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Business Hotels in Cherokee

October 2026
November 2026

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Sep 25 - Sep 27
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Oct 2 - Oct 4

Business Hotels in Cherokee

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Cherokee on Hotels.com. These Cherokee Business Hotels consistently deliver on quality, location and traveler experience. Last updated on September 23, 2026.
A cozy lounge area with a stone fireplace, leather sofas, and a flat-screen TV.
Stonebrook Lodge with a large deer statue in front.
A restaurant with wooden tables and chairs, stone pillars, and a view of the outdoors through large windows.
A stone building with a glass door, outdoor seating, and a covered patio area.

1. Stonebrook Lodge Cherokee

Stonebrook Lodge Cherokee
Cherokee
CNY673
CNY774 total
includes taxes & fees
Oct 15 - Oct 16
Stonebrook Lodge Cherokee
A circular bar area with multiple seating arrangements and a central DJ booth.
A poolside bar area with seating and a view of the pool.
A spacious lobby with a central seating area, a large chandelier, and a Starbucks sign in the background.
A large indoor swimming pool with a high ceiling and large windows.

2. Harrah's Cherokee Casino Resort - A Caesars Rewards Destination

Harrah's Cherokee Casino Resort - A Caesars Rewards Destination
Cherokee
CNY355
CNY664 total
includes taxes & fees
Oct 6 - Oct 7
Harrah's Cherokee Casino Resort - A Caesars Rewards Destination
A coffee station with two coffee machines and a variety of coffee pods and cups.
A hotel room with two beds, a desk, a chair, a television, a microwave, and a refrigerator.
A hotel lobby with a snack bar, a refrigerator stocked with beverages, and a seating area with tables and chairs.
A gym with treadmills, a stationary bike, and a rowing machine.

3. Holiday Inn Express Hotel & Suites Cherokee / Casino by IHG

Holiday Inn Express Hotel & Suites Cherokee / Casino by IHG
Cherokee
CNY710
CNY816 total
includes taxes & fees
Oct 6 - Oct 7
Holiday Inn Express Hotel & Suites Cherokee / Casino by IHG
A hotel with a covered entrance, stone pillars, and a sign reading "Super 8".
A hotel room with two beds, a sofa, and two lamps.
A swimming pool with a small building in the background, surrounded by trees.
A lobby with a stone wall, beige sofas, and a reception desk.

4. Super 8 by Wyndham Cherokee

Super 8 by Wyndham Cherokee
Downtown Cherokee
CNY472
CNY543 total
includes taxes & fees
Sep 29 - Sep 30
Super 8 by Wyndham Cherokee
A swimming pool with lounge chairs, a sign indicating 'Welcome to the hotel', and a building with a green roof in the background.
A reception area with a reception desk, a seating area with tables and chairs, and a view of the parking lot through the glass doors.
A building with a brick entrance and a parking lot.
A hotel room with a bed, a desk, a chair, a nightstand with a lamp, and a door.

5. Days Inn by Wyndham Cherokee Near Casino

Days Inn by Wyndham Cherokee Near Casino
Cherokee
CNY450
CNY517 total
includes taxes & fees
Oct 4 - Oct 5
Days Inn by Wyndham Cherokee Near Casino
A hotel lobby with a large scenic wall mural, a seating area with a sofa and chairs, and a wooden floor.
A modern hotel lobby with a long communal table, bar stools, a small bar area, and a television screen.
A modern kitchen with a central island, bar stools, and pendant lighting.
A hotel room with a large bed, two bedside tables with lamps, a nightstand with a drawer, a painting on the wall, and a window with curtains.

6. Clarion Pointe Cherokee

Clarion Pointe Cherokee
Cherokee
CNY636
CNY731 total
includes taxes & fees
Sep 24 - Sep 25
Clarion Pointe Cherokee
A hotel room with a bed, a desk, a chair, a bathroom with a sink and mirror, and a television mounted on the wall.
A brick building with a covered porch, a garage door, and a small garden area with potted plants.
A dining area with a mix of booths and tables, a patterned carpet, and a window with a view of greenery.
A reception area with a wooden reception desk, a check-in counter, and a wall with the Microtel logo.

