
8.8/10
Excellent
(800)
- Modern downtown retreat in Florence with two onsite eateries for dining options.
Renaissance Shoals Resort and Spa
Renaissance Shoals Resort and Spa
3.5 star property
East Florence
9.2 out of 10, Wonderful, (750)
9.2/10
Wonderful
(750)
The price is CNY1,753
CNY1,753
CNY2,016 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Budget inn
Budget inn
2.5 star property
Russellville
7.0 out of 10, Good, (132)
7.0/10
Good
(132)
- Enjoy a peaceful retreat near Eastside Park with 24-hour service and free perks.
The price is CNY416
CNY416
CNY460 total
includes taxes & fees
Dec 20 - Dec 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Cherokee and vicinity
7.6 out of 10, Good, (144)
7.6/10
Good
(144)
The price is CNY464
CNY464
CNY515 total
includes taxes & fees
Dec 20 - Dec 21
7.0 out of 10, Good, (132)
7.0/10
Good
(132)
The price is CNY416
CNY416
CNY460 total
includes taxes & fees
Dec 20 - Dec 21
Days Inn by Wyndham Muscle Shoals Florence
Days Inn by Wyndham Muscle Shoals Florence2.0 star property
Muscle Shoals
8.6 out of 10, Excellent, (992)
8.6/10
Excellent
(992)
The price is CNY444
CNY444
CNY492 total
includes taxes & fees
Dec 24 - Dec 25
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals2.0 star property
Tuscumbia
8.2 out of 10, Very Good, (1000)
8.2/10
Very Good
(1000)
The price is CNY443
CNY443
CNY492 total
includes taxes & fees
Dec 21 - Dec 22
Baymont by Wyndham Florence/Muscle Shoals
Baymont by Wyndham Florence/Muscle Shoals2.5 star property
Florence
7.2 out of 10, Good, (892)
7.2/10
Good
(892)
The price is CNY475
CNY475
CNY547 total
includes taxes & fees
Dec 20 - Dec 21
7.6 out of 10, Good, (123)
7.6/10
Good
(123)
The price is CNY484
CNY484
CNY534 total
includes taxes & fees
Dec 28 - Dec 29
7.0 out of 10, Good, (183)
7.0/10
Good
(183)
The price is CNY528
CNY528
CNY586 total
includes taxes & fees
Jan 16 - Jan 17, 2026
9.0 out of 10, Wonderful, (648)
9.0/10
Wonderful
(648)
The price is CNY615
CNY615
CNY683 total
includes taxes & fees
Dec 21 - Dec 22
9.0 out of 10, Wonderful, (126)
9.0/10
Wonderful
(126)
8.8 out of 10, Excellent, (754)
8.8/10
Excellent
(754)
The price is CNY707
CNY707
CNY813 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG
Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG2.5 star property
Florence
9.0 out of 10, Wonderful, (588)
9.0/10
Wonderful
(588)
The price is CNY782
CNY782
CNY899 total
includes taxes & fees
Dec 21 - Dec 22
9.6 out of 10, Exceptional, (12)
9.6/10
Exceptional
(12)
The price is CNY803
CNY803
CNY875 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites2.5 star property
Tuscumbia
9.2 out of 10, Wonderful, (624)
9.2/10
Wonderful
(624)
The price is CNY852
CNY852
CNY933 total
includes taxes & fees
Dec 24 - Dec 25
9.2 out of 10, Wonderful, (330)
9.2/10
Wonderful
(330)
The price is CNY852
CNY852
CNY980 total
includes taxes & fees
Dec 28 - Dec 29
Best Western Plus Russellville Hotel & Suites
Best Western Plus Russellville Hotel & Suites2.5 star property
Russellville
9.0 out of 10, Wonderful, (491)
9.0/10
Wonderful
(491)
The price is CNY824
CNY824
CNY905 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hampton Inn Pickwick Dam-At Shiloh Falls
Hampton Inn Pickwick Dam-At Shiloh Falls2.5 star property
Counce
9.0 out of 10, Wonderful, (415)
9.0/10
Wonderful
(415)
The price is CNY860
CNY860
CNY987 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites Tuscumbia - Muscle Shoals
Comfort Inn & Suites Tuscumbia - Muscle Shoals2.5 star property
Tuscumbia
8.2 out of 10, Very Good, (249)
8.2/10
Very Good
(249)
The price is CNY881
CNY881
CNY978 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hampton Inn Florence Midtown near University of North Alabama
Hampton Inn Florence Midtown near University of North Alabama2.5 star property
Florence
9.0 out of 10, Wonderful, (544)
9.0/10
Wonderful
(544)
The price is CNY895
CNY895
CNY1,030 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Florence-Downtown
Hampton Inn & Suites Florence-Downtown2.5 star property
Florence
9.2 out of 10, Wonderful, (701)
9.2/10
Wonderful
(701)
The price is CNY1,260
CNY1,260
CNY1,449 total
includes taxes & fees
Jan 11 - Jan 12, 2026
8.8 out of 10, Excellent, (800)
8.8/10
Excellent
(800)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Cherokee
Pet friendly
Family friendly
Cottage
Check out reviews of Cherokee hotels guests love
Comfort Suites Florence Shoals Area
10/10 Excellent
"Yes yes Yes. Yes "
Comfort Inn & Suites Tuscumbia - Muscle Shoals
10/10 Excellent
"Yes"
The ColdWater Inn
10/10 Excellent
"Great atmosphere and a great room at reasonable price. A Gem of a Hotel!"
Hampton Inn Pickwick Dam-At Shiloh Falls
10/10 Excellent
"The staff was wonderful to everyone. Room was clean. Loved the continental breakfast. "
Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites
10/10 Excellent
"The lady at the front desk was amazing. I can’t remember her name, but she was amazing and the room was very clean."
Days Inn by Wyndham Muscle Shoals Florence
10/10 Excellent
"Room 140 was nice and clean. Shower head was wonderful. Bed was a little firmer than I would like but it was fairly comfortable. Breakfast was adequate for a quick bite....cereal, toast, muffins, biscuits, fried eggs, and sausage, waffles, juices and coffee. Breakfast room was very nice and clean and the host did an excellent job. Only complaint had to do with some loud guest staying above us. They were contract workers who were very inconsiderate to others. The staff that I met were really nice and courteous. Overall it was a nice stay for a good price. "
Hampton Inn & Suites Florence-Downtown
10/10 Excellent
"Kind desk crew. "
Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals
10/10 Excellent
"Comfortable and clean. "
Baymont by Wyndham Florence/Muscle Shoals
10/10 Excellent
"Clean and everyone was nice "
Frequently asked questions
How much does a hotel room cost in Cherokee?
You can find top hotels in Cherokee from CNY460 with options to suit your budget and needs. If you're after an affordable hotel in Cherokee that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Cherokee hotels?
Discover great deals on Cherokee hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Cherokee hotels.
Can I book Cherokee hotels with free cancellation?
To book a refundable Cherokee hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Can I book refundable hotels in Cherokee?
If you want the flexibility to change your plans to Cherokee, most accommodations provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Cherokee if I want a vacation home instead of a hotel?
You'll find 5 vacation homes on our site.
What will the weather in Cherokee be like during my trip?
The warmest months in Cherokee are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 45°F. The rainiest months are April and March.
Why should I book my Cherokee hotel through Hotels.com?
There are plenty of reasons to book your Cherokee travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.