Hotels in South Roxana

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Where to stay in South Roxana?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in South Roxana on Hotels.com. These South Roxana hotels consistently deliver on comfort, location and traveler experience. Last updated on August 13, 2026.

1. Holiday Inn Express & Suites Edwardsville by IHG

Edwardsville

CNY823

CNY946 total

includes taxes & fees

Aug 31 - Sep 1

In-room safe, laptop workspace, iron/ironing board, cribs (free)

2. Comfort Inn Edwardsville - St. Louis

Edwardsville

CNY642

CNY738 total

includes taxes & fees

Sep 3 - Sep 4

Blackout drapes, cribs (free), rollaway beds (surcharge), WiFi (free)

3. Country Hearth Inn & Suites Edwardsville St. Louis

Edwardsville

CNY735

CNY845 total

includes taxes & fees

Aug 24 - Aug 25

Room, 1 Queen Bed, Jetted Tub | Blackout drapes, WiFi (free), bed sheets

4. Red Lion Inn & Suites Pontoon Beach

Granite City

CNY486

CNY550 total

includes taxes & fees

Aug 16 - Aug 17

5. The Great Rivers, an Ascend Collection Hotel

Alton

CNY699

CNY797 total

includes taxes & fees

Sep 7 - Sep 8

In-room safe, desk, iron/ironing board, WiFi (free)

6. Hampton Inn & Suites St. Louis/Alton

Alton

CNY880

CNY1,002 total

includes taxes & fees

Aug 30 - Aug 31

Hypo-allergenic bedding available, pillowtop beds, desk, blackout drapes

7. Best Western Plus Parkway Hotel

Alton

CNY596

CNY680 total

includes taxes & fees

Aug 20 - Aug 21

8. Drury Inn & Suites St. Louis Collinsville

Eastport

CNY749

CNY861 total

includes taxes & fees

Aug 27 - Aug 28

Desk, iron/ironing board, WiFi (free), bed sheets

9. Best Western Troy Hotel

Troy

CNY601

CNY667 total

includes taxes & fees

Aug 26 - Aug 27

Suite, 2 Queen Beds, Non Smoking | Down comforters, in-room safe, desk, blackout drapes

Suite, 1 King Bed, Non Smoking | Down comforters, in-room safe, desk, blackout drapes

10. Comfort Inn Collinsville near St. Louis

Eastport

CNY637

CNY732 total

includes taxes & fees

Aug 30 - Aug 31

11. Holiday Inn Express Troy by IHG

Troy

CNY742

CNY823 total

includes taxes & fees

Aug 30 - Aug 31

12. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Eastport

CNY608

CNY699 total

includes taxes & fees

Sep 14 - Sep 15

Standard Room, 2 Queen Beds | Desk, laptop workspace, iron/ironing board, cribs (free)

Desk, laptop workspace, iron/ironing board, cribs (free)

13. Super 8 by Wyndham Troy IL/St. Louis Area

Troy

CNY459

CNY509 total

includes taxes & fees

Aug 20 - Aug 21

Room, 2 Queen Beds | Desk, blackout drapes, iron/ironing board, rollaway beds (surcharge)

14. Pear Tree Inn St. Louis Airport

St. Ann

CNY607

CNY715 total

includes taxes & fees

Aug 19 - Aug 20

15. Hyatt Select St. Louis Airport

Woodson Terrace

CNY749

CNY920 total

includes taxes & fees

Aug 30 - Aug 31

16. Hampton Inn & Suites St. Louis at Forest Park

Dogtown

CNY879

CNY1,037 total

includes taxes & fees

Aug 23 - Aug 24

Desk, laptop workspace, blackout drapes, iron/ironing board

17. Red Roof Inn St Louis - Troy, IL

Troy

CNY486

CNY539 total

includes taxes & fees

Sep 13 - Sep 14

Desk, blackout drapes, iron/ironing board, cribs (free)

18. Drury Inn & Suites St. Louis Airport

Edmundson

CNY776

CNY910 total

includes taxes & fees

Aug 30 - Aug 31

Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, cribs (free)

19. Wingate by Wyndham St. Louis Airport

St. Ann

CNY772

CNY909 total

includes taxes & fees

Aug 24 - Aug 25

20. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

CNY1,032

CNY1,207 total

includes taxes & fees

Aug 18 - Aug 19

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Go beyond your typical stay in South Roxana

Apartment

Pet friendly

Family friendly

Hot tub

Pool

Top landmarks in South Roxana

Dads Club Park

If you like spending time outside, why not spend the afternoon at Dads Club Park, a park in the heart of South Roxana. Want to stretch your legs some more? Head to The Gardens at SIUE and Lewis and Clark State Memorial Park, both nearby.

