Hotels in Mesotopos

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Where to stay in Mesotopos?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Mesotopos on Hotels.com. These Mesotopos hotels consistently deliver on quality, location and traveler experience. Last updated on October 10, 2026.

A seaside terrace with a long white table, potted plants, and outdoor seating.

A waterfront restaurant with outdoor seating, a covered deck, and a view of the water.

A hotel entrance with a wooden door, a staircase, and potted plants.

An outdoor café with tables and chairs, overlooking a body of water.

1. Sappho Hotel

Lesvos

CNY425

CNY480 total

includes taxes & fees

Oct 31 - Nov 1

A bedroom with a bed, bedside table, and a view of the outside.

A modern kitchen with a built-in stove, a sink, and a countertop with a coffee machine. There is a window with a view of the outside.

A modern building with large windows and a white facade.

A narrow courtyard with a stone staircase, potted plants, and a red door.

2. Eressian Lodgings Apartments

Lesvos

CNY302

CNY593 total

includes taxes & fees

Oct 11 - Oct 12

A swimming pool with a wooden deck, lounge chairs, and a building with multiple windows.

A wooden staircase with a glass vase and a plant on the right side.

A spacious bedroom with a large bed, two windows with curtains, a wooden desk, and a decorative ceiling medallion.

A gated entrance to a hotel with a sign reading "ERESSIAN HOTEL HAMAMHAMAM SPA".

3. Eressian Hotel & Hammam Spa

Lesvos

CNY4,588

CNY5,026 total

includes taxes & fees

Oct 13 - Oct 14

A room with a sliding glass door leading to an outdoor area, a round table with two chairs, a sofa, a small table with a bottle, a mirror, and a wooden desk.

A wooden table with an open book, a cup, and a vase with dried plants.

A hotel room with a bed, a desk with a computer, a chair, and a view of the outdoors.

A modern room with a sofa, a dining table with a book and a cup, a small table with a bowl, and a view through a large window.

4. Apolithon Premium Houses

Lesvos

CNY607

CNY680 total

includes taxes & fees

Oct 11 - Oct 12

A nighttime swimming pool with a central rock feature, surrounded by lounge chairs and umbrellas, and a building with arched windows in the background.

A hotel room with a large bed, two bedside lamps, a nightstand, a mirror, and a wall-mounted air conditioner.

A residential street at night with houses on either side, a well-lit palm tree, and a clear sky.

A hotel with a swimming pool, hot tubs, and outdoor seating areas.

5. Imerti Hotel

Lesvos

CNY686

CNY789 total

includes taxes & fees

Oct 30 - Oct 31

A garden with tropical flowers, a hammock, and thatched umbrellas.

A modern hotel room with a large bed, a bedside table with a lamp, a dresser, and a window with curtains.

A two-story building with a red-tiled roof, surrounded by palm trees and a well-maintained garden with red flowers.

A garden with red flowers, a pool, and thatched umbrellas.

6. Shine Studios

Lesvos

CNY370

CNY420 total

includes taxes & fees

Oct 11 - Oct 12

A buffet with various food items and a brick wall in the background.

A swimming pool with blue lounge chairs and a stone pathway leading to it.

A buffet with various food items and a floral arrangement.

A grassy area with palm trees, a swing set, and a building with a tiled roof.

7. Kaloni village apartments

Lesvos

CNY370

CNY436 total

includes taxes & fees

Oct 17 - Oct 18

A terrace with a table set for dining, chairs, and a view of the sea and town.

A coastal town with a hilltop castle, beach with umbrellas, and seaside houses.

A poolside area with lounge chairs and umbrellas, a dining table set for two, and a view of a hill with buildings.

A modern bedroom with a bed, a sofa, a bedside table, a TV, and a large window.

8. Hotel Delfinia

Lesvos

CNY750

CNY859 total

includes taxes & fees

Oct 11 - Oct 12

A neatly arranged bedroom with a large bed, bedside tables, a dresser, a mirror, and a hanging light fixture.

A stone building with multiple windows, some with shutters, and a visible door.

A white outdoor fountain with a statue, surrounded by greenery and a stone wall.

A covered outdoor area with a dining set, chairs, and a table.

9. Archontiko Petras 1821

Lesvos

CNY595

CNY652 total

includes taxes & fees

Nov 3 - Nov 4

A blue building with balconies, a ladder, and potted plants.

A view through an open window of a narrow street with buildings, one with a blue door and another with a red door.

A narrow stone pathway leading to a building with a blue facade, a white door, and a small garden area with various plants and a decorative stone planter.

A room with two beds, a desk, a chair, a television, and a window with a view of greenery.

10. Nicholas House

Lesvos

CNY472

CNY532 total

includes taxes & fees

Oct 31 - Nov 1

A poolside setting with a drink, an orange, and a lemon on the edge of the pool.

A spacious lobby with multiple seating areas, a reception desk, and a large mirror reflecting the space.

