A calm lake with a forested island in the distance.

Hotels in Kirksville

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Check prices for these dates

Tonight

Oct 12 - Oct 13

Tomorrow

Oct 13 - Oct 14

This weekend

Oct 16 - Oct 18

Next weekend

Oct 23 - Oct 25

Where to stay in Kirksville?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Kirksville on Hotels.com. These Kirksville hotels consistently deliver on quality, location and traveler experience. Last updated on October 13, 2026.

A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.

A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.

A reception desk with two computer monitors, a printer, and a keyboard.

An indoor swimming pool with clear lane markings, a lifeguard chair, and multiple exits.

1. Holiday Inn Express & Suites Kirksville - University Area by IHG

Kirksville

CNY736

CNY834 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.

2. Hampton Inn Kirksville

Kirksville

CNY772

CNY875 total

includes taxes & fees

Oct 25 - Oct 26

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A modern hotel lobby with a reception desk, seating area, and large windows.

3. Super 8 by Wyndham Kirksville-University Area

Kirksville

CNY522

CNY586 total

includes taxes & fees

Oct 13 - Oct 14

A hotel room with a large bathtub, a bed, a desk, and a television.

A dining area with wooden tables and chairs, a kitchen in the background, and a sign indicating a breakfast buffet.

A spacious living area with a fireplace, a ceiling fan, and a reception desk.

A deck with outdoor furniture including chairs and a table, surrounded by trees and a blue fence.

4. Baymont by Wyndham Kirksville University Area

Kirksville

CNY427

CNY479 total

includes taxes & fees

Nov 2 - Nov 3

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A flat-screen TV on a wooden TV stand with a remote control, a small speaker, and a box of tissues.

A blue sofa with a floral pattern, a small black side table, and a telephone on a wooden shelf.

A row of vending machines with snacks and beverages.

5. Quality Inn Kirksville

Kirksville

CNY446

CNY561 total

includes taxes & fees

Nov 2 - Nov 3

A hotel room with two beds, a desk with a chair, a television, a lamp, and a window with blinds.

A kitchen with wooden cabinets, a marble countertop, and a grey backsplash.

A motel with a covered parking area, a brick facade, and a clear blue sky.

A hotel room with two beds, a sofa, a chair, a desk, and a lamp.

6. Knights Inn Kirksville

Kirksville

CNY455

CNY511 total

includes taxes & fees

Oct 13 - Oct 14

A wooden deck with tables and chairs overlooking a lake at sunset.

A lakeside property with multiple cabins, a well-maintained lawn, and a large body of water.

A bathroom with a shower, sink, toilet, and towel rack.

A compact hotel room with a bed, a small dining table with chairs, a refrigerator, a microwave, and a sink.

7. Thousand Hills

Kirksville

CNY705

CNY747 total

includes taxes & fees

Oct 13 - Oct 14

A reception area with a wooden counter, a brick wall, a computer, and a calendar.

A bathroom with a wooden vanity, a mirror, a sink, a toilet, and a shower curtain.

A multi-story building with a parking lot. There are several cars parked, including a white sedan and a black SUV. A bicycle is parked on the sidewalk. The building has red doors and a balcony with railings.

A motel with a two-story building, a parking lot, and a small front porch area.

8. Budget Host Village Inn

Kirksville

CNY415

CNY466 total

includes taxes & fees

Oct 13 - Oct 14

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

A living room with a flat-screen TV, fireplace, and a couch with pillows.

A hotel lobby with a reception desk, a coffee station, and seating areas.

A hotel lobby with a reception desk, seating area, and a sign for the general store.

9. Depot Inn and Suites

La Plata

CNY612

CNY663 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

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Tonight

A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.

A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.

A reception desk with two computer monitors, a printer, and a keyboard.

An indoor swimming pool with clear lane markings, a lifeguard chair, and multiple exits.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Kirksville

We have 1 left at

CNY997

per night

CNY1,130 total

includes taxes & fees

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A modern hotel lobby with a reception desk, seating area, and large windows.

Super 8 by Wyndham Kirksville-University Area

Kirksville

We have 1 left at

CNY522

per night

CNY586 total

includes taxes & fees

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.

