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Hotels in Santa Ana

September 2026
13
October 2026

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Sep 18 - Sep 20
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Sep 25 - Sep 27

Where to stay in Santa Ana?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santa Ana on Hotels.com. These Santa Ana hotels consistently deliver on quality, location and traveler experience. Last updated on September 13, 2026.
A hotel with a modern facade, a classical building with a dome in the background, and a well-lit entrance.
A modern lobby with a sofa, chairs, a coffee table, and a bar area with shelves and lighting.
An outdoor patio area with round tables and wicker chairs, surrounded by potted plants.
A view through a window of a building with a dome and classical architecture, a clear sky, and a distant mountain.

1. AC Hotel Cartagena

AC Hotel Cartagena
Casco Antiguo, 8.1 km from Santa Ana
United Kingdom
Christian
CNY860
CNY946 total
includes taxes & fees
Sep 20 - Sep 21
AC Hotel Cartagena
A hotel lobby with a reception desk, seating area, and a large skylight.
A hotel room with a bed, bedside table, lamp, and a television.
A modern living room with a black leather sofa, a round mirror, a desk, and a black rug.
A hotel entrance with a metal railing, potted plants, and a blue parking sign.

2. Hotel Manolo

Hotel Manolo
San Antonio Abad, 5.3 km from Santa Ana
United Kingdom
Robert
CNY474
CNY521 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Manolo
A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted TV.
A modern hotel lobby with a coffee bar, seating area, and a vending machine.
A modern hotel lobby with wooden paneling, comfortable seating, and large windows offering a view of the outdoors.
A modern hotel lobby with wooden paneling, comfortable seating, and large windows offering views of the outdoors.

3. Posadas de España Cartagena

Posadas de España Cartagena
Hondón, 7.3 km from Santa Ana
United Kingdom
Atanas
CNY531
CNY584 total
includes taxes & fees
Sep 16 - Sep 17
Posadas de España Cartagena
A modern bar area with a light wood finish, a coffee machine, and three bar stools.
A reception area with a modern design, featuring a white reception desk, green cushioned seating, and a large abstract mural on the wall.
A modern hotel building with a prominent 'NH Hotels' sign, a ground-level entrance, and a parking area with several cars.

4. NH Campo Cartagena

NH Campo Cartagena
Cartagena Casco, 6.9 km from Santa Ana
United Kingdom
Tracy
CNY495
CNY545 total
includes taxes & fees
Sep 20 - Sep 21
NH Campo Cartagena
A grand staircase with a chandelier, a wall with a building mural, and a modern interior design.
A hotel lobby with a grand chandelier, marble columns, a reception desk, and a staircase with metal railings.
A hotel room with a large bed, a bedside table with a lamp, a chair, a large mirror, and a window with curtains.
A bar area with a counter, bar stools, and a display of bottles and glasses.

5. Hotel Sercotel Alfonso XIII

Hotel Sercotel Alfonso XIII
Casco Antiguo, 7.3 km from Santa Ana
United Kingdom
David
CNY635
CNY698 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Sercotel Alfonso XIII
A bedroom with a bed, curtains, a TV, and a view of the outside.
A building with multiple balconies, each with green railings and flower boxes.
A modern kitchen with built-in cabinets, a dining area with a glass table, and a living space with a sofa and a plant.
A building with balconies, a garden with flowers, and a clear sky.

6. La Casa de las Flores

La Casa de las Flores
Casco Antiguo, 7.8 km from Santa Ana
United States
Deb
CNY1,031
CNY1,134 total
includes taxes & fees
Sep 30 - Oct 1
La Casa de las Flores
A room with a laptop on a round table, a TV mounted on the wall, and a potted plant.
A modern living room with a grey armchair, a blue sofa, a dining table with chairs, and a small potted plant.
A building entrance with a double door and a decorative metal gate.
A hotel room with a bed, a bedside table, a potted plant, and a window with curtains.

7. Apartamentos Turísticos Plaza del Rey

Apartamentos Turísticos Plaza del Rey
Casco Antiguo, 7.9 km from Santa Ana
United States
Cheryl
CNY469
CNY516 total
includes taxes & fees
Sep 14 - Sep 15
Apartamentos Turísticos Plaza del Rey
A hotel room with a large bed, a desk, a flat-screen TV, a coffee maker, and a window with curtains.
A modern hotel room with a round dining table, two chairs, a sofa, a lamp, and artwork on the walls.
A modern bathroom with a toilet, bidet, bathtub, and a large mirror.
A hotel room with a large bed, two bedside tables with lamps, a wall-mounted artwork, and a dark ceiling.

