Hotels in Santa Isabel Cholula

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Where to stay in Santa Isabel Cholula?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santa Isabel Cholula on Hotels.com. These Santa Isabel Cholula hotels consistently deliver on quality, location and traveler experience. Last updated on October 21, 2026.

A large, historic building with a dome and multiple towers, surrounded by well-maintained gardens and palm trees.

A modern hotel room with a stone wall, a large bed, a sofa, a small table, and a balcony with outdoor seating.

A bedroom with a stone wall, wooden beams, a bed with pillows, a chandelier, and a window with curtains.

A bedroom with a large bed, a wooden ceiling, a stone wall, and a view of the outdoors.

1. Hacienda Santo Cristo Hotel & Spa - Adults Only

Atlixco

CNY581

CNY691 total

includes taxes & fees

Nov 17 - Nov 18

A dining area with wooden tables and chairs, a rustic stone wall, and decorative plants.

A hotel kitchen with a chef preparing food, various dishes on the counter, and branded coffee mugs.

A swimming pool with thatched-roof structures, surrounded by greenery.

A dining table set with wine glasses, cutlery, and decorative foliage.

2. BV Hotel Atlixco

Atlixco

CNY548

CNY652 total

includes taxes & fees

Oct 22 - Oct 23

An outdoor seating area with tables and chairs, large windows, and potted plants.

A modern bar area with a counter, bar stools, and shelves stocked with bottles.

A reception area with a wooden reception desk, a large blue and white vase, and a sign that reads "bienvenido a Hampton welcome".

A modern hotel lobby with a sofa, armchairs, a coffee table, and a potted plant.

3. Hampton Inn & Suites by Hilton Puebla

Tlaxcalancingo

CNY414

CNY493 total

includes taxes & fees

Oct 25 - Oct 26

A swimming pool with a tiled floor, lounge chairs, and umbrellas.

A modern hotel with a curved facade, multiple balconies, and a rooftop terrace.

A rooftop terrace with a modern outdoor seating area, including a sofa and a glass coffee table.

A modern reception area with a curved white reception desk, a black leather sofa, and a large window with a view of palm trees.

4. Sonata Hotel

Lomas de Angelópolis

CNY418

CNY498 total

includes taxes & fees

Oct 25 - Oct 26

A courtyard with a central lawn, surrounded by buildings with a modern architectural style, featuring large windows and a prominent tree in the background.

A modern building with a covered walkway, large windows, and a well-maintained garden.

A swimming pool surrounded by a stone wall with plants.

A corridor with a stone wall on one side and a blue wall on the other, with a tiled floor and recessed lighting.

5. Soleil Inn Atlixco

Atlixco

CNY405

CNY482 total

includes taxes & fees

Oct 22 - Oct 23

An indoor atrium with a central staircase, potted plants, and a hanging light fixture.

A modern hotel room with a wooden desk, a flat-screen TV, a blue chair, a sofa, and a decorative wall panel.

A multi-level atrium with terracotta planters, arched ceilings, and hanging lights.

A modern hotel room with a large bed, two bedside tables, a nightstand, a chair, and a decorative rug.

6. Hotel Casa de la Audiencia

Atlixco

CNY784

CNY933 total

includes taxes & fees

Nov 3 - Nov 4

An indoor swimming pool with lounge chairs, large windows, and a view of the city at night.

A multi-story hotel with a prominent Fiesta Inn sign, a parking lot, and a view of the surrounding area.

A modern reception area with a white desk, multiple shelves with decorative items, and a patterned wall.

A person sitting on a bed with a plate of food and a glass of orange juice.

7. Fiesta Inn Express Puebla Explanada

Cholula

CNY535

CNY636 total

includes taxes & fees

Oct 25 - Oct 26

A two-story building with a swimming pool, outdoor seating, and a well-maintained lawn.

A bathroom with a white vanity, a mirror, and a shelf with toiletries.

A modern living room with a grey sofa, two armchairs, a coffee table, and a TV mounted on the wall.

A dining area with tables set for breakfast, wicker chairs, and large windows offering a view of the outside.

8. Villas Grand Gardenia

Atlixco

CNY384

CNY456 total

includes taxes & fees

Oct 22 - Oct 23

A modern lobby with a reception desk, two seating areas, and a large abstract painting on the wall.

A modern hotel room with a large bed, a flat-screen TV, and a view of the city at night.

A modern lobby with a reception desk, seating area, and a decorative wall.

A multi-story building with a sign for 'Yoga Shala Casa Utpal'.

9. Kharma Suites

San Andrés Cholula

CNY297

CNY353 total

includes taxes & fees

Oct 25 - Oct 26

A rooftop pool with glass railings, a view of a cityscape, and a mountain in the background.

A gym with treadmills, ellipticals, and dumbbells, with a city view through large windows.

A modern dining area with tables and chairs, a buffet counter with food and drinks, and a city view through large windows.