Hampton Inn Kirksville

Kirksville

CNY1,064

per night

CNY1,206 total

includes taxes & fees

A hotel room with a large bathtub, a bed, a desk, and a television.

A dining area with wooden tables and chairs, a kitchen in the background, and a sign indicating a breakfast buffet.

A spacious living area with a fireplace, a ceiling fan, and a reception desk.

A deck with outdoor furniture including chairs and a table, surrounded by trees and a blue fence.

Baymont by Wyndham Kirksville University Area

Kirksville

We have 2 left at

CNY569

per night

CNY639 total

includes taxes & fees

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A flat-screen TV on a wooden TV stand with a remote control, a small speaker, and a box of tissues.

A blue sofa with a floral pattern, a small black side table, and a telephone on a wooden shelf.

A row of vending machines with snacks and beverages.

Quality Inn Kirksville

Kirksville

We have 2 left at

CNY584

per night

CNY716 total

includes taxes & fees

A hotel room with two beds, a desk with a chair, a television, a lamp, and a window with blinds.

A kitchen with wooden cabinets, a marble countertop, and a grey backsplash.

A motel with a covered parking area, a brick facade, and a clear blue sky.

A hotel room with two beds, a sofa, a chair, a desk, and a lamp.

Knights Inn Kirksville

Kirksville

We have 7 left at

CNY455

per night

CNY511 total

includes taxes & fees

A reception area with a wooden counter, a brick wall, a computer, and a calendar.

A bathroom with a wooden vanity, a mirror, a sink, a toilet, and a shower curtain.

A multi-story building with a parking lot. There are several cars parked, including a white sedan and a black SUV. A bicycle is parked on the sidewalk. The building has red doors and a balcony with railings.

A motel with a two-story building, a parking lot, and a small front porch area.

Budget Host Village Inn

Kirksville

We have 1 left at

CNY415

per night

CNY466 total

includes taxes & fees

Check out pet-friendly hotels in Kirksville

A hotel room with a large bed, a desk, a chair, a small table, a lamp, and a window.

A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.

A reception desk with two computer monitors, a printer, and a keyboard.

An indoor swimming pool with clear lane markings, a lifeguard chair, and multiple exits.

Holiday Inn Express & Suites Kirksville - University Area by IHG

Kirksville

CNY736

CNY834 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.

Hampton Inn Kirksville

Kirksville

CNY772

CNY875 total

includes taxes & fees

Oct 25 - Oct 26

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A modern hotel lobby with a reception desk, seating area, and large windows.

Super 8 by Wyndham Kirksville-University Area

Kirksville

CNY522

CNY586 total

includes taxes & fees

Oct 13 - Oct 14

A hotel room with two beds, a desk with a chair, a television, a lamp, and a window with blinds.

A kitchen with wooden cabinets, a marble countertop, and a grey backsplash.

A motel with a covered parking area, a brick facade, and a clear blue sky.

A hotel room with two beds, a sofa, a chair, a desk, and a lamp.

Knights Inn Kirksville

Kirksville

CNY455

CNY511 total

includes taxes & fees

Oct 13 - Oct 14

A reception area with a wooden counter, a brick wall, a computer, and a calendar.

A bathroom with a wooden vanity, a mirror, a sink, a toilet, and a shower curtain.

A multi-story building with a parking lot. There are several cars parked, including a white sedan and a black SUV. A bicycle is parked on the sidewalk. The building has red doors and a balcony with railings.

A motel with a two-story building, a parking lot, and a small front porch area.

Budget Host Village Inn

Kirksville

CNY415

CNY466 total

includes taxes & fees

Oct 13 - Oct 14

View all properties

Go beyond your typical stay in Kirksville

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pet friendly image

hot tub image

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Our prices for hotels in Kirksville are cheapest in March

Top landmarks in Kirksville

Truman State University

9.2/10 (152 reviews)

If you'd like to get a taste of Kirksville student life, check out Truman State University, located 0.5 mi (0.8 km) from central Kirksville.

Thousand Hills State Park

9.2/10 (78 reviews)

Why not relax on the waterfront and snap some great vacation pics at Thousand Hills State Park when visiting Kirksville.

