Hotels in San Luis

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Dates

November 2025

11

December 2025

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Where to stay in San Luis?

Check out reviews of San Luis hotels guests love

Hotel y Restaurante Villa Quetzaly

10/10 Excellent

"Super nice place, lovely, super helpful staff! The showers weren’t hot, but not freezing. Great base for exploring the area. We hiked to the top of one of the mountains with a guide arranged by the manager. THEN floated through a cave on tubes. Super fun day! "

Frequently asked questions

Can I book refundable accommodations in San Luis?

If you want the flexibility to change your plans to San Luis, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in San Luis be like during my trip?

San Luis is a great place to visit to enjoy the sunshine any time of year with an average temp of 71°F.

Why should I book my San Luis hotel with Hotels.com?

There are lots of reasons to book your San Luis trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.