Hotels in Osco

City, hotel name, or address

Dates

Travelers

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Osco?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Osco on Hotels.com. These Osco hotels consistently deliver on quality, location and traveler experience. Last updated on October 15, 2026.

A hotel room with a sofa, two armchairs, a small table, a lamp, and a window with curtains.

A hotel lobby with a pool view, a clock on the wall, and a patterned carpet.

1. Best Western Geneseo Inn

Geneseo

CNY702

CNY780 total

includes taxes & fees

Nov 10 - Nov 11

A Comfort Inn & Suites building with a clear entrance, a covered parking area, and a well-maintained landscape.

A reception area with a wooden reception desk, a glass door entrance, and a small reception desk with a computer.

A hotel dining area with multiple tables and chairs, a buffet station, and a refrigerator.

A hotel room with two beds, a chair, a nightstand with a lamp, and a window with curtains.

2. Comfort Inn & Suites East Moline near I-80

East Moline

CNY582

CNY671 total

includes taxes & fees

Nov 8 - Nov 9

A reception area with a desk, computer, and chairs. There is a door leading outside and a bulletin board on the wall.

A reception area with a black reception desk, a blue wall with a circular artwork, and a framed certificate on the wall.

A hotel room with a bed, two bedside tables, a desk with a computer, a television, and a microwave.

A hotel hallway with a patterned carpet, doors on either side, and a sign indicating a staff-only area.

3. Regency Inn Geneseo

Geneseo

CNY435

CNY482 total

includes taxes & fees

Oct 21 - Oct 22

A spacious lobby with a fireplace, comfortable seating, and a television screen.

A spacious lobby with a reception desk, seating area with armchairs, a coffee table, and a television mounted on the wall.

A spacious lobby with a stone fireplace, comfortable seating, and a large flat-screen TV.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a view of the outside through large windows.

4. Residence Inn Marriott Moline

Moline

CNY623

CNY704 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, a window with a view of a snowy landscape, a balcony with chairs, and a wall-mounted air conditioner.

A hotel room with a desk, television, two chairs, a sofa, a lamp, and a window with a view.

A hotel room with a large bed, a nightstand, a lamp, a sofa, and a patterned pillow.

A breakfast buffet area with a display of cinnamon sweet rolls, a sign indicating the roll preparation method, and a patterned wall in the background.

5. Holiday Inn Express Le Claire Riverfront-Davenport by IHG

Le Claire

CNY736

CNY825 total

includes taxes & fees

Nov 1 - Nov 2

A modern lounge area with seating, tables, and large windows overlooking a body of water.

A modern hotel with multiple floors, large windows, and a parking lot with cars.

A modern kitchen with stainless steel appliances, a central island, and a seating area with a TV and lamp.

A bar area with multiple seating options, a television, and a well-stocked liquor shelf.

6. Hyatt House East Moline Quad Cities

East Moline

CNY622

CNY696 total

includes taxes & fees

Oct 25 - Oct 26

A Courtyard Inn with a covered entrance, multiple windows, and a parking lot.

A spacious lobby with a sofa, armchairs, a fireplace, a bookshelf, and a staircase.

A reception area with a wooden reception desk, a welcome mat, and a mirror reflecting the interior.

A modern kitchen with blue cabinets, a central island, and pendant lighting.

7. Country Inn & Suites by Radisson, Moline Airport

Moline

CNY450

CNY508 total

includes taxes & fees

Nov 11 - Nov 12

A modern lounge area with multiple seating options, large windows offering views of the water, and contemporary lighting fixtures.

A modern hotel lobby with a geometric wall design, seating area, and a view of the cityscape.

A modern lobby with a herringbone-patterned wall, a reception desk, and a seating area with a colorful rug.

A modern lobby with a fireplace, seating area, and a colorful abstract wall.

8. Hyatt Place East Moline Quad Cities

East Moline

CNY613

CNY686 total

includes taxes & fees

Oct 18 - Oct 19

A spacious indoor area with multiple seating options including sofas, chairs, and tables. There is a large window providing natural light and a view of greenery outside.

A hotel room with two beds, a desk, a TV, and a chair.

A modern Hampton Inn & Suites hotel with a large sign, a covered entrance, and an American flag.

A hotel reception area with a wooden reception desk, a 'Welcome to Hampton' sign, a food and beverage section, and patterned yellow chairs.

