Hotels in Isola

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Top 5 hotels in Isola at a glance

casa grimaldi — Located in Matelica. Guest rating: 8.0/10 — Very Good.
Hotel Eldorado — Located in Apiro. Guest rating: 8.0/10 — Very Good.
RELAIS FLORA BERTA — Located in Matelica.
Relais Del Borgo Hotel e Spa — 4-star hotel in Staffolo. Guest rating: 8.8/10 — Excellent.
Hotel Terme di Frasassi — Located in Genga. Guest rating: 8.6/10 — Excellent.

Where to stay in Isola?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Isola on Hotels.com. These Isola hotels consistently deliver on comfort, location and traveler experience. Last updated on August 28, 2026.

casa grimaldi

Matelica

CNY929

CNY1,022 total

includes taxes & fees

Aug 29 - Aug 30

Standard Double or Twin Room | In-room safe, desk, soundproofing, WiFi (free)

Hotel Eldorado

Apiro

CNY496

CNY545 total

includes taxes & fees

Aug 31 - Sep 1

Luxury Suite, Park View | In-room safe, WiFi (free)

RELAIS FLORA BERTA

Matelica

CNY5,126

CNY5,638 total

includes taxes & fees

Sep 28 - Sep 29

Body treatments, body wraps, body scrubs, facials

Relais Del Borgo Hotel e Spa

Staffolo

CNY1,478

CNY1,626 total

includes taxes & fees

Sep 28 - Sep 29

Classic Triple Room, Mountain View | Down comforters, minibar, in-room safe, desk

Seasonal outdoor pool, open 10:00 AM to 7:00 PM, pool umbrellas

Hotel Terme di Frasassi

Genga

CNY789

CNY868 total

includes taxes & fees

Sep 27 - Sep 28

Superior Room, 1 King Bed, Terrace | WiFi (free)

Villa Miliani

Fabriano

CNY565

CNY653 total

includes taxes & fees

Aug 30 - Aug 31

Classic Room | Desk, iron/ironing board, WiFi (free), bed sheets

Tuttaterra

Serra San Quirico

CNY712

CNY783 total

includes taxes & fees

Sep 9 - Sep 10

Relais Villa Fornari

Camerino

CNY747

CNY822 total

includes taxes & fees

Sep 11 - Sep 12

Outdoor pool, pool umbrellas, sun loungers

Couples treatment rooms, Turkish bath, body treatments, sports massages

Hotel Le Grotte

Genga

CNY957

CNY1,053 total

includes taxes & fees

Sep 27 - Sep 28

Couples treatment rooms, sauna, steam room, hot stone massages

Palazzo Cortesi Butique Hotel

Macerata

CNY904

CNY1,002 total

includes taxes & fees

Sep 14 - Sep 15

Borgo Lanciano Resort & Spa

Castelraimondo

CNY951

CNY1,047 total

includes taxes & fees

Sep 27 - Sep 28

Junior Room | Minibar, in-room safe, laptop workspace, blackout drapes

Executive Suite | Living area | 40-inch flat-screen TV with satellite channels

Relais La Colombaia

Appignano

CNY609

CNY904 total

includes taxes & fees

Aug 31 - Sep 1

Seasonal outdoor pool, pool umbrellas, sun loungers

Junior Suite, Garden View (Catria) | Down comforters, pillowtop beds, in-room safe, desk

Down comforters, pillowtop beds, in-room safe, desk

Serre Alte Landscape luxury Rooms

Matelica

CNY1,730

CNY1,903 total

includes taxes & fees

Sep 28 - Sep 29

City Apartment, 2 Bedrooms | Living area | 32-inch flat-screen TV with digital channels, TV

Guest House Viaroma

San Severino Marche

CNY541

CNY595 total

includes taxes & fees

Sep 26 - Sep 27

Sauna, hot tub, Turkish bath, body treatments, body wraps, facials

Outdoor pool, open 9:30 AM to 8:00 PM, sun loungers

Hotel Federico II

Jesi

CNY743

CNY841 total

includes taxes & fees

Aug 31 - Sep 1

Couples treatment rooms, sauna, Turkish bath, body treatments

Interno Marche Design Experience Hotel

Tolentino

CNY1,214

CNY1,336 total

includes taxes & fees

Sep 26 - Sep 27

La Torre Hotel

Maiolati Spontini

CNY609

CNY670 total

includes taxes & fees

Sep 28 - Sep 29

2 outdoor pools, pool umbrellas, sun loungers

Exclusive Studio Suite, Jetted Tub, Garden View (Walter) | Premium bedding, desk, blackout drapes, WiFi (free)

Le MaRaClà Country House

Jesi

CNY761

CNY861 total

includes taxes & fees

Sep 17 - Sep 18

Hotel Villa Verdefiore

Appignano

CNY707

CNY777 total

includes taxes & fees

Sep 22 - Sep 23

Select Comfort beds, minibar, desk, soundproofing

Cluentum

Tolentino

CNY609

CNY669 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Go beyond your typical stay in Isola

Pet friendly

Pool

Spa

Family friendly

Hot tub

Check out reviews of Isola hotels guests love

Villa Miliani

10/10 Excellent

"Very clean, friendly staff"

Hotel Le Grotte

10/10 Excellent

"The hotel is wonderful and has the most amazing staff"

Best Western Hotel I Colli

8/10 Good

"Good room and staff are helpful"

Pineta Hotel

10/10 Excellent

"The hotel is located in a somewhat hidden but very quiet area. My family and I stayed there for 4 nights and I must say we had a great time. The building is new, and direct access to the room by car is a plus. Cleanliness is excellent, as is the courtesy and helpfulness of the staff. Breakfast was good. Highly recommended."

Villa Quiete

10/10 Excellent

"Exactly as advertised 👌"

Interno Marche Design Experience Hotel

10/10 Excellent

"The staff were incredible and the room fantastic. I cannot say enough about how helpful and friendly the entire team was during our stay."

B&B HOTEL Fabriano Janus

10/10 Excellent

"clean room and friendly staff"

Frequently asked questions

How much does a hotel room cost in Isola?

You can discover great hotels in Isola from CNY479 with properties to suit all budgets and needs. To find an affordable hotel in Isola that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at Isola hotels?

Discover great deals on Isola hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Isola hotels.

Can I book Isola hotels with free cancellation?

To book a refundable Isola hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Isola?

If you're looking for hotels in central Isola, check out Colle Sul Lago. Travelers love Colle Sul Lago for its location, as well as the seasonal outdoor pool, sauna and rooftop terrace this country house offers.

What accommodations do travelers recommend in Isola?

Guests like Hotel Terme di Frasassi.

Can I book a refundable accommodation in Isola?

If you're looking for the flexibility to change your plans to Isola, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Isola be like during my vacation?

The warmest months in Isola are usually August and July with an average temp of 74°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are May and November.

Why should I book my Isola hotel through Hotels.com?

There are plenty of reasons to book your Isola travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

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