Adair County Historical Society

The center of Kirksville is home to cultural attractions like Adair County Historical Society, so you might want to stop by during your stay. If you want to experience more of the culture Kirksville has to offer, head to Truman State University, Thousand Hills State Park, and A.T. Still University.

Museum of Osteopathic Medicine

If visiting museums in Kirksville are on your list, you might want to check out the upcoming exhibitions at Museum of Osteopathic Medicine, located in the heart of town. If you want to experience more of the culture Kirksville has to offer, head to Truman State University, Thousand Hills State Park, and A.T. Still University.

Learn more about Kirksville

Notable for its university life, Kirksville features attractions such as Thousand Hills State Park and Adair County Historical Society. This family-friendly city has something for everyone including sights like Museum of Osteopathic Medicine.

See all hotels in Kirksville

A calm lake with a forested island in the distance.

Check out reviews of Kirksville hotels guests love

A modern hotel lobby with multiple seating areas, including a bar and dining tables.

A hotel reception area with a modern design, featuring a reception desk, a large window, and a 'Treats' display.

A modern kitchen with a bar area, bar stools, a coffee station, and a large clock on the wall.

An indoor swimming pool with clear water, surrounded by blue lounge chairs and a table with chairs.

Hampton Inn Kirksville

Kirksville

10/10 Exceptional

United States

Deanna

A wooden deck with tables and chairs overlooking a lake at sunset.

A lakeside property with multiple cabins, a well-maintained lawn, and a large body of water.

A bathroom with a shower, sink, toilet, and towel rack.

A compact hotel room with a bed, a small dining table with chairs, a refrigerator, a microwave, and a sink.

Thousand Hills

Kirksville

10/10 Exceptional

United States

Lisa

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A modern hotel lobby with a reception desk, seating area, and large windows.

Super 8 by Wyndham Kirksville-University Area

Kirksville

10/10 Exceptional

United States

Grant

A hotel room with a large bathtub, a bed, a desk, and a television.

A dining area with wooden tables and chairs, a kitchen in the background, and a sign indicating a breakfast buffet.

A spacious living area with a fireplace, a ceiling fan, and a reception desk.

A deck with outdoor furniture including chairs and a table, surrounded by trees and a blue fence.

Baymont by Wyndham Kirksville University Area

Kirksville

10/10 Exceptional

United States

Vic

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A flat-screen TV on a wooden TV stand with a remote control, a small speaker, and a box of tissues.

A blue sofa with a floral pattern, a small black side table, and a telephone on a wooden shelf.

A row of vending machines with snacks and beverages.

Quality Inn Kirksville

Kirksville

10/10 Exceptional

United States

Andrew

A hotel room with two beds, a desk with a chair, a television, a lamp, and a window with blinds.

A kitchen with wooden cabinets, a marble countertop, and a grey backsplash.

A motel with a covered parking area, a brick facade, and a clear blue sky.

A hotel room with two beds, a sofa, a chair, a desk, and a lamp.

Knights Inn Kirksville

Kirksville

10/10 Exceptional

United States

Mark

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

A living room with a flat-screen TV, fireplace, and a couch with pillows.

A hotel lobby with a reception desk, a coffee station, and seating areas.

A hotel lobby with a reception desk, seating area, and a sign for the general store.

Depot Inn and Suites

La Plata

10/10 Exceptional

United States

Christina

Frequently Asked Questions

How much does a hotel room cost in Kirksville?

You can discover great hotels in Kirksville from CNY414 with properties to suit all budgets and needs. If you're after an affordable hotel in Kirksville that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Kirksville hotels?

Discover great deals on Kirksville hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Kirksville hotels.

Can I book Kirksville hotels with free cancellation?

In order to book a refundable Kirksville hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some of the best Kirksville hotels with free parking?

If you're arriving by car, choosing a great Kirksville hotel with free parking is a plus. Our travelers' favorites include:

Hampton Inn Kirksville: A hotel with an average guest rating of 9.2 out of 10
Holiday Inn Express & Suites Kirksville - University Area by IHG: A hotel with an average guest rating of 9.2
Super 8 by Wyndham Kirksville-University Area: A hotel with an average guest rating of 9

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