8. B&B Hotel Cartagena Cartagonova

B&B Hotel Cartagena Cartagonova
Casco Antiguo, 7.4 km from Santa Ana
United Kingdom
Linda
CNY490
CNY539 total
includes taxes & fees
Oct 4 - Oct 5
B&B Hotel Cartagena Cartagonova
A modern living room with a grey sofa, a round coffee table, and a dining area with a white table and chairs.
A modern kitchen with white cabinets, a wooden countertop, a built-in oven, and a stove.
A hallway with a wooden floor, a black console table with a mirror, and a potted plant.
A modern living room with a dark wooden dining table, two black chairs, a grey sofa, and a white coffee table.

9. Apartamentos Plaza Sevillano

Apartamentos Plaza Sevillano
Casco Antiguo, 7.6 km from Santa Ana
United States
Betty
CNY516
CNY516 total
includes taxes & fees
Sep 14 - Sep 15
Apartamentos Plaza Sevillano
A modern living room with a sofa, two armchairs, a wooden coffee table, and a TV on a stand.
A modern kitchen with white cabinetry, a stainless steel sink, a gas stove, and a coffee maker.
A neatly made bed with a brown and white bedspread, two framed pictures on the wall, and a bedside table with a lamp.
A modern kitchen with stainless steel appliances, a built-in washing machine, and a clean, minimalist design.

10. Puerta Real

Puerta Real
Casco Antiguo, 7.6 km from Santa Ana
United States
Mansour
CNY616
CNY655 total
includes taxes & fees
Sep 15 - Sep 16
Puerta Real
A bay window with a wooden table and two chairs, a potted plant, and a view of a hillside.
A modern kitchen with a white countertop, stainless steel sink, and a grey sofa in the living area.
A building with multiple balconies, a cobblestone street, and outdoor seating areas.
A hotel room with a bed, a green bedspread, two patterned pillows, and a window with a view of a building.

11. Apartamentos Turísticos Gran Vía

Apartamentos Turísticos Gran Vía
Casco Antiguo, 7.6 km from Santa Ana
United Kingdom
Lynn
CNY512
CNY551 total
includes taxes & fees
Sep 14 - Sep 15
Apartamentos Turísticos Gran Vía
A hallway with a stone wall, a wooden door, and a white tiled floor.
A building entrance with a clear pathway leading to a glass door.
A bathroom with a white sink, two potted plants, a round mirror above the sink, and a shower enclosure.
A hotel room with a bed, a bedside table with a lamp, a potted plant, and a window with curtains.

12. Apartamentos Turísticos Insulae

Apartamentos Turísticos Insulae
Casco Antiguo, 7.9 km from Santa Ana
Spain
Fatima
CNY469
CNY516 total
includes taxes & fees
Sep 14 - Sep 15
Apartamentos Turísticos Insulae
A swimming pool with a surrounding walkway, palm trees, and a sunset sky.
A rooftop pool area with a small hot tub, surrounded by palm trees and a view of distant hills.
A living room with a sofa, coffee table, and a ceiling fan. There is a window with blinds and a painting on the wall.
A spacious room with a wooden floor, a guitar, a mat, a small table with a speaker, and two potted plants.

13. Espacio Finca Alegría

Espacio Finca Alegría
Perín, 8 km from Santa Ana
France
Olivier
CNY433
CNY477 total
includes taxes & fees
Sep 14 - Sep 15
Espacio Finca Alegría
A view from a balcony with a wrought iron railing, overlooking ancient ruins and a grassy area.
A view of ancient ruins with modern buildings in the background.
A rustic dining area with a wooden table, chairs, and a cabinet.
A spacious living room with a large window, a wooden cabinet, and a television.

14. Apartamentos turísticos Teatro Romano

Apartamentos turísticos Teatro Romano
Casco Antiguo, 8 km from Santa Ana
Spain
Herme
CNY508
CNY508 total
includes taxes & fees
Sep 14 - Sep 15
Apartamentos turísticos Teatro Romano
A hotel entrance with a reception desk, seating area, and potted plants.
A hotel room with two beds, a desk, a TV, and a large window with curtains.
A spacious hotel lobby with a marble staircase, a reception desk, and a view of a dining area with tables and chairs.
A modern hotel entrance with a large potted plant, a reception desk, and a visible sign for 'Hotel Carlos III'.

15. Hotel Sercotel Carlos III

Hotel Sercotel Carlos III
Casco Antiguo, 7.4 km from Santa Ana
Canada
Richard
CNY510
CNY561 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Sercotel Carlos III
A hotel room with a bed, a desk, a mirror, a window, and a painting of a bus.
A multi-story building with a red brick facade, multiple balconies, and a corner entrance.
A kitchen with wooden cabinets, a white countertop, a sink, a stove, and a microwave.
A modern living room with a sofa, wooden cabinets, a TV, and a glass cabinet with cups and a wine glass.

