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Hotels in Mesquite

October 2026
14
November 2026

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This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Where to stay in Mesquite?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Mesquite on Hotels.com. These Mesquite hotels consistently deliver on quality, location and traveler experience. Last updated on October 14, 2026.
A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.
An indoor swimming pool with clear water, tiled edges, and a metal safety railing.
A hotel with a modern facade, multiple parking spaces, and a well-lit entrance.
A gym with treadmills, elliptical machines, and exercise bikes.

1. Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
Las Cruces
CNY791
CNY913 total
includes taxes & fees
Oct 24 - Oct 25
Hampton Inn & Suites Las Cruces I-10
A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.
A breakfast buffet with various food items, including fruits, pastries, and hot beverages.
A hotel with a distinctive arched entrance and a clear sign reading "Hilton Garden Inn."
An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

2. Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
Las Cruces
CNY734
CNY849 total
includes taxes & fees
Oct 31 - Nov 1
Hilton Garden Inn Las Cruces
A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.
A hotel room with a large bed, a desk, a chair, a flat-screen TV, and a window with curtains.
A modern hotel room with a blue sofa, armchairs, a flat-screen TV, and framed pictures on the wall.
An indoor swimming pool with clear water, a diving board, and lounge chairs.

3. Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
Las Cruces
CNY557
CNY648 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Suites University Las Cruces
An outdoor patio area with seating arrangements, including sofas and chairs, under a covered structure with a wooden ceiling.
A modern hotel lobby with a large sofa, armchairs, a coffee table, and a TV.
A modern coffee shop interior with a wooden counter, seating area, and menu boards.
A modern bar area with a long counter, bar stools, and a variety of liquor bottles.

4. Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
Las Cruces
CNY1,018
CNY1,171 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard by Marriott Las Cruces at NMSU
A pool area with a hot tub, lounge chairs, and a lifeguard stand.
A hotel room with a blue accent wall, a sofa, a bed, a desk, and a mirror.
A modern lobby with a sofa set, a small table with a potted plant, and a patterned wall.
A spacious living area with a fireplace, a television mounted above it, and a seating arrangement including a sofa and chairs.

5. Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
Las Cruces
CNY691
CNY824 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Suites Las Cruces I-25 North
A spacious indoor courtyard with tiled flooring, wooden furniture, and a balcony with a railing.
A dining area with a table and chairs, a remote control on a rug, and a door leading to another room.
An indoor swimming pool with tiled flooring, a metal pool ladder, and a few lounge chairs.
A hotel room with a large bed, a television, a desk, and a chair.

6. Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
Las Cruces
CNY512
CNY596 total
includes taxes & fees
Oct 18 - Oct 19
Ramada Hotel & Conference Center by Wyndham Las Cruces
A pool area with a fountain, palm trees, and outdoor seating.
A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.
A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.
A fountain with a lotus design in a pool, surrounded by a balustrade and palm trees.

7. Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
Las Cruces
CNY715
CNY1,008 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Encanto de Las Cruces
A lobby with a stone fireplace, sofas, and a glass coffee table.
An indoor swimming pool with a hot tub, tiled flooring, and a high ceiling with beams.
A courtyard with outdoor seating, a small tree, and a stone wall.
A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.

8. Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
Las Cruces
CNY709
CNY821 total
includes taxes & fees
Oct 25 - Oct 26
Drury Inn & Suites Las Cruces
A hotel room with two beds, a desk with a TV, a chair, and two lamps.
A living room with striped sofas, a glass coffee table, a fireplace, and a television.
A kitchen with a wooden counter, coffee machines, a microwave, and various appliances.
A multi-story hotel with a central entrance, balconies, and a parking area.

9. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Las Cruces
CNY392
CNY461 total
includes taxes & fees
Nov 8 - Nov 9
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
An outdoor seating area with a fire pit, sofas, and chairs.
A modern hotel room with a wooden desk, a grey sofa, a small ottoman, a television, and a bed with a white headboard.
A modern hotel room with a large bed, a desk with a computer, a television, and a kitchenette.
A modern lounge area with a sofa, chairs, and tables, featuring pendant lighting and large windows.

10. Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
Las Cruces
CNY839
CNY968 total
includes taxes & fees
Oct 31 - Nov 1
Home2 Suites by Hilton Las Cruces
A buffet area with a variety of baked goods, a coffee station, and a decorative plant.
A patio with a table and chairs, a large tree, a fountain, and a pool in the background.
A hotel room with two beds, wooden benches, a desk, and a chair.
Lobby

11. Best Western Mission Inn

Best Western Mission Inn
Las Cruces
CNY536
CNY625 total
includes taxes & fees
Oct 21 - Oct 22
Best Western Mission Inn
A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.
A modern hotel with a flat roof, large windows, and a well-lit entrance.
A compact kitchenette with a microwave, a small sink, and a refrigerator.
A pool area with lounge chairs and umbrellas, surrounded by a fence and a building with multiple windows and balconies.

12. Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
Las Cruces
CNY747
CNY864 total
includes taxes & fees
Oct 18 - Oct 19
Springhill Suites By Marriott Las Cruces
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.
A spacious living area with a fireplace, comfortable seating, and a television.
A hotel room with a sofa, a dining table, a kitchen area with a microwave, refrigerator, and sink.
A swimming pool with lounge chairs and a sunshade.

13. Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
Las Cruces
CNY763
CNY882 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn & Suites Las Cruces I-25
A Days Inn with a large sign, a flag, and a well-maintained entrance area.
A hotel room with a bed, desk, chair, and a painting on the wall.
An outdoor patio with wooden benches and a grill area.
A breakfast bar with coffee machines, a fruit bowl, and stacked paper cups.

14. Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
Las Cruces
CNY324
CNY384 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn by Wyndham Las Cruces
A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.
A hotel dining area with multiple tables and chairs, a coffee station, and a reception desk.
A golf course with a mountain range in the background.
A hotel room with a large bed, a television, a desk, and a chair.

15. Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
Las Cruces
CNY658
CNY762 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Las Cruces Mesilla
A living room with a sofa, two armchairs, a coffee table, and a lamp.
A spacious lobby with a wooden floor, a reception desk, and a staircase with a green wall featuring a white leaf pattern.
A spacious lobby with a wooden staircase, a seating area with two armchairs and a table, and a green wall with a leaf pattern.
A hotel room with a bed, a desk with a television, a chair, and a wardrobe.

16. Sleep Inn University

Sleep Inn University
Las Cruces
CNY395
CNY463 total
includes taxes & fees
Nov 5 - Nov 6
Sleep Inn University
An outdoor patio area with wicker furniture, a barbecue grill, and a stone wall.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A breakfast bar with a red wall, wooden cabinets, and various breakfast items.
A pool area with blue chairs and a no diving sign.

17. Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces
Las Cruces
CNY777
CNY898 total
includes taxes & fees
Nov 1 - Nov 2
Towneplace Suites by Marriott Las Cruces
A hotel room with a bathtub, a sofa, a bed, a desk, and a television.
A room with a ceiling fan, a framed painting, a sofa, a desk, a chair, and a small kitchenette.
A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.
A conference room with multiple tables, chairs, and a carpeted floor.

18. Holiday Inn Express Hotel and Suites Las Cruces by IHG

Holiday Inn Express Hotel and Suites Las Cruces by IHG
Las Cruces
CNY649
CNY751 total
includes taxes & fees
Nov 3 - Nov 4
Holiday Inn Express Hotel and Suites Las Cruces by IHG
A hotel lobby with a 'Connect & Print' service area, a fireplace, and a seating area with blue chairs.
A hallway with two refrigerated beverage dispensers stocked with various drinks and snacks.
A modern office space with multiple desktop computers, a coffee machine, and a colorful carpet.
A lobby with a stone wall, a fireplace, and blue chairs.

19. Fairfield Inn by Marriott Las Cruces

Fairfield Inn by Marriott Las Cruces
Las Cruces
CNY863
CNY1,019 total
includes taxes & fees
Nov 3 - Nov 4
Fairfield Inn by Marriott Las Cruces
A multi-story building with a stone facade, a central entrance with a wooden archway, and a blue car parked in front.
A restaurant with a bar area, wooden chairs, a round table, and wall art.
A hotel lobby with multiple seating areas, including round tables and sofas, a bar area with a television, and a large window with curtains.
A swimming pool with a curved edge, surrounded by palm trees and a building with a tiled roof.

20. Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
Las Cruces
CNY743
CNY859 total
includes taxes & fees
Nov 1 - Nov 2
Staybridge Suites Las Cruces by IHG
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Go beyond your typical stay in Mesquite

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Check out reviews of Mesquite hotels guests love

A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.
A breakfast buffet with various food items, including fruits, pastries, and hot beverages.
A hotel with a distinctive arched entrance and a clear sign reading "Hilton Garden Inn."
An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
Las Cruces

10/10 Exceptional

United States
Amy
Hilton Garden Inn Las Cruces
A lobby with a stone fireplace, sofas, and a glass coffee table.
An indoor swimming pool with a hot tub, tiled flooring, and a high ceiling with beams.
A courtyard with outdoor seating, a small tree, and a stone wall.
A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
Las Cruces

10/10 Exceptional

United States
Robert
Drury Inn & Suites Las Cruces
A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.
An indoor swimming pool with clear water, tiled edges, and a metal safety railing.
A hotel with a modern facade, multiple parking spaces, and a well-lit entrance.
A gym with treadmills, elliptical machines, and exercise bikes.

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
Las Cruces

10/10 Exceptional

United States
Anonymous traveler
Hampton Inn & Suites Las Cruces I-10
A pool area with a fountain, palm trees, and outdoor seating.
A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.
A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.
A fountain with a lotus design in a pool, surrounded by a balustrade and palm trees.

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
Las Cruces

10/10 Exceptional

United States
Jeremy
Hotel Encanto de Las Cruces
An outdoor seating area with a fire pit, sofas, and chairs.
A modern hotel room with a wooden desk, a grey sofa, a small ottoman, a television, and a bed with a white headboard.
A modern hotel room with a large bed, a desk with a computer, a television, and a kitchenette.
A modern lounge area with a sofa, chairs, and tables, featuring pendant lighting and large windows.

Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
Las Cruces

10/10 Exceptional

United States
FERNANDO
Home2 Suites by Hilton Las Cruces
A buffet area with a variety of baked goods, a coffee station, and a decorative plant.
A patio with a table and chairs, a large tree, a fountain, and a pool in the background.
A hotel room with two beds, wooden benches, a desk, and a chair.
Lobby

Best Western Mission Inn

Best Western Mission Inn
Las Cruces

10/10 Exceptional

United States
Deanna
Best Western Mission Inn
A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.
A hotel room with a large bed, a desk, a chair, a flat-screen TV, and a window with curtains.
A modern hotel room with a blue sofa, armchairs, a flat-screen TV, and framed pictures on the wall.
An indoor swimming pool with clear water, a diving board, and lounge chairs.

Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
Las Cruces

10/10 Exceptional

United States
Beatriz
Comfort Suites University Las Cruces
A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.
A modern hotel with a flat roof, large windows, and a well-lit entrance.
A compact kitchenette with a microwave, a small sink, and a refrigerator.
A pool area with lounge chairs and umbrellas, surrounded by a fence and a building with multiple windows and balconies.

Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
Las Cruces

10/10 Exceptional

United States
Cynthia
Springhill Suites By Marriott Las Cruces
A hotel room with two beds, a desk with a TV, a chair, and two lamps.
A living room with striped sofas, a glass coffee table, a fireplace, and a television.
A kitchen with a wooden counter, coffee machines, a microwave, and various appliances.
A multi-story hotel with a central entrance, balconies, and a parking area.

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Las Cruces

10/10 Exceptional

United States
Wendy
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
A spacious living room with a dark wooden coffee table, patterned armchairs, a grey sofa, and a red and orange patterned rug.
A hotel room with a bed, a sofa, a desk, and a nightstand.
A reception desk with a dark wood finish, a flat-screen TV mounted above it, and a sign indicating check-in/out procedures.
A spacious dining area with multiple tables and chairs, a kitchen in the background, and a large screen on the wall.

Best Western Anthony/West El Paso

Best Western Anthony/West El Paso
Anthony

10/10 Exceptional

United States
Merci
Best Western Anthony/West El Paso
A modern breakfast bar with a coffee machine, cereal and fruit options, and a yogurt, eggs, and milk dispenser.
A large, modern building with a curved roof and large glass windows, likely a hotel or conference center.
A reception area with two reception desks, a blue geometric wall design, and a sign for 'Holiday Inn Express & Suites'.
A hotel room with a blue sofa, a wooden coffee table, two beds with white bedding, a headboard with a blue accent, a framed picture on the wall, and a window with a geometric blind.

Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
Las Cruces

10/10 Exceptional

United States
Phil
Holiday Inn Express & Suites Las Cruces North by IHG
An outdoor patio area with wicker furniture, a barbecue grill, and a stone wall.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A breakfast bar with a red wall, wooden cabinets, and various breakfast items.
A pool area with blue chairs and a no diving sign.

Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces
Las Cruces

10/10 Exceptional

United States
Marisa
Towneplace Suites by Marriott Las Cruces
A hotel lobby with a 'Connect & Print' service area, a fireplace, and a seating area with blue chairs.
A hallway with two refrigerated beverage dispensers stocked with various drinks and snacks.
A modern office space with multiple desktop computers, a coffee machine, and a colorful carpet.
A lobby with a stone wall, a fireplace, and blue chairs.

Fairfield Inn by Marriott Las Cruces

Fairfield Inn by Marriott Las Cruces
Las Cruces

10/10 Exceptional

United States
Shirley
Fairfield Inn by Marriott Las Cruces
A Days Inn with a large sign, a flag, and a well-maintained entrance area.
A hotel room with a bed, desk, chair, and a painting on the wall.
An outdoor patio with wooden benches and a grill area.
A breakfast bar with coffee machines, a fruit bowl, and stacked paper cups.

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
Las Cruces

10/10 Exceptional

United States
Robert
Days Inn by Wyndham Las Cruces
A multi-story building with a stone facade, a central entrance with a wooden archway, and a blue car parked in front.
A restaurant with a bar area, wooden chairs, a round table, and wall art.
A hotel lobby with multiple seating areas, including round tables and sofas, a bar area with a television, and a large window with curtains.
A swimming pool with a curved edge, surrounded by palm trees and a building with a tiled roof.

Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
Las Cruces

10/10 Exceptional

United States
Marcella
Staybridge Suites Las Cruces by IHG

Frequently Asked Questions

How much does a hotel room cost in Mesquite?

You can find top hotels in Mesquite from CNY324 with options to suit your budget and needs. If you're looking for an affordable hotel in Mesquite that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Mesquite hotels?

Discover great deals on Mesquite hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Mesquite hotels.

Can I book Mesquite hotels with free cancellation?

To book a refundable Mesquite hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

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