9. Hampton Inn & Suites Moline-Quad City Int'l Aprt

Moline

CNY620

CNY701 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk, a chair, a sofa, a lamp, and a picture frame on the wall.

A breakfast area with a coffee machine, yogurt dispenser, and various food items.

A hotel reception area with a modern design, including a reception desk, a seating area with a yellow chair, and a large window with a view of the outdoors.

A modern kitchen with blue cabinets, a wooden countertop, and a curved island.

10. Spark by Hilton Moline Quad Cities

Moline

CNY506

CNY572 total

includes taxes & fees

Oct 21 - Oct 22

An outdoor seating area with a fire feature, cushioned seating, and a stone wall.

A modern hotel lobby with a reception desk, seating areas, and a large window providing natural light.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A hotel room with a bed, a desk, a chair, a small table with a tray, and a TV mounted on the wall.

11. Springhill Suites BY Marriott Bettendorf

Bettendorf

CNY705

CNY824 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a stone fireplace, blue seating, and a modern design.

A modern lobby with a stone fireplace, blue seating, and framed wildlife pictures.

A window with a view of a parking lot and a body of water.

An indoor swimming pool with a clear blue water surface, a metal ladder, and a tiled edge.

12. Comfort Inn & Suites Riverview near Davenport and I-80

Le Claire

CNY774

CNY866 total

includes taxes & fees

Nov 1 - Nov 2

An electric vehicle charging station with multiple cables, a brick building in the background, and a small tree nearby.

A hotel room with a bed, a desk, a chair, a kitchenette, and a framed picture on the wall.

A hotel with a 'My Place' sign, a parking lot with several cars, and a bridge in the background.

13. My Place Hotel-East Moline/Quad Cities, IL

East Moline

CNY536

CNY601 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, a bedside table with a lamp, a large mirror, a bathroom with a bathtub, and a door.

A spacious room with a large window, a wooden door, and a reception desk.

Two front-loading washing machines in a laundry area with a granite countertop and beige walls.

A bathroom with a bathtub, toilet, and towel rack.

14. Super 8 by Wyndham East Moline

East Moline

CNY313

CNY347 total

includes taxes & fees

Oct 21 - Oct 22

A modern hotel lobby with a reception desk, seating area, and a large map mural.

A pool area with a clear view of the pool, a blue chair, and a clock on the wall.

A modern lounge area with a fireplace, comfortable seating, and large windows offering views.

A modern hotel lobby with a central seating area, multiple tables, and contemporary lighting fixtures.

15. Holiday Inn Express Moline - Quad Cities Area by IHG

Moline

CNY623

CNY704 total

includes taxes & fees

Nov 15 - Nov 16

A modern kitchen with a long island, bar stools, and pendant lighting.

A bar area with a long counter, multiple shelves of bottles, and several chairs.

A large hotel with a central courtyard, a parking lot, and a river in the background.

A spacious lobby with a reception desk, a large abstract artwork on the wall, and a modern design with wooden accents.

16. Wyndham Moline on John Deere Commons

Moline

CNY584

CNY659 total

includes taxes & fees

Nov 2 - Nov 3

A restaurant with multiple tables and chairs, a kitchen area, and a counter with various items.

A hotel room with two beds, a nightstand with a lamp, and three framed pictures on the wall.

A gym with various exercise equipment including treadmills, an elliptical, and a bench.

A reception area with a dark wood reception desk, a waiting area with a sofa and chairs, and a reception counter with a sign reading "Quality Inn & Suites by Choice Hotels".

17. Quality Inn & Suites Moline - Quad Cities

Moline

CNY401

CNY453 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a high ceiling, a reception desk, a seating area with a sofa and chairs, and a large globe on a table.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A spacious lobby with red armchairs, a glass-top coffee table, and a patterned carpet.

A compact hotel room with a kitchenette, a flat-screen TV, a sofa, and a lamp.

18. Best Western Annawan Inn

Annawan

CNY618

CNY686 total

includes taxes & fees

Oct 22 - Oct 23

An outdoor seating area with wicker furniture and a central fire feature, surrounded by glass doors and a building with multiple windows.

A modern hotel with a flat facade, multiple windows, and a covered entrance area.

A modern bar area with a counter, bar stools, and a refrigerated display.

A hotel room with a sofa, armchair, ottoman, desk, and a large window.