16. Apartamentos Turísticos Distrito Romano

Apartamentos Turísticos Distrito Romano
Casco Antiguo, 7.8 km from Santa Ana
Spain
José A.
CNY439
CNY478 total
includes taxes & fees
Sep 16 - Sep 17
Apartamentos Turísticos Distrito Romano
A poolside view with a large pool, a covered seating area, and a multi-story building with balconies in the background.
An outdoor wedding aisle with wicker chairs and pampas grass decorations.
A multi-story hotel with a central entrance, balconies, and a swimming pool area.
A large indoor swimming pool with lounge chairs and patterned pillars.

17. Ona Mar Menor Golf & Spa

Ona Mar Menor Golf & Spa
11.3 km from Santa Ana
United Kingdom
Mark
CNY632
CNY695 total
includes taxes & fees
Sep 20 - Sep 21
Ona Mar Menor Golf & Spa
A living room with a brick wall, wooden floor, a sofa, a TV, a chair, and a small table.
A hotel room with a bed, a window, and a balcony.
A modern kitchen with white cabinets, a wooden countertop, a stainless steel sink, and a built-in washing machine.
A rooftop terrace with sun loungers, a table with chairs, and a view of the cityscape.

18. Apartamentos Decumano Romano

Apartamentos Decumano Romano
Casco Antiguo, 7.8 km from Santa Ana
United Kingdom
Michael
CNY469
CNY516 total
includes taxes & fees
Sep 14 - Sep 15
Apartamentos Decumano Romano
A modern living room with a sofa, a TV, a small table, and a balcony with a table and chairs.
A modern living room with a teal sofa, a wooden coffee table, and a colorful abstract painting.
A modern kitchen with a wooden island, two pendant lights, and stainless steel appliances.
A modern hotel room with a neatly made bed, a bedside table, and a wall-mounted artwork above the bed.

19. Apartamentos Turísticos Metrópolis

Apartamentos Turísticos Metrópolis
Casco Antiguo, 7.5 km from Santa Ana
Spain
Fatima
CNY539
CNY578 total
includes taxes & fees
Oct 4 - Oct 5
Apartamentos Turísticos Metrópolis
A modern living room with a sofa, a dining table, and a staircase.
A modern living room with a TV, a dining area, and a kitchen in the background.
A hotel room with a bed, two bedside lamps, a window with curtains, and a colorful abstract painting on the wall.
A modern living room with a sofa, a TV on a wooden stand, a small table, and a painting on the wall.

20. Apartamentos Centro Histórico

Apartamentos Centro Histórico
Casco Antiguo, 7.8 km from Santa Ana
United Kingdom
Linda
CNY447
CNY447 total
includes taxes & fees
Sep 14 - Sep 15
Apartamentos Centro Histórico
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Our prices for hotels in Cartagena are cheapest in January

Price trends for hotels in Cartagena

Pricing is based on two traveler single night rates
View properties in September

September

High 27°C / low 23°C. Sunny most days.
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Monthly weather averages (˚C)

Check out reviews of Santa Ana hotels guests love

A hotel with a modern facade, a classical building with a dome in the background, and a well-lit entrance.
A modern lobby with a sofa, chairs, a coffee table, and a bar area with shelves and lighting.
An outdoor patio area with round tables and wicker chairs, surrounded by potted plants.
A view through a window of a building with a dome and classical architecture, a clear sky, and a distant mountain.

AC Hotel Cartagena

AC Hotel Cartagena
Cartagena Casco

10/10 Exceptional

United States
Daniel
AC Hotel Cartagena
A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted TV.
A modern hotel lobby with a coffee bar, seating area, and a vending machine.
A modern hotel lobby with wooden paneling, comfortable seating, and large windows offering a view of the outdoors.
A modern hotel lobby with wooden paneling, comfortable seating, and large windows offering views of the outdoors.

Posadas de España Cartagena

Posadas de España Cartagena
Hondón

10/10 Exceptional

United States
Nigel
Posadas de España Cartagena
A grand staircase with a chandelier, a wall with a building mural, and a modern interior design.
A hotel lobby with a grand chandelier, marble columns, a reception desk, and a staircase with metal railings.
A hotel room with a large bed, a bedside table with a lamp, a chair, a large mirror, and a window with curtains.
A bar area with a counter, bar stools, and a display of bottles and glasses.

Hotel Sercotel Alfonso XIII

Hotel Sercotel Alfonso XIII
Cartagena Casco

10/10 Exceptional

United States
Cathy
Hotel Sercotel Alfonso XIII
An outdoor dining area with tables and chairs, palm trees, and a sign reading "MANDUKA".
A bedroom with a four-poster bed, a bedside table, a chair, a sofa, a television, and a door.
A multi-story hotel with a prominent "HOTEL" sign, multiple balconies, and a well-lit entrance.
A modern atrium with artwork on the walls, a glass staircase, and potted plants.