7. Microtel Inn & Suites by Wyndham Cherokee

Microtel Inn & Suites by Wyndham Cherokee
Whittier
CNY476
CNY561 total
includes taxes & fees
Oct 4 - Oct 5
Microtel Inn & Suites by Wyndham Cherokee
A hotel lobby with a reception desk, a stone wall, patterned chairs, and a lamp.
A building entrance with glass doors, a visible interior hallway, and a trash bin outside.
A kitchen area with a coffee machine, a waffle maker, and a sign indicating no breakfast outside.
Two single beds with wooden headboards, white bedding, and green throw blankets. There are framed botanical prints on the walls.

8. Bay Mountain Inn

Bay Mountain Inn
Downtown Cherokee
CNY425
CNY489 total
includes taxes & fees
Sep 24 - Sep 25
Bay Mountain Inn
A modern dining area with multiple tables and chairs, a fireplace, and a stone accent wall.
A modern bar area with a stone wall, a flat-screen TV, and bar stools.
A hotel with a central entrance, multiple floors, and a parking lot.
A long, narrow hallway with large windows on one side, allowing natural light to enter.

9. Comfort Inn Sylva - Cullowhee

Comfort Inn Sylva - Cullowhee
Sylva
CNY701
CNY793 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn Sylva - Cullowhee
A deck with outdoor seating overlooking a river, surrounded by lush greenery and a building with balconies.
A river with a stone pathway and a building with a balcony overlooking the river.
An indoor swimming pool with clear water, metal railings, and a view of the outside through large windows.
A spacious dining area with high ceilings, large windows, and modern furniture.

10. Best Western Plus River Escape Inn & Suites

Best Western Plus River Escape Inn & Suites
Dillsboro
CNY704
CNY795 total
includes taxes & fees
Oct 1 - Oct 2
Best Western Plus River Escape Inn & Suites
A hotel lobby with a staircase, a reception desk, and an exit sign.
A pool area with lounge chairs and a lifeguard station.
A hotel room with a bed, a desk with a flat-screen TV, a heater, and framed pictures on the wall.
A coffee station with a daydream blend coffee machine, a milk dispenser, and various food items.

11. Sleep Inn Bryson City - Cherokee Area

Sleep Inn Bryson City - Cherokee Area
Bryson City
CNY596
CNY673 total
includes taxes & fees
Sep 27 - Sep 28
Sleep Inn Bryson City - Cherokee Area
A hotel entrance with a covered driveway, stone facade, and landscaped garden.
A hotel room with two beds, a desk, a chair, a lamp, a telephone, and a painting on the wall.
A hotel with a pool, surrounded by well-maintained landscaping and a mountainous backdrop.
A modern kitchen with wooden cabinets, a central island, and a dining area with a glass table and chairs.

12. Best Western Smoky Mountain Inn

Best Western Smoky Mountain Inn
Waynesville
CNY693
CNY769 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Smoky Mountain Inn
A modern bedroom with a large bed, dark wall paneling, two bedside tables, and a window with a view.
A modern living room with a leather sofa, a wooden coffee table, and two bedside tables with lamps.
A compact living space with a TV, a dining table, a chair, a small refrigerator, and a wardrobe with a hanging rack.
A two-story motel with outdoor seating on the balconies, surrounded by greenery and hills.

13. Hotel Sylva

Hotel Sylva
Sylva
CNY968
CNY1,126 total
includes taxes & fees
Oct 7 - Oct 8
Hotel Sylva
An indoor swimming pool with clear water, white chairs, and a covered area with large windows.
A reception area with a stone wall, a door, and a sign for Quality Inn & Suites.
A row of modern multi-story buildings with a uniform architectural style, featuring a mix of stone and stucco exteriors, red roofs, and a central flagpole with an American flag.
A hotel room with a large bed, a window with plaid curtains, a bedside table, and a wall with green and white panels.

