Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Mytilene on Hotels.com. These Mytilene hotels consistently deliver on quality, location and traveler experience. Last updated on September 26, 2026.
Surrounded by picturesque views, this Lesvos retreat sits minutes from cultural attractions like the Ecclesiastical Byzantine Museum. Grab a drink at the bar or enjoy meals at the restaurant with room service available. Nearby shops, restaurants, and local nightlife complete your Greek island adventure.
Immerse yourself in paradise at this Lesvos gem with a seasonal outdoor pool and rejuvenating spa services. Just 10 minutes from Port of Mytilene, the hotel offers a rooftop terrace, poolside bar, hot tub, and sauna for ultimate relaxation.
Unwind at this coastal haven with a seasonal outdoor pool and children's splash area. Just 4 minutes from Mytilene Airport, near Teriade Museum, the hotel offers 4 bars, 2 restaurants, and poolside refreshments with free breakfast, WiFi, and parking.
Discover a peaceful Lesvos retreat near Theophilos Museum. Each studio comes equipped with washing machines and refrigerators for added convenience. Enjoy free WiFi and room service while exploring nearby cultural attractions.
Unwind in a tranquil villa featuring a private kitchen and cozy fireplace. The outdoor pool offers a refreshing escape, while the spa provides rejuvenating facials. Explore nearby Kochylia and the Olive Oil Museum with easy access from this serene garden sanctuary.
This beach aparthotel offers an outdoor pool with poolside bar, free breakfast, and apartments with premium bedding. Just 4 minutes from Mytilene International Airport, you're near Teriade and Theophilos Museums while enjoying free WiFi and parking.
Escape to Lesvos at this welcoming guesthouse where lush garden views await. Just a short drive from Port of Mytilene, explore nearby Temple of Messon and the Ecclesiastical Byzantine Museum between relaxing on the terrace. Enjoy free WiFi and parking.
Lasia Hotel on Lesvos offers a refreshing outdoor pool and garden terrace, perfect for unwinding with a drink from the bar. Enjoy free breakfast, WiFi, and parking while exploring nearby Kochylia and the Museum of Industrial Olive Oil Production.
Discover comfortable accommodations at this air-conditioned guesthouse within 15 minutes' walk of the Port of Mytilene. Enjoy free WiFi while exploring nearby Theophilos Museum. Convenient access to Mytilene International Airport just 15 minutes away by car.
Embrace seaside serenity at this Lesvos luxury retreat offering 5 restaurants and multiple pools. The spa provides indulgent massages while beach amenities await outside. Near Museum of Industrial Olive Oil Production with free breakfast, WiFi and parking.
Discover seaside elegance at this luxurious Lesvos retreat near Kochylia. Enjoy 3 tennis courts, multiple pools, and 2 restaurants with refreshing drinks at the bars. Free breakfast, WiFi and parking complete your perfect beach getaway.
Bask in Mediterranean charm at this Lesvos guesthouse featuring a refreshing outdoor pool with dedicated bar. Free breakfast, convenient room service, and lush garden spaces create a tranquil retreat just moments from cultural highlights like Teriade Museum.
Unwind at this tranquil Lesvos guesthouse offering free WiFi and parking. Garden surroundings create a peaceful atmosphere while Thermi Beach and the Archaeological Site are just moments away for cultural exploration and seaside relaxation.
Experience seaside tranquility at this Lesvos guesthouse overlooking the bay. Splash in the outdoor pool, sip drinks at the poolside bar, or unwind on the terrace. With free WiFi and parking, plus easy access to Chalatsés and Xéres Evreiakís attractions.
Escape to this serene Lesvos hotel offering rejuvenating massages and a welcoming beach bar. Comfortable studios feature refrigerators and microwaves, while the garden and terrace provide peaceful relaxation spots near Old Soap Factory.
This relaxing Lesvos beachfront hotel offers both poolside cocktails and deli snacks at 2 bars. Enjoy the terrace, free WiFi, and parking while exploring nearby Skala Kallonis Beach and Kalloni Salt Pans.
Escape to this inviting Lesvos guesthouse where terrace views complement garden tranquility. Unwind in practical rooms with refrigerators and microwaves, while enjoying free WiFi and parking. Kalloni Salt Pans and local beaches await just minutes away, with room service adding extra comfort.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Whether you want to collect beach glass or watch the sunset, Thermi Beach is a spot you might want to check out when visiting central Pirgi Thermis. Catch the sunset by the shore at Plaz Kanóni, just a short walk away.
St Hermogenes Charamida Lesvos is just one of the landmarks located 5.6 mi (9.1 km) from central Mytilene, so you might want to stop by for a few pics during your trip.
If you're planning a bit of sightseeing during your trip, head to Roman Aqueduct at Moria— just one of the landmarks located 3 mi (4.9 km) from central Mytilene.
The center of Mytilene is home to cultural attractions like Olive-press Museum of Archipelagos Society, so you might want to stop by during your stay. If you want to experience more of the culture Mytilene has to offer, head to Mytilini Castle, Port of Mytilene, and University of the Aegean.
Museum of the Memorial of the Refugees of 1922 is 4 mi (6.5 km) from central Mytilene, why not stop by during your stay. If you want to experience more of the culture Mytilene has to offer, head to University of the Aegean, Port of Mytilene, and St Hermogenes Charamida Lesvos.
The sea view pool and the landscaping were so impressive and tranquil. Wish we could have stayed longer.
