Hotels in De Soto

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Where to stay in De Soto?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in De Soto on Hotels.com. These De Soto hotels consistently deliver on comfort, location and traveler experience. Last updated on August 27, 2026.

A modern kitchen with a central island, built-in appliances, and a view into the dining area.

A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.

A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.

A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

CNY692

CNY792 total

includes taxes & fees

Sep 27 - Sep 28

A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.

A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.

A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.

A spacious lobby with a modern design, featuring a large seating area with purple and gray chairs, a patterned carpet, and a cityscape mural on the wall.

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Festus

CNY680

CNY777 total

includes taxes & fees

Sep 10 - Sep 11

A gated entrance with a sign for Baymont by Wyndham, a parking area, and a building with arched windows.

A multi-story hotel with a brick facade and large windows, featuring a parking lot in front.

An indoor swimming pool with a tiled edge, surrounded by lounge chairs and a potted plant.

A building with a covered entrance, columns, and a view of the sky.

Baymont by Wyndham Festus

Festus

CNY448

CNY512 total

includes taxes & fees

Sep 20 - Sep 21

Super 8 by Wyndham Pevely

Pevely

CNY454

CNY521 total

includes taxes & fees

Sep 28 - Sep 29

A modern living room with a fireplace, leather sofas, a glass coffee table, and a large TV.

A multi-story building with a brick facade and large windows. There are several cars parked in front, and a small green bush is visible near the entrance.

A spacious dining area with multiple tables and chairs, a fireplace, and large windows allowing natural light.

A hotel room with two beds, a nightstand, a lamp, and a painting on the wall.

Days Inn & Suites By Wyndham Festus

Festus

CNY454

CNY519 total

includes taxes & fees

Sep 10 - Sep 11

A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

Hampton Inn & Suites By Hilton Festus

Festus

CNY601

CNY687 total

includes taxes & fees

Sep 3 - Sep 4

A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.

A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.

A hotel room with a shower, a bathtub, a toilet, a bed, a desk, a chair, and a television.

A hotel room with a living area, kitchenette, and a desk with a computer and chair.

Comfort Inn Festus - St Louis South

Festus

CNY407

CNY475 total

includes taxes & fees

Sep 20 - Sep 21

A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

An indoor swimming pool area with a hot tub, a table with chairs, and a sign warning of no lifeguard on duty.

A hotel room with a TV, a sofa, a small table, a lamp, and a carpeted floor.

A hotel room with a desk, two beds, a television, a lamp, and a cityscape painting on the wall.

Drury Inn & Suites St. Louis Arnold

Arnold

CNY847

CNY979 total

includes taxes & fees

Sep 13 - Sep 14

An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.

A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.

A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.

A spacious hotel lobby with a dining area, kitchen, and large windows.

Crown Pointe Lodge, BW Signature Collection

Farmington

CNY737

CNY802 total

includes taxes & fees

Sep 6 - Sep 7

A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.

A hotel room with a bed, a desk, a television, a sofa, and a lamp.

A modern building with a prominent entrance, large windows, and a covered parking area.

Pear Tree Inn St. Louis Arnold

Arnold

CNY605

CNY699 total

includes taxes & fees

Sep 8 - Sep 9

A stone building with a white porch and a small garden with yellow flowers.

A dining room with a long table set for a meal, surrounded by chairs with lace covers. A piano and a bookshelf are visible in the background.

A cozy seating area with wicker chairs and a coffee table, a brick wall, and a window with a view of greenery.

A vintage upright piano with a mirror above it, a lamp, and a floral wallpaper pattern.

Corner George Inn Bed & Breakfast

Maeystown

CNY864

CNY959 total

includes taxes & fees

Sep 9 - Sep 10

A Holiday Inn Express & Suites building with a covered entrance, brick facade, and multiple windows.

An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.

A lobby with a reception desk, two armchairs, a lamp, and a wall with wood grain artwork.

A hotel lobby with a central reception desk, multiple seating areas, and a tiled floor.

Holiday Inn Express & Suites Farmington by IHG

Farmington

CNY766

CNY834 total

includes taxes & fees

Sep 13 - Sep 14

A wooden deck with two Adirondack chairs and a hammock.

A spacious living room with wooden floors, a stone fireplace, and a mounted television.

A bedroom with a large bed, wooden ceiling, and a view of the outdoors.

A spacious living room with a wooden ceiling, a fireplace, and a television.

Tiny Houses of French Village

French Village

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A motel with a covered parking area, a brick facade, and a sign indicating it is number 8.

A laundry area with two washing machines and a dryer.

A breakfast area with a coffee machine, two coffee dispensers labeled 'Farm Brothers', and cereal boxes including 'Raisin Bran' and 'Frosted Flakes'.

Super 8 by Wyndham Potosi

Potosi

CNY391

CNY427 total

includes taxes & fees

Sep 3 - Sep 4

A large, two-story house with a wrap-around porch and a central tower.

A four-poster canopy bed with a wooden headboard, a chandelier, and a radiator on the floor.

A covered patio with a picnic table, surrounded by a brick pathway and greenery.

A dining room with a wooden table set for four, surrounded by upholstered chairs. A large wooden cabinet with intricate carvings is positioned against the wall.

The Conner House B&B

Prairie du Rocher

CNY1,050

CNY1,165 total

includes taxes & fees

Sep 28 - Sep 29

A cabin with a large window, surrounded by trees.

