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Hotels in La Mesa

October 2026
8
November 2026

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This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Where to stay in La Mesa?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in La Mesa on Hotels.com. These La Mesa hotels consistently deliver on quality, location and traveler experience. Last updated on October 9, 2026.
A modern kitchen with a large TV, bar stools, and a scenic view.
A modern living room with a leather sofa, a bookshelf, and a staircase leading to an outdoor area.
A modern hotel with a distinctive wooden facade and a blue and white color scheme.
A modern outdoor dining area with tables and chairs, large windows offering a view of hills, and various outdoor kitchen appliances.

1. Tryp By Wyndham Ciudad Guzman Uttsa

Tryp By Wyndham Ciudad Guzman Uttsa
Zapotlán el Grande
CNY557
CNY674 total
includes taxes & fees
Nov 1 - Nov 2
Tryp By Wyndham Ciudad Guzman Uttsa
A courtyard with a swimming pool, surrounded by plants and stone walls.
A multi-level atrium with a glass ceiling, balconies with hanging planters, and a central planter with various plants.
A courtyard with stone arches, potted plants, and a tiled floor.
A spacious lobby with a central seating area, multiple balconies with hanging plants, and a tiled floor.

2. Hotel Zapotlan

Hotel Zapotlan
Zapotlán el Grande
CNY237
CNY287 total
includes taxes & fees
Oct 15 - Oct 16
Hotel Zapotlan
Interior
A restaurant interior with a projection screen displaying a river scene, wooden bookshelves, and a seating area with tables and chairs.
Living area
A bedroom with a large bed, a nightstand, a chair, and a balcony with a view of the city.

3. Hotel Uttsa Inn Tamazula

Hotel Uttsa Inn Tamazula
Tamazula de Gordiano
CNY336
CNY406 total
includes taxes & fees
Oct 9 - Oct 10
Hotel Uttsa Inn Tamazula
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and greenery.
An indoor courtyard with arches, potted plants, and a tiled floor.
A corridor with tiled flooring, potted plants, and a wooden ceiling.
A spa area with a pool, towels, and decorative wall elements.

4. La Casa de los Patios Hotel & Spa

La Casa de los Patios Hotel & Spa
Sayula
CNY462
CNY559 total
includes taxes & fees
Oct 12 - Oct 13
La Casa de los Patios Hotel & Spa
A swimming pool surrounded by yellow buildings with balconies, a clear sky, and a staircase leading to an upper level.
A reception area with a white reception desk, a framed picture above the desk, and potted plants on either side.
A building with a sign reading "Capital O Colon".
A lobby with wicker furniture, a glass-top coffee table, and a large mirror.

5. Capital O Colón, Ciudad Guzmán Jalisco

Capital O Colón, Ciudad Guzmán Jalisco
Zapotlán el Grande
CNY149
CNY190 total
includes taxes & fees
Nov 4 - Nov 5
Capital O Colón, Ciudad Guzmán Jalisco
Interior
A patio with outdoor furniture, a wall-mounted decorative mirror, and a variety of plants.
A bed with a white bedspread, a dark brown skirt, and a heart-shaped decoration made of rose petals.
A lamp with a white shade and a gold base, a decorative figure, and a patterned armchair.

6. Hotel Boutique Casa Real

Hotel Boutique Casa Real
Zapotiltic
CNY326
CNY395 total
includes taxes & fees
Oct 9 - Oct 10
Hotel Boutique Casa Real
A courtyard with a swimming pool, multiple balconies, and a dining area with tables and chairs.
A room with a high ceiling, wooden beams, a chandelier, and a large window.
A courtyard with a fountain, potted plants, and a red building with arches.
An elegantly set dining table with glassware, floral centerpieces, and a framed painting on the wall.

7. Gran Casa Sayula Hotel & Spa

Gran Casa Sayula Hotel & Spa
Sayula
CNY665
CNY804 total
includes taxes & fees
Oct 12 - Oct 13
Gran Casa Sayula Hotel & Spa
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Go beyond your typical stay in La Mesa

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Hot tub
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Family friendly
Family friendly

Check out reviews of La Mesa hotels guests love

A modern kitchen with a large TV, bar stools, and a scenic view.
A modern living room with a leather sofa, a bookshelf, and a staircase leading to an outdoor area.
A modern hotel with a distinctive wooden facade and a blue and white color scheme.
A modern outdoor dining area with tables and chairs, large windows offering a view of hills, and various outdoor kitchen appliances.

