A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

Business Hotels in Mytilene

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Business Hotels in Mytilene

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Mytilene on Hotels.com. These Mytilene Business Hotels consistently deliver on quality, location and traveler experience. Last updated on September 27, 2026.

A breakfast table with various dishes, a view of the sea, and buildings in the background.

A modern living room with a sofa, two coffee tables, and a TV.

A view from a room with a balcony overlooking a harbor, featuring a large cruise ship and a smaller boat.

1. Hotel Lesvion

Lesvos

CNY587

CNY682 total

includes taxes & fees

Oct 11 - Oct 12

A buffet with various food items including fruits, vegetables, and desserts.

A hotel room with a large bed, a desk, a chair, a small refrigerator, a staircase, and a nightstand with a lamp.

A multi-story hotel with a central courtyard, balconies, and a rooftop terrace.

A multi-story hotel with balconies, a central staircase, and a well-lit entrance.

2. Theofilos Paradise Boutique Hotel

Lesvos

CNY839

CNY995 total

includes taxes & fees

Oct 4 - Oct 5

A swimming pool with tiled flooring, lounge chairs, and a bar area.

An outdoor bar area with a pool view, wooden deck, and bar stools.

A modern hotel room with a large bed, bedside table, desk, and chair.

A spacious indoor area with multiple seating arrangements, large windows offering a view of the sea, and a modern architectural design.

3. Heliotrope Hotels

Lesvos

CNY584

CNY717 total

includes taxes & fees

Oct 1 - Oct 2

A pathway flanked by lush greenery and palm trees, leading to a distant structure.

A swimming pool with a stone building and outdoor seating area.

A room with a view of the sea through a window with white curtains. There is a small table with a decorative item on it.

A stone building with a central staircase, surrounded by palm trees and a cobblestone driveway.

4. Loriet Hotel

Lesvos

CNY700

CNY843 total

includes taxes & fees

Oct 1 - Oct 2

A nighttime view of a hotel with a swimming pool, outdoor seating area, and a view of the sea.

A nighttime view of a hotel with a swimming pool, outdoor seating, and a view of the sea.

An aerial view of a hotel with a central pool, multiple buildings, and a road in the foreground.

An outdoor dining area with white chairs and red sashes, overlooking the sea.

5. Lasia Hotel

Lesvos

CNY464

CNY588 total

includes taxes & fees

Sep 28 - Sep 29

A resort with a pool, outdoor seating, and a view of the sea at dusk.

A modern hotel room with a large bed, a dining area with a view of the sea, and a balcony with a table and chairs.

A dining area with a table and chairs, a vase with a flower, and a view of the sea through large windows.

A modern hotel room with a large bed, a desk, and a view of the ocean.

6. Mythical Coast Wellness Retreat

Lesvos

CNY625

CNY800 total

includes taxes & fees

Oct 1 - Oct 2

A room with a green sofa, a wooden bench, a chair, a small table, and a window with curtains.

A balcony with a view of a cityscape, featuring terracotta rooftops and a clear blue sky.

A balcony with two terracotta planters with flowers, a white chair, and a black metal railing.

A compact kitchen with a window, a sink, and a built-in oven.

7. Heliotrope The Studios

Lesvos

CNY649

CNY726 total

includes taxes & fees

Oct 3 - Oct 4

A modern kitchen with stainless steel appliances, a wooden countertop, and a dining area with a table and chairs.

A modern hotel room with a large bed, a wooden headboard, a wall-mounted shelf with plants, and a window with curtains.

A modern living room with a sofa, a small table, a TV, and a bookshelf with decorative items.

A modern living room with a grey sofa, wooden coffee table, and a dining area with a table and chairs.

8. Agora Apartments

Lesvos

CNY615

CNY689 total

includes taxes & fees

Oct 1 - Oct 2

A person standing on a balcony overlooking a pool and a modern building with a clear view of the sea.

A modern bar area with seating and a bar counter.

