Hotels in O Brien

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Nov 16 - Nov 17
Tomorrow
Nov 17 - Nov 18
Next weekend
Nov 21 - Nov 23
In two weeks
Nov 28 - Nov 30

Where to stay in O Brien?

Lobby
Hampton Inn & Suites Lake City
Hampton Inn & Suites Lake City
2.5 star property
9.4 out of 10, Exceptional, (1000)
The price is CNY693
CNY779 total
includes taxes & fees
Nov 30 - Dec 1
Hampton Inn & Suites Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See more propertiesforward arrow

Learn more about O Brien

O Brien is well-known for its attractions such as Suwannee River and Ichetucknee River.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Check out reviews of O Brien hotels guests love

Tru by Hilton Lake City

Tru by Hilton Lake City

10/10 Excellent
"Spotlesd"
Roxy 1-night trip
Posted 2 days ago
Tru by Hilton Lake City

Frequently asked questions

Can I book refundable hotels in O Brien?
If you want the flexibility to change your travel plans to O Brien, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in O Brien if I want a vacation home instead of a traditional hotel?
You'll find 6 vacation homes on our site.
What will the weather in O Brien be like during my vacation?
July and August are typically the warmest months in O Brien when the average temp is 80°F. January and February are the coldest months when the average temperature is 58°F. June and August are the months with the most rain.
Why should I book my O Brien hotel with Hotels.com?
There are lots of reasons to book your O Brien trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring