A conservatory with a glass dome, surrounded by a garden with pink flowers and benches.

Hotels in West Seneca

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Where to stay in West Seneca?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in West Seneca on Hotels.com. These West Seneca hotels consistently deliver on quality, location and traveler experience. Last updated on September 15, 2026.

A Country Inn & Suites hotel with a prominent entrance, multiple floors, and a well-lit facade.

A hotel lobby with a fireplace, seating areas, and a staircase.

An outdoor seating area with stone walls, a fireplace, and metal chairs.

A reception area with a wooden reception desk, framed pictures on the wall, and a welcome mat on the floor.

1. Country Inn & Suites by Radisson, Buffalo South I-90, NY

Buffalo

CNY915

CNY1,040 total

includes taxes & fees

Oct 14 - Oct 15

An indoor swimming pool with clear glass walls, a tiled floor, and a lifeguard chair.

A gym with exercise equipment, a mirror, and a television.

An outdoor patio with tables and chairs, umbrellas, and a building in the background.

A hotel room with a bed, a desk with a chair, a TV, a mirror, and a lamp.

2. Hampton Inn Buffalo South/I-90

Buffalo

CNY1,025

CNY1,166 total

includes taxes & fees

Oct 14 - Oct 15

An outdoor patio with wicker furniture and a large glass window.

A spacious indoor area with a dining area, seating, a fireplace, and a kitchen in the background.

A hotel room with a bed, a sofa, a small table, a TV, and a window with curtains.

A multi-story hotel with a central courtyard, large windows, and a well-lit entrance.

3. Staybridge Suites West Seneca by IHG

Buffalo

CNY1,617

CNY1,839 total

includes taxes & fees

Oct 13 - Oct 14

An outdoor patio with a fire pit, seating, and string lights.

An indoor swimming pool with tiled flooring, seating areas, and potted plants.

A modern indoor seating area with tables and chairs, a sofa with cushions, and hanging pendant lights.

A hotel with a prominent sign reading "HOME 2 HOME" and a covered parking area.

4. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Buffalo

CNY1,012

CNY1,151 total

includes taxes & fees

Sep 30 - Oct 1

A Holiday Inn Express building with a covered entrance, a flag, and a sign indicating the address.

A large indoor swimming pool with a curved edge, a lounge area with a sofa, and a door leading to another room.

A hotel lobby with a reception desk, seating area, and a long corridor.

A modern hotel lobby with a circular glass table surrounded by chairs, a bar area, and seating with orange cushions.

5. Holiday Inn Express Cheektowaga North East by IHG

Buffalo

CNY939

CNY1,096 total

includes taxes & fees

Sep 20 - Sep 21

A restaurant with multiple tables and chairs, a buffet area with bowls of fruits and snacks, and a view of the outside through large windows.

An indoor swimming pool with a tiled floor, surrounded by windows with a view of trees.

A hotel lobby with a reception desk, several chairs, a large mirror, and two vases with dried plants.

A hotel room with a bed, two armchairs, a nightstand with a lamp, and a painting on the wall.

6. Quality Inn Near Walden Galleria Mall

Buffalo

CNY658

CNY768 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with a bed, a desk with a television, a chair, and a window with curtains.

A reception area with a wooden reception desk, a cityscape painting, and a tiled floor.

A conference room with a large table surrounded by chairs, large windows with curtains, and a potted plant on the side.

A restaurant with multiple tables and chairs, a stone fireplace, and potted plants.

7. Best Western Galleria Inn & Suites

Buffalo

CNY557

CNY634 total

includes taxes & fees

Sep 20 - Sep 21

A Hampton Inn hotel with a modern facade, large windows, and a well-maintained parking lot.

A vending machine with snacks and drinks, including Coca-Cola, Sprite, and various chips.

An outdoor patio with a table and chairs, a blue sofa, and a large umbrella.

An indoor swimming pool with blue and yellow lounge chairs, large windows, and a tiled floor.

8. Hampton Inn Buffalo-Airport / Galleria Mall

Buffalo

CNY880

CNY1,001 total

includes taxes & fees

Oct 13 - Oct 14

A patio area with a fire pit, outdoor furniture, and a pergola.

An indoor swimming pool with lounge chairs and umbrellas, surrounded by walls with windows and doors.

A modern hotel lobby with a fireplace, seating area, and a 'Suite Shop' with refrigerated display cases.

A multi-story hotel with a prominent entrance, well-maintained landscaping, and a clear view of the hotel's name.

9. Homewood Suites by Hilton Buffalo Airport

Buffalo

CNY899

CNY1,023 total

includes taxes & fees

Oct 11 - Oct 12

A parking lot with cars and a covered walkway.

A Hyatt Place hotel with a modern facade, a well-lit entrance, and a parking lot.

A hotel room with a bed, a desk, a sofa, and a painting on the wall.

10. Hyatt Place Buffalo/Amherst

Buffalo

CNY1,080

CNY1,228 total

includes taxes & fees

Oct 11 - Oct 12

A hotel pool area with a hot tub, lounge chairs, and a seating area with tables.

An outdoor patio area with a stone fire pit surrounded by wicker furniture and cushions.

A modern bar area with a central island, bar stools, and a menu display.

A Courtyard by Marriott hotel with a covered entrance, brick facade, and multiple windows.

11. Courtyard Buffalo Airport

Buffalo

CNY1,049

CNY1,193 total

includes taxes & fees

Sep 20 - Sep 21

A buffet setup with various food items and utensils.

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

A hotel room with a sofa, a bed, a desk, and a chair. There are lamps on the desk and bedside tables.