A person standing by a glass railing, holding a cup, with a view of the sea and mountains in the background.

A modern hotel with a swimming pool, outdoor seating, and a view of the sea.

9. Elysion Hotel

Lesvos

CNY747

CNY1,124 total

includes taxes & fees

Oct 3 - Oct 4

A restaurant with wooden ceiling beams, round pendant lights, white wicker chairs, and large windows offering a view of greenery.

A modern outdoor dining area with white wicker furniture and a wooden ceiling.

A modern bedroom with a wooden bunk bed, a wardrobe, and a desk.

A modern hotel room with a large bed, a bedside table, and a view of the outside.

10. Ampoulos Rooms & Apartments

Lesvos

CNY880

CNY979 total

includes taxes & fees

Sep 28 - Sep 29

A balcony with a view of the sea, a seating area, and a bed with pillows.

A modern kitchen with grey cabinets, a stainless steel sink, and a potted plant on the countertop.

A balcony with a view of the sea, a white pitcher with plants, and a building with a red roof.

A modern living room with a grey sofa, a small table with fruits and drinks, a flat-screen TV mounted on the wall, and a door leading to another room.

11. Olive Green Studios and Apartments

Lesvos

CNY1,032

CNY1,146 total

includes taxes & fees

Oct 14 - Oct 15

A garden with tropical flowers, a hammock, and thatched umbrellas.

A two-story building with a red-tiled roof, surrounded by palm trees and a well-maintained garden with red flowers.

A garden with thatched umbrellas, outdoor seating, and lush greenery.

A garden with red flowers, a pool, and thatched umbrellas.

12. Shine Studios

Lesvos

CNY377

CNY428 total

includes taxes & fees

Oct 5 - Oct 6

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Top landmarks in Mytilene

Mytilini Castle

9.0/10 (25 reviews)

You might want to get your camera out and head to Mytilini Castle— just one of the landmarks located 1 mi (1.7 km) from central Mytilene.

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Thermi Beach

7.8/10 (18 reviews)

Whether you want to collect beach glass or watch the sunset, Thermi Beach is a spot you might want to check out when visiting central Pirgi Thermis. Catch the sunset by the shore at Plaz Kanóni, just a short walk away.

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Thermes Gera Hot Springs

Thermes Gera Hot Springs is 4.1 mi (6.5 km) from central Mytilene, why not stop by during your stay.

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St Hermogenes Charamida Lesvos

St Hermogenes Charamida Lesvos is just one of the landmarks located 5.6 mi (9.1 km) from central Mytilene, so you might want to stop by for a few pics during your trip.

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Roman Aqueduct at Moria

8.0/10 (3 reviews)

If you're planning a bit of sightseeing during your trip, head to Roman Aqueduct at Moria— just one of the landmarks located 3 mi (4.9 km) from central Mytilene.

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Archaeological Site of Thermi

If you're planning a bit of sightseeing during your trip, head to Archaeological Site of Thermi— just one of the monuments in central Pirgi Thermis.

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Olive-press Museum of Archipelagos Society

The center of Mytilene is home to cultural attractions like Olive-press Museum of Archipelagos Society, so you might want to stop by during your stay. If you want to experience more of the culture Mytilene has to offer, head to Mytilini Castle, Port of Mytilene, and University of the Aegean.

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Museum of the Memorial of the Refugees of 1922

Museum of the Memorial of the Refugees of 1922 is 4 mi (6.5 km) from central Mytilene, why not stop by during your stay. If you want to experience more of the culture Mytilene has to offer, head to University of the Aegean, Port of Mytilene, and St Hermogenes Charamida Lesvos.

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About the destination

If you're looking to discover somewhere new, look no further than Mytilene. Whether you're planning to stay for a night or for the week, the area around Mytilene has accommodations to fit every need. Search for hotels in Mytilene with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Mytilene hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Mytilene hotel deals are here with our lowest price guarantee.

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Cheap Hotels in Mytilene
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