19. Courtyard by Marriott Bettendorf

Bettendorf

CNY734

CNY822 total

includes taxes & fees

Oct 18 - Oct 19

A lobby with a stone fireplace, seating area, and a snack bar with shelves.

A lobby with a stone fireplace, blue seating, and a refrigerator stocked with beverages.

An indoor swimming pool with a wooden wall and tiled floor.

20. MainStay Suites LeClaire - Quad Cities

Le Claire

CNY792

CNY887 total

includes taxes & fees

Nov 15 - Nov 16

View all properties

Go beyond your typical stay in Osco

Check out reviews of Osco hotels guests love

Holiday Inn Express Moline - Quad Cities Area by IHG

Moline

10/10 Exceptional

Alisa

Holiday Inn Express Le Claire Riverfront-Davenport by IHG

Le Claire

10/10 Exceptional

Lise

Hyatt House East Moline Quad Cities

East Moline

10/10 Exceptional

Chang

Residence Inn Marriott Moline

Moline

10/10 Exceptional

Malissa

An outdoor patio with wicker furniture, a fire feature, and string lights.

A modern kitchen with built-in appliances, a central island with storage, and a view of the outdoors.

A Holiday Inn Express hotel with a modern facade, large windows, and a covered entrance area.

Holiday Inn Express Bettendorf Davenport NE by IHG

Bettendorf

10/10 Exceptional

Jeremy

My Place Hotel-East Moline/Quad Cities, IL

East Moline

10/10 Exceptional

Danel

Best Western Geneseo Inn

Geneseo

10/10 Exceptional

Sometimes I stay at this hotel when I am visiting family in the Geneseo area.The hotel is clean, well kept, quiet and I feel safe staying there alone. Although I don't know for sure, I think the Geneseo, Illinois BW is family run. Any family that I have encountered while there, including the small children, are polite and attentive to guests. The hotel is located in a good area for food, shopping and close to the highway for travelers. In spite of the COVID-19 restrictions, the Geneseo, Illinois...

KimM

Comfort Inn & Suites East Moline near I-80

East Moline

10/10 Exceptional

Dick

Hampton Inn & Suites Moline-Quad City Int'l Aprt

Moline

10/10 Exceptional

Pastor Richard

Comfort Inn & Suites Riverview near Davenport and I-80

Le Claire

10/10 Exceptional

craig

A modern kitchen with a central island stocked with fruits, beverages, and condiments.

A modern interior with a seating area, a large flat-screen TV, and a colorful wall art piece.

A hotel room with a wooden ceiling, a bed, a desk with a lamp, a sofa with cushions, and artwork on the wall.

Element by Marriott Moline

Moline

10/10 Exceptional

Steph

Regency Inn Geneseo

Geneseo

10/10 Exceptional

Barbara

Wyndham Moline on John Deere Commons

Moline

10/10 Exceptional

Kim

A reception desk with a wooden finish, a digital screen, and a sign indicating the name 'Marriott Bonvoy'.

A hotel room with two beds, a nightstand with a phone and remote, and a wall-mounted light fixture.

A modern lounge area with seating, a fireplace, and a television.

Fairfield Inn & Suites by Marriott Davenport Quad Cities

Davenport

10/10 Exceptional

Rhonda

An outdoor seating area with wicker furniture and a fire feature, overlooking a brick building with large windows.

A modern hotel room with a large bed, a desk with a flat-screen TV, a sofa, and a small ottoman.

An indoor swimming pool with wooden ceiling beams, tiled walls, and multiple chairs and tables along the poolside.

A modern restaurant with a long counter, bar stools, and wooden shelves.

Home2 Suites by Hilton Bettendorf Quad Cities

Bettendorf

10/10 Exceptional

Steve

A hotel room with two beds, a TV, a window with blinds, a framed picture on the wall, and a bedside lamp.

A row of white, modern, front-loading washing machines in a clean, white-walled laundry room.

A modern restaurant with a bar area, seating arrangements, and a kitchen in the background.

My Place Hotel - Davenport/Quad Cities IA

Davenport

10/10 Exceptional

Anonymous traveler

Frequently Asked Questions

How much does a hotel room cost in Osco?

You can discover great hotels in Osco from CNY312 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Osco that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Osco hotels?

Discover great deals on Osco hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Osco hotels.

Can I book Osco hotels with free cancellation?

It's easy to book a refundable Osco hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Keep exploring

Lodging