Hotels in La Mesa

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Where to stay in La Mesa?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in La Mesa

Learn more about La Mesa

The region around La Mesa is home to attractions such as Las Penas Ecological Park and Volcan Nevado de Colima National Park.

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Frequently asked questions

What hotels do travelers like in La Mesa?
Can I book refundable hotels in La Mesa?
If you need the flexibility to change your travel plans to La Mesa, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in La Mesa be like during my vacation?
The warmest months in La Mesa are usually May and April with an average temp of 70°F. January and February are the chilliest months when the average temp is 63°F. The rainiest months are August and July.
Why should I book my La Mesa hotel through Hotels.com?
There are plenty of reasons to book your La Mesa travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.