Hotels in Santa Isabel

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Where to stay in Santa Isabel?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santa Isabel on Hotels.com. These Santa Isabel hotels consistently deliver on quality, location and traveler experience. Last updated on September 24, 2026.

A tented accommodation with a bed, bedside tables, a lamp, a refrigerator, and a plant.

A wooden structure with a series of vertical beams and a horizontal beam with water dripping from it.

A wooden structure with a window, rainwater dripping from the roof, and a view of green foliage.

A tent-style room with a bed, a bench, a lamp, a basket, and a view of greenery outside.

1. Hacienda Doña Minga

Adjuntas

CNY1,678

CNY1,829 total

includes taxes & fees

Sep 26 - Sep 27

A spacious lobby with high ceilings, wooden furniture, and potted plants.

A wooden deck with a pergola, surrounded by tropical plants and rocks.

A bedroom with a wooden bed, a bedside table with a lamp, an air conditioner, and a wall-mounted shelf with decorative items.

A swimming pool with a view of a building in the background.

2. Hacienda Villa Sotomayor

Adjuntas

CNY428

CNY527 total

includes taxes & fees

Oct 12 - Oct 13

A compact bedroom with a bed, a small black appliance, a white air conditioning unit, and a wooden floor.

A staircase with a flag, a chandelier, and wall art.

A compact living space with a flat-screen TV, a compact kitchenette, a dining area with a round table and chairs, and a storage unit with shelves.

A building with a flag, a coffee shop, and a souvenir shop.

3. Casa Patriota

Lares

CNY302

CNY396 total

includes taxes & fees

Sep 27 - Sep 28

4. Casa Campo Bed and Breakfast

San Sebastian

CNY1,107

CNY1,185 total

includes taxes & fees

Sep 27 - Sep 28

A swimming pool with a stone border, a thatched-roof structure, and a view of green hills in the background.

A hotel entrance with a green wall, a carousel, and a reception area.

A brightly lit indoor dining area with tables and chairs, neon signs, and a vending machine.

A terrace with wicker furniture, a white railing, and a 'LOVE' sign.

5. Hotel Vista Verde

Yauco

CNY785

CNY889 total

includes taxes & fees

Oct 1 - Oct 2

A modern building with a bridge over a small pond, surrounded by lush greenery and palm trees.

A modern lobby with a large, glittery whale sculpture, a blue wave design, and a sign indicating a smoking area.

A water feature with a waterfall and a bird sculpture in a landscaped area.

A spacious lobby with large windows, blue seating, and a modern design.

6. Costa Bahia Hotel & Convention Center

Guayanilla

CNY767

CNY919 total

includes taxes & fees

Oct 18 - Oct 19

A swimming pool with lounge chairs and a table, surrounded by a building with multiple windows and a door leading inside.

A modern living room with a red sofa and matching cushions, two small potted plants, and a large window providing a view of the outside.

A modern building with multiple floors and large windows.

A bed with a patterned white bedspread and a wooden headboard.

7. Royal Delonix Hotel

Penuelas

CNY604

CNY734 total

includes taxes & fees

Oct 18 - Oct 19

A hammock on a wooden deck with a view of lush greenery and mountains.

A lush, green landscape with a cluster of buildings featuring green roofs, surrounded by dense forest.

A spacious room with wooden beams, large windows, and exercise mats.

A lush, green landscape with a series of buildings featuring green roofs, surrounded by dense vegetation and a winding road.

8. Casa Grande Mountain Retreat - Adults Only

Utuado

CNY891

CNY1,078 total

includes taxes & fees

Oct 6 - Oct 7

A cozy bar area with a sofa, stools, and a mural of a coastal town.

A single-bed room with a wooden headboard, a bedside table, and a small desk with a chair.

A covered outdoor seating area with tables and chairs, a swimming pool, and a white fence with palm trees in the background.

A garden area with various flowering plants and a concrete structure.

9. Arecibo Inn

Arecibo

CNY517

CNY563 total

includes taxes & fees

Sep 29 - Sep 30

A pool area with a blue pool, white railing, and a table with chairs.

A hallway with a mirrored console table, two framed floral paintings, and a chandelier.

A bar area with white chairs and a wooden counter, featuring a variety of bottles and a television screen.

A poolside area with a blue umbrella, a small gazebo, and a potted plant.

10. Parador El Buen Café

Hatillo

CNY832

CNY891 total

includes taxes & fees

Sep 28 - Sep 29

A balcony with a table and chairs, overlooking a coastal view with rocks and greenery.

A modern room with a glass table, white chairs, a sofa, and a TV mounted on the wall.

A building with a modern design, a white car parked in front, and a large rock formation.

A room with a large window offering a view of the sea, a ceiling fan, a dining table with chairs, and a sofa.

11. Vacation Rental Arecibo PR

Arecibo

CNY520

CNY567 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a bed, a TV, a desk, a chair, a lamp, a painting, and a view of the outside.

A hot tub with a waterfall feature, surrounded by wooden steps and a tiled edge.

A yellow building with a red-tiled roof, a signboard, and a staircase leading to the entrance.

A compact kitchen with a sink, dishwasher, and wooden cabinets.

12. Caño Tiburones Guest House

Arecibo

CNY698

CNY760 total

includes taxes & fees

Oct 6 - Oct 7

A set of outdoor brick steps leading up to a covered area with a concrete floor.

A building with a symmetrical facade, multiple columns, and a central entrance.

A reception area with a wooden reception desk, a brown sofa with patterned cushions, and a poster on the wall.

A lobby with a sofa, two armchairs, a coffee table, and a patterned curtain.

