Hotels in Cayuse

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

This weekend
Next weekend

Where to stay in Cayuse?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Cayuse

Learn more about Cayuse

The region around Cayuse is home to attractions such as Wildhorse Casino and Pendleton Woolen Mills.

Frequently asked questions

What hotels do travelers like in Cayuse?
Can I book a refundable accommodation in Cayuse?
If you want the flexibility to change your travel plans to Cayuse, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Cayuse be like during my visit?
The warmest months in Cayuse are usually July and August with an average temp of 70°F. December and January are the chilliest months when the average temp is 36°F. The rainiest months are December and March.
Why should I book my Cayuse hotel with Hotels.com?
There are plenty of reasons to book your Cayuse travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.