14. Quality Inn & Suites Maggie Valley - Cherokee Area

Quality Inn & Suites Maggie Valley - Cherokee Area
Maggie Valley
CNY439
CNY487 total
includes taxes & fees
Sep 30 - Oct 1
Quality Inn & Suites Maggie Valley - Cherokee Area
A hotel lobby with a fireplace, two armchairs, a sofa, and a coffee table.
A casino bar with multiple screens, slot machines, and a curved counter.
A hotel breakfast area with a refrigerator, fruit bowls, and a coffee station.
A building with a large glass facade, a brick exterior, and a sign indicating it is the Smoky Mountain Center for the Performing Arts.

15. Quality Inn Franklin

Quality Inn Franklin
Franklin
CNY736
CNY830 total
includes taxes & fees
Sep 23 - Sep 24
Quality Inn Franklin
A balcony with white chairs, a view of a green landscape with trees and a building, and a clear blue sky.
A dining area with a large window, a flat-screen TV, and a red carpet.
A kitchen with a refrigerator, cabinets, and a countertop with various items.
A two-story building with a balcony, a satellite dish, and a stone wall.

16. Econo Lodge Waynesville

Econo Lodge Waynesville
Waynesville
CNY542
CNY602 total
includes taxes & fees
Sep 23 - Sep 24
Econo Lodge Waynesville
A micro hotel with a covered entrance, multiple floors, and a sign indicating it is by Wyndham.
A reception area with a reception desk, a large window with curtains, and a sign for 'MICROTEL INN & SUITES BY WYNDHAM'.
A hotel room with a dining area, a sofa, and a TV.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

17. Microtel Inn & Suites By Wyndham Sylva Dillsboro Area

Microtel Inn & Suites By Wyndham Sylva Dillsboro Area
Sylva
CNY530
CNY599 total
includes taxes & fees
Sep 23 - Sep 24
Microtel Inn & Suites By Wyndham Sylva Dillsboro Area
A natural stream surrounded by dense greenery and a building with balconies.
A wooden chair on a balcony with a view of a forested area and a stream.
An indoor swimming pool with wooden walls and a tiled floor.
A hotel room with two beds, a desk with a TV, a lamp, and a view of greenery outside.

18. Ramada by Wyndham Maggie Valley

Ramada by Wyndham Maggie Valley
Maggie Valley
CNY464
CNY515 total
includes taxes & fees
Sep 23 - Sep 24
Ramada by Wyndham Maggie Valley
An indoor swimming pool with a glass ceiling, tiled floor, and seating area.
A modern hotel lobby with a blue sofa, two ottomans, a coffee table, and a framed picture on the wall.
A glass-enclosed pool area with lounge chairs, a diving board, and a view of the outside.
A modern hotel room with a large window, a blue sofa set, a small table, and a cart with a laptop.

19. Comfort Inn near Great Smoky Mountain National Park

Comfort Inn near Great Smoky Mountain National Park
Maggie Valley
CNY512
CNY568 total
includes taxes & fees
Sep 29 - Sep 30
Comfort Inn near Great Smoky Mountain National Park
A modern lounge area with a fireplace, purple sofas, a flat-screen TV, and a view of the outdoors.
A Clarion Hotel by Choice Hotels with a covered entrance, stone pillars, and a clear blue sky.
A modern reception area with a dark counter, a seating area, and a pizzeria sign in the background.
A hotel room with a large bed, a desk, a chair, a sofa, and a small ottoman.