An outdoor bar area with a counter, bar stools, and a seating area with tables.

A coastal hotel with multiple buildings, a beach, and a view of the sea.

11. Aegeon Hotel

Lesvos

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Go beyond your typical stay in Mesotopos

Family friendly

Check out reviews of Mesotopos hotels guests love

Eleia Seafront Rooms & Villas

10/10 Excellent

"Amazing trip. We were there in off-season in October, and still beautiful with great hospitality."

Hotel Delfinia

10/10 Excellent

"Beautiful spot, clean rooms, amazing shower! Friendly staff and great food"

Sappho Hotel

8/10 Good

"I was “in-between” places and Sappho Hotel was in the budget, location and availability for three nights. My ONLY negative comment and it’s not just Sappho hotel, is that there are no designated smoking areas. As a non smoker you’re subjected to it everywhere. Please note: I was a smoker, I love to smoke, so I am not judging. Rather you are just surrounded by it constantly. From the rooms next door, from below and above. Otherwise i enjoyed my time in Greece and at Sappho Hotel"

Aeolian Village Beach Resort

8/10 Good

"We had a lovely time at this hotel with the kids. The kids pool is perfect to let adults rest on the side but keep a close eye on them. Rooms are basic but clean. The lift needs an upgrade as it is like entering a prison and the wardrobes of Narnia at the same time! Great coffee's from the pool car."

Birds Bay

10/10 Excellent

"Beautiful property great accommodations, had a luxury sweet with sea view. Property is terraced with reception, pool and food available on the lower section of the property. Beautiful infinity pool with absolutely stunning views especially the sunsets. Close to Petra and is about a 25 min walk but if you’re not in great shape get a cab. Also very close to Molivos which has great dining, shopping and cultural/historical attractions. Great part of the island to explore. Staff was friendly room was spacious with a fridge, hot plate, toaster, coffee maker, TV and a washing machine which was great. Also a nice patio to dine or spend time relaxing and an additional balcony off the bedroom to watch the sunsets from. Hope to come back next year."

molivos hills

10/10 Excellent

"Beautiful and quiet location in the olive groves. Very clean rooms and property. Pool was great and clean. The kitchen in unit was well stocked with everything needed. The outside property had outside seating area with flowers and pretty landscaping. Furnishings in apartment were up to date and nice. Air conditioning kept the place very cool. Molyvos was just a few minutes drive. Very nice stay and will stay again in the future."

Aegeon Hotel

10/10 Excellent

"⭐⭐⭐⭐⭐ My stay at Aegeon Hotel was one of the most memorable experiences of my life. The owner and every member of the staff were truly exceptional. Their kindness, warmth, and genuine hospitality touched my heart. In today’s world, it is incredibly rare to meet people with such beautiful hearts. I sincerely hope that one day they will have the opportunity to visit Canada or Türkiye, because I would be honored to welcome them into my home and show them the same kindness they showed me. The hotel was spotless, peaceful, and beautifully maintained. Every morning we enjoyed a wonderful breakfast made with fresh local products. The olives from Lesvos were simply incredible—without a doubt some of the most delicious I have ever tasted. The owner went above and beyond to help me whenever I needed anything, making me feel more like a family friend than a guest. If I had more time, I would have happily stayed much longer. As I was leaving, they surprised me with a beautiful gift. It was such a thoughtful gesture that I will treasure forever. I will never forget their generosity, their smiles, and the way they made me feel at home. Thank you from the bottom of my heart for making our stay so special. We didn’t just leave with wonderful memories of Lesvos—we left with memories of truly wonderful people. I look forward to returning one day. With my deepest gratitude, Tamer Yuksel Canada"

Kaloni village apartments

10/10 Excellent

"Too Y and clean"

Frequently asked questions

How much does a hotel room cost in Mesotopos?

You can choose a great hotel in Mesotopos from CNY420 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Mesotopos that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Mesotopos hotels?

Discover great deals on Mesotopos hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Mesotopos hotels.

Can I book Mesotopos hotels with free cancellation?

It's easy to book a refundable Mesotopos hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Mesotopos?

If you're looking for hotels in central Mesotopos, check out Eressian Hotel & Hammam Spa. Travelers love Eressian Hotel & Hammam Spa for its location, as well as the outdoor pool, full-service spa and steam room this hotel offers.

What hotels do travelers like in Mesotopos?

Guests like Aeolian Village Beach Resort, Sappho Hotel and Eressian Hotel & Hammam Spa.

Can I book refundable hotels in Mesotopos?

If you need the flexibility to change your plans to Mesotopos, most properties offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Mesotopos be like during my visit?

The warmest months in Mesotopos are usually August and July with an average temp of 77°F. January and February are the chilliest months when the average temp is 51°F. The rainiest months are January and December.

Why should I book my Mesotopos hotel with Hotels.com?

There are plenty of reasons to book your Mesotopos travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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