Hotels in Williamsville

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Top 5 hotels in Williamsville at a glance

Lake Wappapello — 2-star hotel in Williamsville. Guest rating: 9.2/10 — Wonderful.
Motel 6 Poplar Bluff, MO — 2-star hotel in Poplar Bluff. Guest rating: 8.0/10 — Very Good.
Hampton Inn Poplar Bluff — 2.5-star hotel in Poplar Bluff. Guest rating: 9.4/10 — Exceptional.
Fairfield Inn & Suites by Marriott Poplar Bluff — 3-star hotel in Poplar Bluff. Guest rating: 9.4/10 — Exceptional.
Drury Inn & Suites Poplar Bluff — 3-star hotel in Poplar Bluff. Guest rating: 9.4/10 — Exceptional.

Where to stay in Williamsville?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Williamsville on Hotels.com. These Williamsville hotels consistently deliver on comfort, location and traveler experience. Last updated on August 26, 2026.

Lake Wappapello

Williamsville

CNY514

CNY542 total

includes taxes & fees

Sep 7 - Sep 8

Blackout drapes, WiFi (free), bed sheets

Motel 6 Poplar Bluff, MO

Poplar Bluff

CNY531

CNY595 total

includes taxes & fees

Sep 7 - Sep 8

Hampton Inn Poplar Bluff

Poplar Bluff

CNY628

CNY704 total

includes taxes & fees

Sep 13 - Sep 14

Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

CNY680

CNY768 total

includes taxes & fees

Sep 7 - Sep 8

Suite, 2 Queen Beds, Accessible (Sofa Sleeper, Tub, 2 Rooms) | Desk, blackout drapes, iron/ironing board, cribs (free)

Drury Inn & Suites Poplar Bluff

Poplar Bluff

CNY632

CNY714 total

includes taxes & fees

Sep 13 - Sep 14

Holiday Inn Poplar Bluff by IHG

Poplar Bluff

CNY565

CNY638 total

includes taxes & fees

Sep 13 - Sep 14

Desk, rollaway beds (surcharge), WiFi (free), alarm clocks

Suite, 1 King Bed, Non Smoking | Desk, rollaway beds (surcharge), WiFi (free), alarm clocks

Comfort Inn Poplar Bluff North

Poplar Bluff

CNY542

CNY612 total

includes taxes & fees

Sep 20 - Sep 21

In-room safe, desk, WiFi (free), bed sheets

Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

CNY371

CNY420 total

includes taxes & fees

Sep 10 - Sep 11

Sam A Baker State Park

Patterson

CNY1,180

CNY1,250 total

includes taxes & fees

Aug 30 - Aug 31

View all properties

Go beyond your typical stay in Williamsville

Pet friendly

Pool

Check out reviews of Williamsville hotels guests love

Drury Inn & Suites Poplar Bluff

10/10 Excellent

"It feels safe and the staff is amazing! You feel heard and taken care of , great rooms great amenities!"

Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent

"loved it!!!"

Hampton Inn Poplar Bluff

10/10 Excellent

"We travel frequently and this is a place we have enjoyed when in this area. We have stayed here several times"

Holiday Inn Poplar Bluff by IHG

8/10 Good

"The room was clean but other parts like the elevator were very dirty. Staff were amazing"

Motel 6 Poplar Bluff, MO

8/10 Good

"Clean and nice."

Frequently asked questions

How much does a hotel room cost in Williamsville?

You can find top hotels in Williamsville from CNY420 with options to suit your budget and needs. If you're looking for an affordable hotel in Williamsville that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Williamsville hotels?

Discover great deals on Williamsville hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Williamsville hotels.

Can I book Williamsville hotels with free cancellation?

In order to book a refundable Williamsville hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book a refundable hotel in Williamsville?

If you want the flexibility to change your plans to Williamsville, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Williamsville be like during my vacation?

July and August are typically the warmest months in Williamsville when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and May are the months with the most rain.

Why should I book my Williamsville hotel with Hotels.com?

There are lots of reasons to book your Williamsville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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