12. Salvatores Grand Hotel

Buffalo

CNY1,134

CNY1,290 total

includes taxes & fees

Sep 18 - Sep 19

A pool area with a hot tub, lounge chairs, and a lifeguard chair.

A modern hotel lobby with a central bar area, seating arrangements, and pendant lighting.

A modern dining area with a round table, two chairs, and a pendant light.

13. Fairfield Inn & Suites by Marriott Buffalo Airport

Buffalo

CNY960

CNY1,092 total

includes taxes & fees

Sep 28 - Sep 29

A spacious lobby with a central seating area, a shop in the background, and potted plants along the walkway.

A large indoor swimming pool with clear blue water, surrounded by white pillars and blue-tiled edges.

A Hilton Garden Inn hotel with a well-lit entrance, outdoor seating area, and landscaped garden.

14. Hilton Garden Inn Buffalo Airport

Buffalo

CNY1,096

CNY1,247 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with a bed, desk, and a large mirror with built-in lighting.

A gym with treadmills, exercise bikes, and a mirrored wall.

A large industrial building with a silo-like structure and a tower on top, surrounded by calm water with several small boats.

A lobby area with a vending machine, snack shelves, seating, and a reception desk.

15. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Buffalo

CNY765

CNY870 total

includes taxes & fees

Oct 14 - Oct 15

An indoor swimming pool with clear water, lounge chairs, and a lifeguard stand.

A gym with a bench, dumbbells, and a treadmill.

A modern hotel lobby with a blue accent wall, a reception desk, a sofa, a chair, and a coffee table.

A modern dining area with yellow chairs, wooden tables, and a central counter with a coffee machine.

16. Comfort Inn & Suites Buffalo Airport

Buffalo

CNY749

CNY852 total

includes taxes & fees

Sep 30 - Oct 1

An indoor swimming pool with a water fountain, surrounded by greenery and modern architecture with a glass ceiling.

A hotel room with a bed, a TV mounted on the wall, a small table with a vase and candles, a chair, and a view of the city at night.

A lobby with a reception desk, seating area, and a patterned carpet.

A hotel room with a large bed, a chair, a desk, and a view of the outdoors.

17. M Hotel Buffalo

Buffalo

CNY692

CNY787 total

includes taxes & fees

Sep 20 - Sep 21

A hotel lobby with a bar area, seating arrangements, and large windows providing natural light.

A hotel reception desk with a 'Welcome to Buffalo' sign, framed pictures on the wall, and a 'Hilton Honors' sign.

A snack bar with refrigerated drinks, chips, and cookies.

A Hampton Inn & Suites with a clear entrance, a covered parking area, and a brick facade.

18. Hampton Inn & Suites Buffalo Airport

Buffalo

CNY875

CNY995 total

includes taxes & fees

Sep 30 - Oct 1

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

19. Wyndham Garden Buffalo Downtown

Downtown Buffalo

CNY997

CNY1,163 total

includes taxes & fees

Sep 20 - Sep 21

A bar area with multiple stools, a counter, and TVs displaying sports.

A hotel room with a beige sofa, a wooden coffee table, a TV, and a bed with a wooden headboard.

A hotel with a covered entrance, stone pillars, and a well-lit facade.

A gym with treadmills, elliptical machines, and weightlifting equipment.

20. Buffalo Airport Hotel

Buffalo

CNY585

CNY666 total

includes taxes & fees

Sep 20 - Sep 21

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Go beyond your typical stay in West Seneca

Top landmarks in West Seneca

Southgate Plaza

8.2/10 (45 reviews)

If you like shopping, take time out to go to Southgate Plaza when in West Seneca.

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Charles E. Burchfield Nature and Art Center

8.0/10 (21 reviews)

Why not give yourself a treat with a trip to Charles E. Burchfield Nature and Art Center, one of the family attractions located 1.3 mi (2 km) from central West Seneca. If you have fun at Charles E. Burchfield Nature and Art Center, you'll love Buffalo and Erie County Botanical Gardens and Holiday Twin Rinks, both located nearby.

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Learn more about West Seneca

Notable for its sports, West Seneca features attractions such as Southgate Plaza and Charles E. Burchfield Nature and Art Center.

See all hotels in West Seneca

Check out reviews of West Seneca hotels guests love

A two-story building with a porch and potted plants.

A compact hotel room with a bed, a small kitchenette, a dining area with a table and stools, and a living area with a sofa.

A compact kitchen with dark cabinetry, a dishwasher, a microwave, and a coffee maker.

A living room with a brown sofa, a kitchen area with a microwave, and a dining table with stools.

The Fields of Eden Inn

Eden

10/10 Exceptional

John

A hotel with a brick facade, multiple balconies, and a sign for 'The Mosey Hotel & Residences'.

A lobby with teal armchairs, a round table, a flat-screen TV, and a stone wall with a fireplace.

A modern lounge area with sofas, round tables, and a stone accent wall.

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

Buffalo

10/10 Exceptional

Marc

A two-story building with a white exterior, a red door, and large windows.

A hot tub with a wooden fence and a brick building in the background.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

Buffalo Guesthouse

Downtown Buffalo

10/10 Exceptional

Allan

Staybridge Suites West Seneca by IHG

Buffalo

10/10 Exceptional

Staybridge Suites exceeded all my expectations, and that is saying a lot for me. Not only was the room clean and comfortable, the towels were a good size, four pillows per bed, and a fully stocked kitchenette for our suite. I really liked that there was a tub in one bathroom and a step in shower in the other. That worked really well for our group. Highway noise was not an issue. There was a wide variety of breakfast items, hot and cold. The evening socials on Tuesday Wednesday and Thursday were...

Anonymous traveler