20. Clarion Hotel Conference Center Maggie Valley

Clarion Hotel Conference Center Maggie Valley
Maggie Valley
CNY572
CNY635 total
includes taxes & fees
Sep 30 - Oct 1
Clarion Hotel Conference Center Maggie Valley
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Top neighborhoods in Cherokee

Downtown Cherokee

The Downtown Cherokee neighborhood has lots to see including Smokey Mountain Gold & Ruby Mine and Museum of the Cherokee Indian.

Top landmarks in Cherokee

A concrete tower with a circular observation platform, surrounded by dense forest and tall trees.

Clingmans Dome

9.0/10 (145 reviews)
You might want to head out to Clingmans Dome for some fresh mountain air and a bird's-eye view of Cherokee. Why not take a stroll along the riverfront and watch the sunset while you're here?
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A sign reading "Unto These Hills Outdoor Drama" against a stone wall.

Unto These Hills Outdoor Drama

8.8/10 (144 reviews)
Unto These Hills Outdoor Drama is 0.6 mi (1 km) from central Cherokee, why not stop by during your stay. Why not take a stroll along the riverfront and watch the sunset while you're here? If you enjoy the show and want to see another, Cherokee Mountainside Theatre is just a short walk away.
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A rustic log cabin in a forest.

Oconaluftee Indian Village

8.8/10 (325 reviews)
If you'd like to get a taste of Cherokee student life, check out Oconaluftee Indian Village, located 0.7 mi (1.2 km) from central Cherokee. Why not take a stroll along the riverfront and watch the sunset while you're here? If you want to experience more of the culture Cherokee has to offer, head to Harrahs Cherokee Casino, Unto These Hills Outdoor Drama, and Santa's Land Family Theme Park and Zoo.
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A roadside attraction named 'Santasland' with a gift shop, a fun park, and a zoo.

Santa's Land Family Theme Park and Zoo

7.6/10 (196 reviews)
Why not give yourself a treat with a trip to Santa's Land Family Theme Park and Zoo, one of the family attractions located 3.2 mi (5.2 km) from central Cherokee. Why not take a stroll along the riverfront and watch the sunset while you're here? If you have fun at Santa's Land Family Theme Park and Zoo, you'll love Cherokee Botanical Garden and Nature Trail, located nearby.
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A waterfall cascading over rocks in a forested area.
Photo by Pon Xayavong Photography

Soco Falls

8.8/10 (340 reviews)
Soco Falls is 8.6 mi (13.8 km) from central Cherokee, why not stop by during your stay.
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A sign for the Museum of the Cherokee Indian with a stone wall and greenery in the foreground.

Museum of the Cherokee Indian

8.8/10 (669 reviews)
If museums are on your list of things to see, you might want to browse the collections at Museum of the Cherokee Indian in Downtown Cherokee. Why not take a stroll along the riverfront and watch the sunset while you're here? If you want to see more of the museums in Cherokee, you can easily walk to Oconaluftee Indian Village.
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A rustic building with a sign for Ruby Mine and a sign for Gold Mine.

Smokey Mountain Gold & Ruby Mine

8.2/10 (238 reviews)
If you're planning a bit of sightseeing head to Smokey Mountain Gold & Ruby Mine— just one of the monuments in Downtown Cherokee. Why not take a stroll along the riverfront and watch the sunset while you're here? Cherokee has other landmarks you might want to visit such as Great Smoky Mountains Railroad.
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Oconaluftee Visitor Center

9.0/10 (222 reviews)
Immerse yourself in nature and spend the day at Oconaluftee Visitor Center, located 2.6 mi (4.2 km) from central Cherokee. Want to stretch your legs some more? Head to Oconaluftee Islands Park and Cherokee Botanical Garden and Nature Trail, both nearby.
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About the destination

Visitors really like Cherokee, especially its entertainment and riverfront. Activities like hiking give you a chance to enjoy the outdoors while you're in town. Have a relaxing day visiting Great Smoky Mountains National Park. While you're here, make time to enjoy other sights such as Harrahs Cherokee Casino.

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