A modern lobby with a city view, featuring a yellow sofa, grey sofas, and green armchairs.

10. Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

Angelópolis

CNY408

CNY485 total

includes taxes & fees

Oct 27 - Oct 28

A modern interior with yellow chairs, a hanging chair, and large windows.

A modern restaurant interior with wooden paneling, colorful seating, and a large window with a view.

A hotel sign with the name 'tru by Hilton' and a colorful mural depicting a building with a cross on top.

11. Tru By Hilton Puebla Angelopolis

Angelópolis

CNY354

CNY422 total

includes taxes & fees

Oct 28 - Oct 29

A modern interior with a seating area, a white chair, and a wall with a geometric pattern and text.

A modern hotel lobby with a dining area, seating by the window, and a visible office space in the background.

A modern interior with a large map and directional signs.

A modern office space with a meeting room, desks, chairs, and computers.

12. One Puebla Angelópolis Periférico

Tlaxcalancingo

CNY367

CNY437 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a central spiral staircase, large windows, and a polished floor.

A spacious restaurant with multiple dining areas, a central chandelier, and large windows.

A modern interior with a curved staircase, glass railings, and two computer monitors on a wooden table.

A modern lobby with a central seating area, large windows, and a television screen.

13. Hilton Garden Inn Puebla Angelópolis, Mexico

Angelópolis

CNY477

CNY568 total

includes taxes & fees

Nov 8 - Nov 9

A hotel with multiple balconies, a swimming pool, and outdoor seating areas.

A spacious lobby with a modern design, featuring a seating area with sofas and tables, a staircase, and a reception desk.

A pool area with palm trees, a statue, and a modern building with multiple floors and balconies.

A bar area with wooden tables and chairs, a wine rack, and a bar counter with bottles.

14. Camino Real Puebla Angelopolis

Angelópolis

CNY454

CNY540 total

includes taxes & fees

Nov 4 - Nov 5

A modern hotel room with a large dining table, comfortable seating, a flat-screen TV, and a city view through large windows.

A sauna with wooden benches, a central shower area, and a wall-mounted control panel.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with large windows.

A modern lounge area with seating, a bar, and a view of the cityscape.

15. Grand Fiesta Americana Puebla Angelópolis

Angelópolis

CNY1,000

CNY1,190 total

includes taxes & fees

Oct 30 - Oct 31

A hot tub with a wooden deck, surrounded by a pool, and a grassy area with a building in the background.

A modern outdoor pool area with a tiled deck, a covered seating area, and a view of the surrounding landscape.

A hotel room with a bed, a bedside table with a cup, a spoon, and a book. There is a TV mounted on the wall and a microwave in the kitchen area.

A hotel reception area with a wooden reception desk, a digital screen, and seating arrangements.

16. Hit Hoteles Aeropuerto Puebla

Huejotzingo

CNY489

CNY582 total

includes taxes & fees

Oct 23 - Oct 24

A modern hotel with a glass facade, multiple floors, and a prominent signage for 'Encore'.

A modern indoor pool with clear glass walls, a metal ladder, and a view of a cityscape at night.

A modern interior with a glass staircase, a reception desk, and a unique ceiling light fixture.

A modern indoor recreational area with pool tables, foosball, and bar seating.

17. Ramada Encore by Wyndham Puebla

Coronango

CNY444

CNY528 total

includes taxes & fees

Nov 2 - Nov 3

A modern lounge area with a city view, a bar with high stools, and plush seating.

A restaurant with a city view, modern decor, and a mix of seating arrangements.

A modern hotel room with a large bed, a desk, a TV, and a seating area.

A balcony with a glass railing, a round table with chairs, and a bowl of fruit.

18. Radisson Puebla Angelopolis

Angelópolis

CNY394

CNY469 total

includes taxes & fees

Nov 2 - Nov 3

A modern lounge area with seating, a coffee bar, and a brick wall.

A modern bar area with a brick wall, wooden furniture, and a variety of bottles on shelves.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a brick building with large windows.

A modern lobby with seating areas, a reception desk, and a bookshelf.

19. Four Points By Sheraton Puebla

Puebla

CNY411

CNY489 total

includes taxes & fees

Oct 29 - Oct 30

A modern gym with multiple treadmills, stationary bikes, and weight machines.

A Holiday Inn Express hotel with a modern design, featuring a prominent curved corner and illuminated signage.

A modern indoor pool area with a long pool, seating area with chairs, and a glass wall with a green wall behind it.

A long dining table set for a formal event with white chairs, a cityscape view in the background, and a crane visible in the distance.

