Hotels in Santa Cruz

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Check prices for these dates

Tonight
Dec 24 - Dec 25
Tomorrow
Dec 25 - Dec 26
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Where to stay in Santa Cruz?

Rooftop terrace
Tequendama Hotel Medellín
Tequendama Hotel Medellín
4.0 star property
8.0 out of 10, Very Good, (428)
The price is CNY524
CNY524 total
Jan 16 - Jan 17, 2026
Tequendama Hotel Medellín
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Santa Cruz and vicinity

Front of property
Hotel Provenza Garden

Hotel Provenza Garden

Hotel Provenza Garden
3.0 star property
El Poblado
8.4 out of 10, Very Good, (172)
The price is CNY356
CNY356 total
Jan 12 - Jan 13, 2026
Hotel Provenza Garden
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out reviews of Santa Cruz hotels guests love

Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

10/10 Excellent
"Solid choice in Poblado. "
ryan s. 4-night trip
Posted 11 hours ago
Dann Carlton Medellin Hotel

Frequently asked questions

How much does a hotel room cost in Santa Cruz?
You can discover great hotels in Santa Cruz from CNY338 with properties to suit all budgets and needs. If you're after an affordable hotel in Santa Cruz that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Santa Cruz hotels?
Discover great deals on Santa Cruz hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Santa Cruz hotels.
Can I book Santa Cruz hotels with free cancellation?
To book a refundable Santa Cruz hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some popular hotels in central Santa Cruz?
For hotels in central Santa Cruz, check out Versus Hotel and Selvario 36 Hotel. Travelers love Versus Hotel for its location, as well as the indoor pool, free parking and concierge services this hotel offers. Selvario 36 Hotel is another popular central hotel with a restaurant, a bar/lounge and spa services. Stay at one of these hotels for easy access to top sights like Poblado Park, Lleras Park, and Atanasio Giradot Stadium. El Poblado and Laureles are some of the most central neighborhoods for your Santa Cruz vacation.
What hotels do travelers like in Santa Cruz?
Guests like Heiss Hotel By Jalo, Calle Flora Hotel by Jalo and Hotel Dorado La 70.
Can I book refundable accommodations in Santa Cruz?
If you need the flexibility to change your plans to Santa Cruz, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Santa Cruz be like during my trip?
The warmest months in Santa Cruz are usually August and July with an average temp of 66°F. December and January are the chilliest months when the average temp is 64°F. The rainiest months are May and April.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are plenty of reasons to book your Santa Cruz travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.