Hotels in Center

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Oct 30 - Oct 31
Tomorrow
Oct 31 - Nov 1
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Where to stay in Center?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Center on Hotels.com. These Center hotels consistently deliver on quality, location and traveler experience. Last updated on October 30, 2026.
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

1. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1,001 reviews)
Escape to this welcoming Hannibal retreat with an indoor pool and fitness center for active travelers. Free breakfast, WiFi, and parking enhance your stay while Hospital Park and Veteran's Sports Park await nearby. Comfortable beds and helpful staff ensure a pleasant experience.
The price is CNY701
CNY815 total
includes taxes & fees
Nov 25 - Nov 26
Sleep Inn & Suites Hannibal West
A hotel room with a bed, a sofa, a desk, and a lamp.

2. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
Hannibal
7.6 out of 10, Good, (770 reviews)
Wake up refreshed with a complimentary breakfast before exploring nearby West Ely Park and Sodalis Nature Preserve. After sightseeing in Hannibal, unwind in the indoor pool or maintain your routine at the 24-hour fitness center.
The price is CNY515
CNY614 total
includes taxes & fees
Nov 25 - Nov 26
Comfort Inn & Suites - Hannibal
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

3. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very good, (1,009 reviews)
Wake up to complimentary breakfast at this convenient Hannibal hotel before exploring nearby Hospital Park. The indoor pool and hot tub offer year-round relaxation, while free WiFi and parking add value to your stay. Friendly staff ensure a comfortable visit.
The price is CNY528
CNY614 total
includes taxes & fees
Nov 23 - Nov 24
Quality Inn & Suites Hannibal West
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

4. Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.6 out of 10, Excellent, (1,001 reviews)
Just 5 minutes from the Mississippi River, this hotel offers indoor and outdoor pools plus a hot tub for relaxation. Walk to Mark Twain's Boyhood Home and other historic sites. Quiet rooms include refrigerators and microwaves, with free parking and breakfast to start your day.
The price is CNY786
CNY907 total
includes taxes & fees
Nov 26 - Nov 27
Best Western On The River
A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

5. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
Hannibal
7.2 out of 10, Good, (1,001 reviews)
Experience tranquility at this peaceful Hannibal motel offering a seasonal pool and garden terrace. Enjoy complimentary breakfast, WiFi, and parking while hiking nearby trails. Conveniently located near Indian Mounds Park with clean rooms and exceptionally helpful staff.
The price is CNY418
CNY482 total
includes taxes & fees
Nov 26 - Nov 27
Super 8 by Wyndham Hannibal
A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.

6. FairBridge Inn Express, Monroe City

FairBridge Inn Express, Monroe City
2.0 star property
Monroe City
8.4 out of 10, Very good, (494 reviews)
This friendly Missouri motel welcomes travelers with free WiFi and self-serve morning meals from 6:30-9:00 AM. Park without charge and enjoy a comfortable business-friendly atmosphere during your Monroe City stay.
The price is CNY600
CNY651 total
includes taxes & fees
Nov 30 - Dec 1
FairBridge Inn Express, Monroe City
A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

7. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
Hannibal
7.4 out of 10, Good, (1,000 reviews)
The price is CNY386
CNY446 total
includes taxes & fees
Nov 7 - Nov 8
Motel 6 Hannibal, MO
A hotel room with two beds, a wooden headboard, a nightstand with a phone, and a wall-mounted lamp.

8. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (294 reviews)
Enjoy complimentary breakfast, WiFi, and parking at this conveniently located Hannibal hotel. Just a short drive from Mississippi River, West Ely Park, and Sodalis Nature Preserve, this friendly accommodation earns consistent praise for its attentive staff.
The price is CNY460
CNY530 total
includes taxes & fees
Nov 7 - Nov 8
Days Inn by Wyndham Hannibal
An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

9. Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
Hannibal
6.4 out of 10, Good, (828 reviews)
Near the banks of the mighty Mississippi, this Hannibal hotel offers a complimentary hot breakfast and free parking. Take a refreshing dip in the indoor pool, visit the health club, or explore West Ely Park and Sodalis Nature Preserve just minutes away.
The price is CNY368
CNY427 total
includes taxes & fees
Nov 26 - Nov 27
Baymont by Wyndham Hannibal
A park with a pond, picnic tables, and a gazebo.