Atrium Hotel

Atrium Hotel
Bolnuevo

10/10 Exceptional

United States
Raongdao
Atrium Hotel
A beach with rocky outcrops and waves crashing onto the shore.
A modern building with a flat roof, large windows, and a covered entrance.
A neatly made bed with white and gray bedding, a dark headboard, and a bedside table with a lamp.
A wooden staircase with integrated lighting along the steps.

Hotel Portmán

Hotel Portmán
Portman

10/10 Exceptional

United States
gabor
Hotel Portmán
A large, clear blue pool with a modern architectural backdrop.
A modern hotel room with a large bed, a desk, and a view of a pool and palm trees.
A paved pathway lined with palm trees and benches, leading towards a body of water.
A well-maintained garden with palm trees, a grassy lawn, and a view of the sea.

Occidental Mar Menor

Occidental Mar Menor
El Algar

10/10 Exceptional

United States
Luis Hernando
Occidental Mar Menor
A bedroom with a bed, curtains, a TV, and a view of the outside.
A building with multiple balconies, each with green railings and flower boxes.
A modern kitchen with built-in cabinets, a dining area with a glass table, and a living space with a sofa and a plant.
A building with balconies, a garden with flowers, and a clear sky.

La Casa de las Flores

La Casa de las Flores
Cartagena Casco

10/10 Exceptional

United States
Anonymous traveler
La Casa de las Flores
A modern bar area with a light wood finish, a coffee machine, and three bar stools.
A reception area with a modern design, featuring a white reception desk, green cushioned seating, and a large abstract mural on the wall.
A modern hotel building with a prominent 'NH Hotels' sign, a ground-level entrance, and a parking area with several cars.

NH Campo Cartagena

NH Campo Cartagena
Cartagena Casco

10/10 Exceptional

United States
Richard
NH Campo Cartagena
A modern living room with a grey sofa, a round coffee table, and a dining area with a white table and chairs.
A modern kitchen with white cabinets, a wooden countertop, a built-in oven, and a stove.
A hallway with a wooden floor, a black console table with a mirror, and a potted plant.
A modern living room with a dark wooden dining table, two black chairs, a grey sofa, and a white coffee table.

Apartamentos Plaza Sevillano

Apartamentos Plaza Sevillano
Cartagena Casco

10/10 Exceptional

United States
Anandbabu
Apartamentos Plaza Sevillano
A room with a laptop on a round table, a TV mounted on the wall, and a potted plant.
A modern living room with a grey armchair, a blue sofa, a dining table with chairs, and a small potted plant.
A building entrance with a double door and a decorative metal gate.
A hotel room with a bed, a bedside table, a potted plant, and a window with curtains.

Apartamentos Turísticos Plaza del Rey

Apartamentos Turísticos Plaza del Rey
Cartagena Casco

10/10 Exceptional

United States
Cheryl
Apartamentos Turísticos Plaza del Rey
A modern living room with a sofa, two armchairs, a wooden coffee table, and a TV on a stand.
A modern kitchen with white cabinetry, a stainless steel sink, a gas stove, and a coffee maker.
A neatly made bed with a brown and white bedspread, two framed pictures on the wall, and a bedside table with a lamp.
A modern kitchen with stainless steel appliances, a built-in washing machine, and a clean, minimalist design.

Puerta Real

Puerta Real
Cartagena Casco

10/10 Exceptional

United States
Mark
Puerta Real
A hotel room with a large bed, a desk, a flat-screen TV, a coffee maker, and a window with curtains.
A modern hotel room with a round dining table, two chairs, a sofa, a lamp, and artwork on the walls.
A modern bathroom with a toilet, bidet, bathtub, and a large mirror.
A hotel room with a large bed, two bedside tables with lamps, a wall-mounted artwork, and a dark ceiling.

B&B Hotel Cartagena Cartagonova

B&B Hotel Cartagena Cartagonova
Cartagena Casco

10/10 Exceptional

United States
Benjamin
B&B Hotel Cartagena Cartagonova

Frequently Asked Questions

Is Santa Ana expensive to stay in?

You can find great hotels from CNY349 in Santa Ana to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".

How can I find discounted rates and deals for Santa Ana hotels?

Discover great deals on hotels in Santa Ana with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Ana hotels.

Can I receive a refund if I cancel my Santa Ana hotel booking?

The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".

Is it worth staying in Santa Ana?

Basing yourself in Santa Ana makes it easy to explore Cartagena, including the neighborhoods of Cartagena Casco and Perín.

Keep exploring