Hotels in Santa Isabel

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Apr 3 - Apr 4
Tomorrow
Apr 4 - Apr 5
This weekend
Apr 3 - Apr 5
Next weekend
Apr 10 - Apr 12

Where to stay in Santa Isabel?

Exterior
Cocoloco - Catamaran Lagoon 52F SAN BLAS
Cocoloco - Catamaran Lagoon 52F SAN BLAS
3.0 star property
Narganá
  • cleanliness
    Sail the stunning San Blas archipelago on a floating paradise with sea views.
The price is CNY14,064
CNY15,470 total
includes taxes & fees
May 1 - May 2
Cocoloco - Catamaran Lagoon 52F SAN BLAS
View from property
Cabañas Isla Nubesidub San Blas
Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
The price is CNY2,644
CNY2,909 total
includes taxes & fees
May 4 - May 5
Cabañas Isla Nubesidub San Blas
Exterior
Cabañas Nalunega San Blas
Cabañas Nalunega San Blas
2.0 star property
Narganá
The price is CNY2,446
CNY2,690 total
includes taxes & fees
May 4 - May 5
Cabañas Nalunega San Blas
Property grounds
Cabins on paradise San Blas island
Cabins on paradise San Blas island
2.0 star property
Narganá
  • cleanliness
    Explore Panama's San Blas island from a rustic cabin steps away from paradise.
The price is CNY1,853
CNY2,038 total
includes taxes & fees
Apr 5 - Apr 6
Cabins on paradise San Blas island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Learn more about Santa Isabel

While in the area, you can enjoy nearby attractions like Porvenir Museum.

See all hotels in Santa Isabel
Scenic Coiba Island Aerial View

Check out reviews of Santa Isabel hotels guests love

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
Ryan 4-night trip
Posted 3 weeks ago
Private Ocean-Front Cabin with private bathroom on San Blas Island

Frequently asked questions

How much does a hotel room cost in Santa Isabel?
You can discover great hotels in Santa Isabel from CNY2,038 with properties to suit all budgets and needs. To find an affordable hotel in Santa Isabel that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".
How can I find deals and earn rewards at Santa Isabel hotels?
Discover great deals on Santa Isabel hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. And make sure to check out our last-minute deals on Santa Isabel hotels.
Can I book Santa Isabel hotels with free cancellation?
In order to book a refundable Santa Isabel hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Can I book a refundable accommodation in Santa Isabel?
If you need the flexibility to change your plans to Santa Isabel, most hotels provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Isabel be like during my vacation?
With an average temperature of 78°F during the coldest months, Santa Isabel is a great place to visit any time of year.
Why should I book my Santa Isabel accommodation with Hotels.com?
There are lots of reasons to book your Santa Isabel trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.