Santa Cruz Hotels

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Apr 14 - Apr 15
Tomorrow
Apr 15 - Apr 16
This weekend
Apr 17 - Apr 19
Next weekend
Apr 24 - Apr 26

Where to stay in Santa Cruz

Top hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
9/10 Wonderful! (365 reviews)
SEE MORE PROPERTIES

Top hotels in Samaipata

El Pueblito Hotel Boutique

El Pueblito Hotel Boutique

3 out of 5
9.8/10 Exceptional! (19 reviews)

Top hotels in Warnes

Hotel Rio Selva Resort Santa Cruz

Hotel Rio Selva Resort Santa Cruz

3 out of 5
Terramia Resort

Terramia Resort

3.5 out of 5

Top hotels in San Jose de Chiquitos

La Villa Chiquitana

La Villa Chiquitana

4 out of 5
9.2/10 Wonderful! (7 reviews)

Top cities in Santa Cruz

Image for Santa Cruz

Santa Cruz

Santa Cruz has lots of attractions such as Plaza 24 de Septiembre and Municipal Library.
See properties
Santa Cruz

Great weekend hotel deals in Santa Cruz

Showing deals for:Apr 24 - Apr 26

Image gallery for Casa Por Temporadas

BBQ/picnic area

Casa Por Temporadas

2.0 star property
Santa Cruz
10/10Exceptional (1 review)
Member Price available
Price is CNY584
CNY1,168 total
Casa Por Temporadas

Top landmarks in Santa Cruz

Plaza 24 de Septiembre

4.4/5 (164 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.
See properties

San Lorenzo Cathedral

4.5/5 (84 reviews)
San Lorenzo Cathedral is in the heart of Santa Cruz, so why not stop by during your stay.
See properties

Check out the Santa Cruz hotels guests love right now

Prince Hotel

Prince Hotel

10/10 Excellent
"Very inexpensive and clean "
Carlos 7-night trip
Posted 4 days ago
Prince Hotel

Find out more about Santa Cruz