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South Roxana Dad's Club Park

South Roxana Dad's Club Park is worth a visit when in central South Roxana.

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South Roxana City Hall

South Roxana City Hall is worth a visit when in central South Roxana.

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Check out reviews of South Roxana hotels guests love

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Staff were all great"

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"Very nice. Staff was friendly"

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Great stay overall. No complaints."

Live by Loews - St.Louis

10/10 Excellent

"Fantastic stay!"

Home2 Suites by Hilton St. Louis Downtown

10/10 Excellent

"It was a great location for us."

Marriott St. Louis Grand

8/10 Good

"The hotel was clean. The staff was pleasant. There isn’t much to do around the hotel. The area is a bit rundown."

Hilton St. Louis at the Ballpark

10/10 Excellent

"Staff is amazing, incredibly nice and welcoming. Leah in the bar is a great bartender, kept everything moving even though it was incredibly busy. Only issue is the hotel has a slight musty smell. Excellent location for games. Would stay again."

The Royal Sonesta Chase Park Plaza St. Louis

8/10 Good

"This is a classic hotel in St. Louis, we had a nice stay and good service, I would say it could use a little updating, especially in the bathrooms."

Frequently asked questions

How much does a hotel room cost in South Roxana?

You can find top hotels in South Roxana from CNY413 with options to suit your budget and needs. To find an affordable hotel in South Roxana that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at South Roxana hotels?

Discover great deals on South Roxana hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on South Roxana hotels.

Can I book South Roxana hotels with free cancellation?

It's easy to book a refundable South Roxana hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central South Roxana?

For hotels in central South Roxana, check out TownePlace Suites by Marriott St. Louis Edwardsville, IL and Bel Air Motel. Travelers love TownePlace Suites by Marriott St. Louis Edwardsville, IL for its location, as well as the indoor pool, free buffet breakfast and 24-hour gym this hotel offers. Bel Air Motel is another popular central motel with free parking, plus free WiFi in the guestrooms.

Can I book refundable accommodations in South Roxana?

If you're looking for the flexibility to change your plans to South Roxana, most accommodations provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in South Roxana be like during my vacation?

July and August are typically the warmest months in South Roxana when the average temp is 75°F. January and February are the coldest months when the average temperature is 37°F. May and April are the months with the most rain.

Why should I book my South Roxana accommodation with Hotels.com?

There are lots of reasons to book your South Roxana trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Hotels in South Roxana

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in South Roxana?

1. Holiday Inn Express & Suites Edwardsville by IHG

2. Comfort Inn Edwardsville - St. Louis

3. Country Hearth Inn & Suites Edwardsville St. Louis

4. Red Lion Inn & Suites Pontoon Beach

5. The Great Rivers, an Ascend Collection Hotel

6. Hampton Inn & Suites St. Louis/Alton

7. Best Western Plus Parkway Hotel

8. Drury Inn & Suites St. Louis Collinsville

9. Best Western Troy Hotel

10. Comfort Inn Collinsville near St. Louis

11. Holiday Inn Express Troy by IHG

12. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

13. Super 8 by Wyndham Troy IL/St. Louis Area

14. Pear Tree Inn St. Louis Airport

15. Hyatt Select St. Louis Airport

16. Hampton Inn & Suites St. Louis at Forest Park

17. Red Roof Inn St Louis - Troy, IL

18. Drury Inn & Suites St. Louis Airport

19. Wingate by Wyndham St. Louis Airport

20. Drury Plaza Hotel St. Louis at the Arch

Go beyond your typical stay in South Roxana

Top landmarks in South Roxana

Dads Club Park

South Roxana Dad's Club Park

South Roxana City Hall

Check out reviews of South Roxana hotels guests love

Pear Tree Inn St. Louis Airport

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Clayton Plaza Hotel & Extended Stay

Live by Loews - St.Louis

Home2 Suites by Hilton St. Louis Downtown

Marriott St. Louis Grand

Hilton St. Louis at the Ballpark

The Royal Sonesta Chase Park Plaza St. Louis

Frequently asked questions

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