Tryp By Wyndham Ciudad Guzman Uttsa

Tryp By Wyndham Ciudad Guzman Uttsa
Zapotlán el Grande

10/10 Exceptional

United States
Felix
Tryp By Wyndham Ciudad Guzman Uttsa
Interior
A restaurant interior with a projection screen displaying a river scene, wooden bookshelves, and a seating area with tables and chairs.
Living area
A bedroom with a large bed, a nightstand, a chair, and a balcony with a view of the city.

Hotel Uttsa Inn Tamazula

Hotel Uttsa Inn Tamazula
Tamazula de Gordiano

10/10 Exceptional

United States
Jorge
Hotel Uttsa Inn Tamazula
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and greenery.
An indoor courtyard with arches, potted plants, and a tiled floor.
A corridor with tiled flooring, potted plants, and a wooden ceiling.
A spa area with a pool, towels, and decorative wall elements.

La Casa de los Patios Hotel & Spa

La Casa de los Patios Hotel & Spa
Sayula

10/10 Exceptional

United States
juan
La Casa de los Patios Hotel & Spa
A courtyard with a swimming pool, multiple balconies, and a dining area with tables and chairs.
A room with a high ceiling, wooden beams, a chandelier, and a large window.
A courtyard with a fountain, potted plants, and a red building with arches.
An elegantly set dining table with glassware, floral centerpieces, and a framed painting on the wall.

Gran Casa Sayula Hotel & Spa

Gran Casa Sayula Hotel & Spa
Sayula

10/10 Exceptional

United States
jose
Gran Casa Sayula Hotel & Spa
A courtyard with a swimming pool, surrounded by plants and stone walls.
A multi-level atrium with a glass ceiling, balconies with hanging planters, and a central planter with various plants.
A courtyard with stone arches, potted plants, and a tiled floor.
A spacious lobby with a central seating area, multiple balconies with hanging plants, and a tiled floor.

Hotel Zapotlan

Hotel Zapotlan
Zapotlán el Grande

10/10 Exceptional

United States
Ana Itzel
Hotel Zapotlan
A swimming pool surrounded by yellow buildings with balconies, a clear sky, and a staircase leading to an upper level.
A reception area with a white reception desk, a framed picture above the desk, and potted plants on either side.
A building with a sign reading "Capital O Colon".
A lobby with wicker furniture, a glass-top coffee table, and a large mirror.

Capital O Colón, Ciudad Guzmán Jalisco

Capital O Colón, Ciudad Guzmán Jalisco
Zapotlán el Grande

10/10 Exceptional

United States
José Petronilo
Capital O Colón, Ciudad Guzmán Jalisco

Frequently Asked Questions

How much does a hotel room cost in La Mesa?

You can find top hotels in La Mesa from CNY148 with options to suit your budget and needs. If you're after an affordable hotel in La Mesa that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at La Mesa hotels?

Discover great deals on La Mesa hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on La Mesa hotels.

Can I book La Mesa hotels with free cancellation?

To book a refundable La Mesa hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some top pet-friendly hotels in La Mesa?

Consider one of our travelers' favorite pet-friendly hotels in La Mesa:

You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in La Mesa.

What are some of the best La Mesa hotels with free parking?

If you're arriving by car, choosing a great La Mesa hotel with free parking is a plus. Our travelers' favorites include:

What are some popular hotels in central La Mesa?

If you're looking for hotels in central La Mesa, check out Tryp By Wyndham Ciudad Guzman Uttsa and Chalet de Colombo Hotel. Travelers love Tryp By Wyndham Ciudad Guzman Uttsa for its location, as well as the restaurant, free on-the-go breakfast and Netflix this hotel offers. Chalet de Colombo Hotel is another popular central ranch with a terrace and free parking, plus free WiFi in the guestrooms.

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