A cabin with a cozy interior, a dining area, and a visible window.

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

CNY623

CNY1,013 total

includes taxes & fees

Sep 1 - Sep 2

Vive mol

BONNE TERRE

CNY726

CNY1,059 total

includes taxes & fees

Sep 8 - Sep 9

Downtown Kimmswick Studio Renovated Prime Location

Imperial

A bedroom with a large window, a bed, a wooden chair, and a table.

A wooden cabin with large windows, a view of a lake, and a forested hillside.

A hotel room with two beds, a desk, and a view of the outdoors.

A wooden interior with a dining table and chairs, large windows with a view of a lake and trees, and a hanging pendant light.

YMCA Trout Lodge

Potosi

CNY1,024

CNY1,098 total

includes taxes & fees

Aug 30 - Aug 31

A spacious living area with a sectional sofa, a ceiling fan, and a view into the kitchen and dining area.

A wooden interior with a bed, a small table, and a wall-mounted rack.

A two-story wooden building with a balcony on the upper floor, a red door, and a concrete driveway.

A spacious room with a wooden dining table, benches, and chairs. There is a kitchen area with wooden cabinets and a small island. The room has a high ceiling with recessed lighting.

Spacious Franklin County Retreat on 80 Acres!

Luebbering

CNY3,065

CNY7,272 total

includes taxes & fees

Sep 10 - Sep 11

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Go beyond your typical stay in De Soto

Pet friendly

Pool

Family friendly

Top landmarks in De Soto

Sunrise Lake Beach

If being by the water is a major draw, Sunrise Lake Beach is a spot you might want to check out, located 6.4 mi (10.3 km) from central De Soto.

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Big Lake

Big Lake is 7 mi (11.3 km) from central De Soto, why not stop by during your stay.

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Valle Lake Beach

Valle Lake Beach is 6.4 mi (10.3 km) from central De Soto, why not stop by during your stay. Want to stretch your legs some more? Head to Sunrise Lake Park, located nearby.

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Sunrise Lake

Sunrise Lake is 6.4 mi (10.3 km) from central De Soto, why not stop by during your stay.

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Clear Lake

Clear Lake is 6.1 mi (9.8 km) from central De Soto, why not stop by during your stay.

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Ritcher Park

Ritcher Park is worth a visit when in central De Soto.

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Eastside Community Park

Eastside Community Park is worth a visit, located 0.7 mi (1.1 km) from central De Soto.

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Joachim Park

Joachim Park is worth a visit, located 0.4 mi (0.7 km) from central De Soto.

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Learn more about De Soto

De Soto is well-known for its attractions such as Sunrise Lake Beach and Washington State Park.

See all hotels in De Soto

A blue kayak on calm river water with trees and rocky cliffs in the background.

Check out reviews of De Soto hotels guests love

Super 8 by Wyndham Farmington

8/10 Good

"Best Super 8 stay I’ve had. Helpful and happy staff. Very clean rooms with daily service (something other hotels don’t seem to offer on long stays anymore). Close dining and shopping options. Close to state parks and other state attractions. Vending machine and a fair breakfast for food options. The pool, although I didn’t use, looked very well maintained. Blackout curtains and a pristine shower. My very minor complaints is plug in options. A lot of hotels nowadays have headlamps next to the bed with an outlet now. So to charge your phone the light needs to be left on…not great when you’re trying to sleep. Breakfast could also have more options than bread (bagels, biscuits, and toast), apples, and cereal. Besides that this was an excellent stay."

Comfort Inn Festus - St Louis South

8/10 Good

"Staff was very friendly and helpful. Room could have been a little cleaner. Standard free breakfast. Room needed some repairs."

Crown Pointe Lodge, BW Signature Collection

10/10 Excellent

"An awesome stay"

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

8/10 Good

"air wasnt working"

Drury Inn & Suites St. Louis Arnold

10/10 Excellent

"The property is very clean, looks newly remodeled. Two resturants you can walk to. Staff was so friendly. Stay here!"

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

10/10 Excellent

"Room was great. Breakfast was great. Staff was amazing."

Super 8 by Wyndham Bonne Terre

10/10 Excellent

"Amazing stay"

Holiday Inn Express & Suites Farmington by IHG

10/10 Excellent

"Clean and well maintained as you would expect from this chain."

WoodSpring Suites St. Louis Arnold

10/10 Excellent

"El staff fue muy exelente 🙏"

Frequently asked questions

How much does a hotel room cost in De Soto?

You can find top hotels in De Soto from CNY406 with options to suit your budget and needs. If you're after an affordable hotel in De Soto that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at De Soto hotels?

Discover great deals on De Soto hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on De Soto hotels.

Can I book De Soto hotels with free cancellation?

It's easy to book a refundable De Soto hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What accommodations do travelers recommend in De Soto?

Guests like Baymont by Wyndham Festus, Comfort Inn Festus - St Louis South and La Quinta Inn & Suites by Wyndham Festus - St. Louis South.

Can I book a refundable hotel in De Soto?

If you're looking for the flexibility to change your plans to De Soto, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in De Soto be like during my trip?

July and August are typically the warmest months in De Soto when the average temp is 75°F. January and February are the coldest months when the average temperature is 38°F. April and May are the months with the most rain.

Why should I book my De Soto hotel through Hotels.com?

There are lots of reasons to book your De Soto trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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