20. Holiday Inn Express Puebla by IHG

Puebla

CNY388

CNY461 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Go beyond your typical stay in Santa Isabel Cholula

Pet friendly

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Family friendly

Spa

Hot tub

Check out reviews of Santa Isabel Cholula hotels guests love

Hotel Isabel

10/10 Excellent

"Clean Room , Kind Staff and Dellicious Breakfast"

Holiday Inn Express Puebla by IHG

8/10 Good

"We arrived on a late night and the assigned room wasn’t properly cleaned specifically the bathroom shower and sink, we notified the supervisor next day and she assigned a great housekeeper named Nadia who took care of our cleaning, she was very thoroughly and promptly fixed the problem we were so grateful with her services she was really professional and proud of her work, even though she was assigned to a different area she was always greeting us and asking if everything was going well with our room."

Quinta Real Puebla

10/10 Excellent

"This is an excellent property featuring impeccable rooms and amenities. Throughout our stay, the staff was remarkably helpful and welcoming. Additionally, the location is ideal, situated just a few blocks from the cathedral and the Zócalo."

Holiday Inn Puebla La Noria by IHG

8/10 Good

"Muy bueno el hotel, el staff muy amable. Lo único que la limpieza deja mucho que desear y faltan algunas amenidades como gorra de baño. Por lo demás muy bien."

NH Puebla Centro Histórico

10/10 Excellent

"Me gusta mucho"

voco Royalty Puebla Downtown by IHG

10/10 Excellent

"Very nice place and close to the plaza and enjoy the stay"

Hotel Boutique Casareyna

10/10 Excellent

"Excelente comida en el restaurante"

Four Points By Sheraton Puebla

8/10 Good

"Todo muy bien en general pero lo que más me gustó fue que tienen empatía con las mascotas tienen una perrita que adoptaron de la calle es muy linda y tranquila ella siempre está a la entrada del hotel tiene su camita la cuidan y le dan de comer le dicen guardiana muy bien por eso y cuando vuelva a Puebla de seguro llegaré a hospedarme de nuevo ahí por el buen servicio y por supuesto para saludar a Guyana. Muchas felicidades. Gracias"

Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG

10/10 Excellent

"Clean rooms and the location was convenient"

Frequently asked questions

How much does a hotel room cost in Santa Isabel Cholula?

You can discover great hotels in Santa Isabel Cholula from CNY353 with properties to suit all budgets and needs. To find an affordable hotel in Santa Isabel Cholula that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at Santa Isabel Cholula hotels?

Discover great deals on Santa Isabel Cholula hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Isabel Cholula hotels.

Can I book Santa Isabel Cholula hotels with free cancellation?

It's easy to book a refundable Santa Isabel Cholula hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some top pet-friendly hotels in Santa Isabel Cholula?

Consider one of our travelers' favorite pet-friendly hotels in Santa Isabel Cholula:

Hotel Hacienda Del Río: A hotel with a guest rating of 10 out of 10

You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Santa Isabel Cholula.

What are some of the best hotels in Santa Isabel Cholula for couples?

Choose a top-rated Santa Isabel Cholula romantic hotel and enjoy your couple's getaway. Our travelers love Hotel Hacienda Del Río, a hotel with a restaurant and 3 outdoor pools. Discover more hotels in Santa Isabel Cholula on Hotels.com for couples by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".

What are the top Santa Isabel Cholula hotels with a pool?

For some added luxury, discover the best Santa Isabel Cholula hotels with a pool. Hotel Hacienda Del Río is a great hotel with 3 outdoor pools and an indoor pool, and a guest rating of 10 out of 10. Plus, you can make the most of its restaurant and bar/lounge. To find more stays in Santa Isabel Cholula with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".

What are some of the best Santa Isabel Cholula hotels with free parking?

If you're driving, a great Santa Isabel Cholula hotel with free parking is a bonus. Our travelers' favorites include:

Hotel Hacienda Del Río: A hotel with an average guest rating of 10 out of 10

What are some popular hotels in central Santa Isabel Cholula?

If you're looking for hotels in central Santa Isabel Cholula, check out Hotel Hacienda Del Río and Hotel Casa de la Audiencia. Travelers love Hotel Hacienda Del Río for its location, as well as the 3 outdoor pools, restaurant and bar/lounge this hotel offers. Hotel Casa de la Audiencia is another popular central hotel with spa services, a rooftop terrace and proposal/romance packages. Los Angeles and Tlaxcalancingo are some of the most central neighborhoods for your Santa Isabel Cholula vacation.

What hotels do travelers recommend in Santa Isabel Cholula?

Guests like Camino Real Puebla Angelopolis, Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG and Tru By Hilton Puebla Angelopolis.

Can I book a refundable accommodation in Santa Isabel Cholula?

If you're looking for the flexibility to change your plans to Santa Isabel Cholula, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Santa Isabel Cholula be like during my vacation?

The warmest months in Santa Isabel Cholula are usually April and March with an average temp of 66°F. January and December are the chilliest months when the average temp is 61°F. The rainiest months are September and June.

Why should I book my Santa Isabel Cholula accommodation with Hotels.com?

There are plenty of reasons to book your Santa Isabel Cholula travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

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