Photo by Jake Blucker

Hotels in Southeast Ohio

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Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Where to stay in Southeast Ohio?

Lobby sitting area
Garland Hotel
Garland Hotel
2.5 star property
9.0 out of 10, Wonderful, (952)
The price is CNY564
CNY644 total
includes taxes & fees
Dec 22 - Dec 23
Garland Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southeast Ohio, OH

Showing deals for:Jan 2 - Jan 4

Image gallery for Jungle House Luxury Stays - Downtown Chillicothe

Interior

Jungle House Luxury Stays - Downtown Chillicothe

4.0 star property
Chillicothe
8.8/10Excellent (8 reviews)
30% off
Price is CNY779
CNY2,117 total
includes taxes & fees
Jungle House Luxury Stays - Downtown Chillicothe

Check out hotels with a spa in Southeast Ohio

Exterior
The Blennerhassett Hotel

The Blennerhassett Hotel

The Blennerhassett Hotel
3.5 star property
Parkersburg
9.4 out of 10, Exceptional, (1003)
The price is CNY944
CNY1,099 total
includes taxes & fees
Dec 31 - Jan 1, 2026
The Blennerhassett Hotel
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You may also like hotels with hot tubs in Southeast Ohio

Indoor pool
Quality Inn & Suites Zanesville City Center

Quality Inn & Suites Zanesville City Center

Quality Inn & Suites Zanesville City Center
2.5 star property
Zanesville
8.8 out of 10, Excellent, (512)
The price is CNY602
CNY688 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Quality Inn & Suites Zanesville City Center
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You can also stay at family-friendly hotels in Southeast Ohio

Lobby
Microtel Inn & Suites by Wyndham Cambridge

Microtel Inn & Suites by Wyndham Cambridge

Microtel Inn & Suites by Wyndham Cambridge
2.0 star property
Cambridge
8.4 out of 10, Very Good, (1002)
The price is CNY473
CNY550 total
includes taxes & fees
Dec 28 - Dec 29
Microtel Inn & Suites by Wyndham Cambridge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Southeast Ohio

Called "The Ridges" currently, this large, looming building that overlooks Ohio University's campus was formerly a mental health hospital called the Athens Asylum for the Insane. There's a small museum inside now, and the rest of the grounds are owned by the university, but there is still certainly a chilling aspect to the building that calls to its past. Take a walk around the grounds or visit the museum, it's something worth seeing. Behind the building is a community park with areas that would be worth visiting in warmer days. Take the road that loops up a hill (to the left of a campus sign) and you can view the cemetery of unnamed, forgotten patients who died and were only assigned a number. There are efforts to find the names of these individuals and give them the attention that is deserved. There's also a beautiful nature walk that I would have taken if it wasn't so cold! #roadtrips #ohio #historic #hospitals #roadtrip
Photo by Erica R Hopper
Open Photo by Erica R Hopper

Ohio University

4.7/5 (376 reviews)
If you'd like to get a taste of Athens student life, check out Ohio University, located 0.3 mi (0.5 km) from central Athens.
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Since its completion in 1924, Swasey Chapel has been Denison’s most iconic structure. The chapel seats 990 and plays host to notable campus events such as baccalaureate services, lectures, concerts, and academic award convocations.
Photo by throwingsofas
Open Photo by throwingsofas

Denison University

4.6/5 (101 reviews)
If you'd like to get a taste of Granville student life, check out Denison University, located 0.3 mi (0.5 km) from central Granville.
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Learn more about Southeast Ohio

Southeast Ohio is hailed for its university life and festivals while top attractions include Hocking Hills State Park. This family-friendly city has something for everyone including its sports, restaurants, and sights like Wayne National Forest Athens Unit and Burr Oak State Park.

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The Upper Falls
Photo by Jake Blucker
Open Photo by Jake Blucker

Check out reviews of Southeast Ohio hotels guests love

Days Inn by Wyndham Columbus East Airport

Days Inn by Wyndham Columbus East Airport

10/10 Excellent
"Good stay overall. "
Tevin 1-night trip
Posted 5 days ago
Days Inn by Wyndham Columbus East Airport

Frequently asked questions

Why should I book my Southeast Ohio accommodation with Hotels.com?
There are plenty of reasons to book your Southeast Ohio travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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