Hotels in East Prairie

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Check prices for these dates

Tonight
Nov 18 - Nov 19
Tomorrow
Nov 19 - Nov 20
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Where to stay in East Prairie?

Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
2.5 star property
6.8 out of 10, (406)
The price is CNY467
CNY518 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in East Prairie

Big Oak Tree State Park

3.8/5 (8 reviews)
Big Oak Tree State Park is 10.3 mi (16.6 km) from central East Prairie, why not stop by during your stay.
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Learn more about East Prairie

East Prairie is well-known for its attractions such as Big Oak Tree State Park and Mississippi River.

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Bridge over Mississippi River, New Orleans in background

Check out reviews of East Prairie hotels guests love

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Staff are wonderful, kind and welcoming! The happy hour is a great way to get out of your room and socialize. Lots of yummy food and drinks. "
Kara 1-night trip
Posted 14 hours ago
Drury Inn & Suites Sikeston, MO

Frequently asked questions

What hotels do travelers like in East Prairie?
Guests like Quality Inn Charleston - Sikeston.
Can I book a refundable hotel in East Prairie?
If you need the flexibility to change your travel plans to East Prairie, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in East Prairie be like during my trip?
July and August are typically the warmest months in East Prairie when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. March and April are the months with the most rain.
Why should I book my East Prairie accommodation with Hotels.com?
There are lots of reasons to book your East Prairie trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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