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Hotels in Southeast Illinois

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Where to stay in Southeast Illinois?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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You may also like family-friendly hotels in Southeast Illinois

You can also stay at pet-friendly hotels in Southeast Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Southern Illinois

Learn more about Southeast Illinois

Southeast Illinois is hailed for its casinos and university life while top attractions include Ohio River Valley. This family-friendly city has something for everyone including its entertainment, restaurants, and sights like Lake Sara and Effingham Performance Center.

Fort Massac State Park featuring a lake or waterhole, a statue or sculpture and a park
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

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There are plenty of reasons to book your Southeast Illinois travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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