The Molivos apartment was very nice and relaxing with 2 bedrooms , 2 bathrooms, 2 verandas, kitchen. LR, communal pool, 2 extra sunbeds on the grass under a tree, and parking.
Perfect apartment for a family or friends. We are going again in July with our 21 and 23 year old children to have quality time.
Marina and the staff were very friendly. There’s a little bar near the pool for drinks...
First of all, all the hotel staff were extremely friendly, kind, and helpful. We thank them all individually. The hotel's location, cleanliness, and the variety and quality of the breakfasts were excellent. We are eagerly looking forward to staying at this hotel again. Thank you very much.
I stayed only one night, before an early flight to Athens. The manager and staff were extremely helpful-- not only phoning the car rental agency for me but fetching a package for me, from a courier in downtown Mytilene, and delivering it to my door. (If they hadn't done that, I would never have got the package.) The room-service menu is small, but I was surprised to get any food at all in such a little hotel, and the salad I ordered was good.
Boutique hotel nestled on the waterfront with ample onsite amenities such as a pool and cafe/bar. Located near other great places like a bakery, cafes, restaurants and beaches. Easy to get to other parts of the island of Mytilini while traveling by auto. Highly recommend.
Beautiful balcony view from bedrooms! Shower tends 2 overflow and not all rooms are equipped with a kettle! Aside from that, the hostess was very helpful!
a fine hotel, recently refurbished, about an 7 euro ride from the aiport and a 16 euro ride to the center of town. bus right across the street runs about every hour (2 or 3-hour intervals on saturday and sunday), and does not run much after 8:30 at night. breakfast was intruiging: the only place i've ever seen an authentic greek coffee maker (with the hot sand) which requires the long instrument, and local sheep butter. as long as the distance from the port does not bother you, this is your...
This hotel is owner operated. Owner directly helped me to check in. Room was clean and spacious. Phenomenal value for the money. It is the 3rd time we have stayed at Paradisos.
Our vacation at the Loriet Hotel in Mithilini was amazing. Everything was perfect. We really had very good time in there. Thanks for the hospitality and the hygiene conditions. Having new plans for coming back again.
The property and staff is fantastic! They have created a warm and welcoming environment at this beautiful hotel. You get a very Mytilinean experience with so many amenities and conveniences. We would stay here again!
You can discover great hotels in Mytilene from CNY225 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Mytilene that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Mytilene hotels?
Discover great deals on Mytilene hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Mytilene hotels.
Can I book Mytilene hotels with free cancellation?
To book a refundable Mytilene hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are the top-rated luxury hotels in Mytilene?
Some of the most popular luxury hotels in Mytilene are Theofilos Paradise Boutique Hotel, Mythical Coast Wellness Retreat, and Elysion Hotel. Theofilos Paradise Boutique Hotel is a luxury hotel with a high guest rating amongst our travelers, and it offers 4 hot springs, a full-service spa and a seasonal outdoor pool. Mythical Coast Wellness Retreat and Elysion Hotel are also popular luxury stays in great Mytilene locations.
What are some of the best Mytilene beach hotels?
For a beachy vacation in Mytilene, Thermi Beach and Charamida Beach are some of the best places to visit. Stay at a well-reviewed Mytilene beach hotel and enjoy your vacation. Check out Mythical Coast Wellness Retreat if you're after a hotel that's near the water. With a beachfront setting plus an outdoor pool and a full-service spa, our travelers rate it highly at 8.6 out of 10.
What are some top pet-friendly hotels in Mytilene?
Consider one of our travelers' favorite pet-friendly hotels in Mytilene:
You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Mytilene.
What are some of the best hotels in Mytilene for couples?
Choose a top-rated Mytilene romantic hotel and enjoy your couple's getaway. Our travelers love Elysion Hotel, a hotel with 2 restaurants and an outdoor pool. Another romantic hotel with top reviews is Mythical Coast Wellness Retreat. This hotel offers a beach and 5 restaurants for a perfect stay. Discover more hotels in Mytilene on Hotels.com for couples by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are the top Mytilene hotels with a pool?
For a little extra luxury, discover some of the best Mytilene hotels with a pool. Theofilos Paradise Boutique Hotel is a great hotel with a seasonal outdoor pool and a children's pool, and a guest rating of 9.6 out of 10. Plus, you can make the most of its 4 hot springs and full-service spa. Elysion Hotel is a popular hotel that features an outdoor pool and a children's pool along with 2 restaurants and 3 outdoor tennis courts. To find more stays in Mytilene with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".
What are some of the best Mytilene hotels with free parking?
If you're driving, a great Mytilene hotel with free parking is a bonus. Our travelers' favorites include:
Elysion Hotel: A hotel with an average guest rating of 9.2
Lasia Hotel: A hotel with an average guest rating of 9
What are the top Mytilene boutique hotels?
Book your stay at a stylish boutique hotel in Mytilene. Theofilos Paradise Boutique Hotel is a popular hotel with our travelers, offering guests a seasonal outdoor pool and a children's pool as well as individually furnished guestrooms with down comforters and minibars.
What are some popular hotels in central Mytilene?
For hotels in central Mytilene, check out Theofilos Paradise Boutique Hotel and Hotel Lesvion. Travelers love Theofilos Paradise Boutique Hotel for its location, as well as the seasonal outdoor pool, children's pool and 4 hot springs this hotel offers. Hotel Lesvion is another popular central hotel with a restaurant, a bar/lounge and a free buffet breakfast.
