Hotels in Southwest Illinois

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Check prices for these dates

Tonight
May 9 - May 10
Tomorrow
May 10 - May 11
This weekend
May 9 - May 11
Next weekend
May 16 - May 18

Where to stay in Southwest Illinois?

Drury Plaza Hotel Mt. Vernon
Lobby

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1309)
The price is CNY911
CNY1,025 total
includes taxes & fees
May 28 - May 29
Drury Plaza Hotel Mt. Vernon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southwest Illinois, IL

Showing deals for:May 16 - May 18

Image gallery for Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

Lobby sitting area

Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

3.0 star property
O'Fallon
8.0/10Very Good (858 reviews)
10% off
Price is CNY1,522
per night
CNY3,531 total
includes taxes & fees
Hilton Garden Inn St. Louis Shiloh/O'Fallon IL

Top landmarks in Southwest Illinois

Campus Lake at Southern Illinois University in Carbondale, IL.

Southern Illinois University

If you'd like to get a taste of Carbondale student life, check out Southern Illinois University, located 1.1 mi (1.7 km) from central Carbondale.

See properties in Southern Illinois University
Southern Illinois University

Learn more about Southwest Illinois

Southwest Illinois is applauded for its entertainment and live music with such cultural attractions as Popeye Museum and Henry N Barkhausen Cache River Wetlands Center. The city has something for everyone including its sports, restaurants, and sights like DuQuoin State Fairgrounds and Rend Lake.

See all hotels in Southwest Illinois
Southern Illinois which includes a lake or waterhole and forests
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Frequently asked questions

Can I book refundable accommodations in Southwest Illinois?
If you’re looking for the flexibility to change your travel plans to Southwest Illinois, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Southwest Illinois if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 193 vacation homes. In addition, there are 70 apartments and 5 condos.
Why should I book my Southwest Illinois hotel through Hotels.com?
There are plenty of reasons to book your Southwest Illinois travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.