13. Hostal Universitario

San German

CNY470

CNY512 total

includes taxes & fees

Oct 2 - Oct 3

A pool area with a view of the ocean, surrounded by palm trees and a covered seating area.

A wooden staircase leading to a sandy beach with palm trees and a clear blue ocean.

A wooden gate leading to a beach with palm trees and ocean views.

A coastal resort with multiple buildings, a sandy beach, and palm trees.

14. Hotel El Guajataca

Quebradillas

CNY787

CNY858 total

includes taxes & fees

Sep 27 - Sep 28

A modern interior with a four-poster bed, a round coffee table, and a bookshelf.

A stone tower with a doorway leading to a covered entrance, surrounded by lush greenery and palm trees.

A covered outdoor seating area with a white sofa, a round table with a flower arrangement, and a wicker chair.

A bedroom with a four-poster bed, a sofa, and a large wooden wardrobe.

15. Royal Isabela

Isabela

CNY3,054

CNY3,994 total

includes taxes & fees

Oct 11 - Oct 12

A small outdoor pool area with a white table and chairs, a decorative sun wall, and a tiled floor.

A modern living space with a kitchen area, a dining table, and a sofa with cushions.

A well-lit outdoor area with a palm tree and decorative plants, a sign reading "MEXICO," and a pathway leading into the building.

A modern hotel room with a bed, a TV, a bathroom with a shower, and a small sink.

16. Hotel Nuevo Mejico

Ponce

CNY554

CNY604 total

includes taxes & fees

Oct 12 - Oct 13

A modern living room with a white dining table, a blue sofa, and a ceiling fan.

A bright, white-walled room with a tiled floor, a wooden chair, a small table, and a door leading to another space.

A bedroom with a bed, a nightstand, a chair, and a window with curtains.

A modern kitchen with white cabinets, a refrigerator, a microwave, an oven, and a dining table with chairs.

17. Arecibo Hotel 2101

Arecibo

CNY698

CNY1,456 total

includes taxes & fees

Sep 26 - Sep 27

A modern infinity pool with a clear view of the ocean and palm trees.

A lighthouse with a red roof, white walls, and a flagpole.

A balcony with a view of the ocean and palm trees, white chairs, and a tiled floor.

A modern room with a dining area, a potted plant, and a view through large windows.

18. Ventana al Atlantico at Arecibo 681 Ocean Drive

Arecibo

CNY732

CNY1,031 total

includes taxes & fees

Sep 30 - Oct 1

A covered balcony with tiled flooring, a hanging light fixture, and a potted plant.

A spacious room with a tiled floor, a large window with a view, a desk, and a chair.

A spacious living room with a large mirror, a wooden cabinet, and a chandelier.

A residential building with a gated entrance, a covered porch, and a large window.

19. Hatillo

Arecibo

CNY19,026

CNY22,926 total

includes taxes & fees

Sep 26 - Sep 27

A beach with clear water, a sandy shore, and a rocky outcrop in the distance.

A modern two-story house with a covered patio, a front lawn, and a palm tree.

A modern two-story house with a flat roof, a covered patio, and a well-maintained lawn.

A hotel room with a bed, a mirror, and a door.

20. Casa vacacional en Arenales Isabela

Isabela

CNY538

CNY1,390 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Go beyond your typical stay in Santa Isabel

Pet friendly

Pool

Check out reviews of Santa Isabel hotels guests love

Hotel El Guajataca

8/10 Good

"El staff tanto del restaurante como del counter son excelente, lo que hace falta es la limpieza, tienen que mejor y hacer una mejor decoracion, ya les toca hacer una buena pintura, cambiar sabanas y toallas la vista y el lugar es expectacular, la comida de la actividad de veras deliciosa. I la farina en el desayuno demasiado rica. Gracias a todos por tan exclente servicio al cliente lo que deben mejorar es la limpieza un poco de pintura y decoracion y ese parador seria expectacular no puede tener mejor ubicacion cerca de jobos y de muchos lugares bellos. Por el costo es bueno no esta mal."

Royal Isabela

10/10 Excellent

"Amazing views from our room pictures online don’t do it justice."

Costa Bahia Hotel & Convention Center

10/10 Excellent

"Un lugar seguro y divertido para todas las edades."

Vacation Rental Arecibo PR

8/10 Good

"Location and view."

Hotel Nuevo Mejico

10/10 Excellent

"Todo muy lindo y cómodo"

Casa Patriota

10/10 Excellent

"Viaje por motivo de trabajo y fue justo lo q requerí."

Arecibo Inn

10/10 Excellent

"La habitacion espectacular"

3-Bedroom House in Quebradillas

10/10 Excellent

"Great home, family friendly ! Convenient location to the main highway. Great restaurants around it."

Frequently asked questions

How much does a hotel room cost in Santa Isabel?

You can discover great hotels in Santa Isabel from CNY396 with properties to suit all budgets and needs. If you're after an affordable hotel in Santa Isabel that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Santa Isabel hotels?

Discover great deals on Santa Isabel hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Santa Isabel hotels.

Can I book Santa Isabel hotels with free cancellation?

To book a refundable Santa Isabel hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What accommodations do travelers like in Santa Isabel?

Guests like Hacienda Villa Sotomayor, Casa Patriota and Hacienda Doña Minga.

Can I book a refundable hotel in Santa Isabel?

If you need the flexibility to change your travel plans to Santa Isabel, most accommodations offer refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Santa Isabel be like during my vacation?

With an average temperature of 76°F during the coldest months, Santa Isabel is a great place to visit any time of year.

Why should I book my Santa Isabel accommodation with Hotels.com?

There are plenty of reasons to book your Santa Isabel travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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