10. Cannon Dam Cabins

Cannon Dam Cabins
3.0 star property
Perry
9.4 out of 10, Exceptional, (26 reviews)
Enjoy a peaceful retreat in Perry with your own private patio and convenient microwave. The indoor pool offers year-round relaxation, while Robert E Allen Recreation Area and Perry Park await just minutes away for outdoor adventures.
The price is CNY684
CNY728 total
includes taxes & fees
Nov 7 - Nov 8
Cannon Dam Cabins
A red barn with a balcony, a hammock, and outdoor seating.

11. Kennedys Red Barn Inn

Kennedys Red Barn Inn
2.5 star property
Perry
9.2 out of 10, Wonderful, (30 reviews)
Nestled in Perry near Robert E Allen Recreation Area, this charming B&B offers free breakfast, WiFi, and parking. Unwind in the hot tub after exploring local attractions or maintain your routine at the fitness center.
The price is CNY609
CNY648 total
includes taxes & fees
Nov 30 - Dec 1
Kennedys Red Barn Inn
A hotel room with two beds, a nightstand, and a lamp.

12. The Junction Inn

The Junction Inn
2.0 star property
Perry
6.4 out of 10, Good, (48 reviews)
This welcoming hotel offers convenient amenities just minutes from Bill Trower Memorial Park. Enjoy complimentary WiFi and parking while the 24-hour front desk ensures your needs are met at any hour of your stay.
The price is CNY445
CNY474 total
includes taxes & fees
Nov 20 - Nov 21
The Junction Inn
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

13. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (204 reviews)
Escape to this intimate guesthouse set just a 5-minute walk from the Mississippi River. Enjoy free WiFi and parking while exploring nearby Planters Barn Theater and Mark Twain Boyhood Home and Museum. Netflix awaits after your day of adventures.
The price is CNY1,001
CNY1,386 total
includes taxes & fees
Nov 9 - Nov 10
Riverside Inn Hannibal
A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

14. Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
Hannibal
7.4 out of 10, Good, (187 reviews)
Escape to this welcoming Hannibal hotel with free WiFi and parking, just moments from West Ely Park and Sodalis Nature Preserve. Take a refreshing dip in the indoor pool after exploring nearby Mark Twain attractions, then relax in clean, comfortable rooms.
The price is CNY402
CNY466 total
includes taxes & fees
Nov 30 - Dec 1
Howard Johnson BY Wyndham Hannibal
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

15. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
8.8 out of 10, Excellent, (47 reviews)
Immerse yourself in literary heritage at this modern aparthotel, just minutes from Mark Twain Memorial Lighthouse and Hannibal's historic sites. Smart rooms feature hydromassage showers and plush down comforters, while free parking and WiFi enhance the 4-star experience.
The price is CNY1,062
CNY1,456 total
includes taxes & fees
Nov 1 - Nov 2
Lighthouse Inn & Suites
A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

16. Garden House Bed and Breakfast

Garden House Bed and Breakfast
3.0 star property
Hannibal
8.4 out of 10, Very good, (57 reviews)
Unwind at this inviting B&B close to Big River Train Town and Jim's Journey: The Huck Finn Freedom Center. Free parking and wired internet complement comfortable rooms with bathrobes, while nearby hiking trails beckon outdoor enthusiasts.
The price is CNY711
CNY820 total
includes taxes & fees
Oct 31 - Nov 1
Garden House Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Go beyond your typical stay in Center

pet friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool

Check out reviews of Center hotels guests love

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal

10/10 Exceptional

This motel was nice but I had asked to be with ball team in same area then we found out everyone was spread out
United States
Linda D
Reviewed June 23, 2024
Sleep Inn & Suites Hannibal West

Frequently Asked Questions

How much does a hotel room cost in Center?

You can find top hotels in Center from CNY368 with options to suit your budget and needs. If you're after an affordable hotel in Center that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Center hotels?

Discover great deals on Center hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Center hotels.

Can I book Center hotels with free cancellation?

To book a refundable Center hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.