Hotels in Mission District

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Where to stay in Mission District?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Mission District on Hotels.com. These Mission District hotels consistently deliver on quality, location and traveler experience. Last updated on September 25, 2026.

A wooden deck with a table set for two, featuring a plate of food and a cup of coffee.

A bedroom with a large bed, a round table, and a chair, with a view of trees through the window.

A room with a grand piano, two striped armchairs, a fireplace, and a large painting.

A wooden desk with a chair, a television mounted on the wall, and a window with a view of greenery outside.

1. Noe's Nest Bed and Breakfast

Mission District

Zachariah

CNY1,813

CNY2,108 total

includes taxes & fees

Oct 20 - Oct 21

A wooden outdoor bar set with a variety of snacks, wine glasses, and bottles in a bucket.

A spacious living room with a grand piano, a staircase, and a cozy seating area.

A living room with a fireplace, a sofa, a coffee table, and a chair.

A kitchen with white cabinets, a microwave, and a decorative tray with a glass jar and flowers.

2. Parker Guest House San Francisco

Mission District

Colleen

CNY1,470

CNY1,713 total

includes taxes & fees

Sep 28 - Sep 29

A hallway with a wooden ceiling, a table with chairs, a potted plant, and framed pictures on the walls.

A modern living room with a wooden dining table, brown chairs, a sofa with cushions, a large window, and a brick accent wall.

A hotel room with a large bed, a wooden headboard, a window with curtains, and a small table with a vase.

A window seat with a cushion featuring a cityscape design, curtains, and a view of buildings and a street.

3. 1906 Mission

Mission District

Cristobal

CNY671

CNY781 total

includes taxes & fees

Oct 25 - Oct 26

A multi-story building with a corner entrance, a massage parlor, and a hotel named 'Hotel Sunrise' with a red awning.

A hallway with blue walls and white trim, featuring doors with numbers and a tiled floor.

A row of stacked front-loading washing machines with digital displays and operating instructions.

A long, narrow hallway with white wainscoting and blue walls, leading to a staircase at the end.

4. Hotel Sunrise

Mission District

Jason

CNY631

CNY734 total

includes taxes & fees

Oct 1 - Oct 2

A single bed with a white pillow and a mustard-colored blanket.

A nighttime cityscape with a prominent building featuring a red neon sign.

A narrow hallway with a door leading to a bright outdoor area.

A staircase with dark carpeting and a pink handrail.

5. Union Hotel

Mission District

Oscar

CNY430

CNY501 total

includes taxes & fees

Sep 28 - Sep 29

An outdoor seating area with wicker furniture and a fire feature, adjacent to a bar and dining area with modern decor.

A modern kitchen with wooden cabinets, white countertops, and a central island with fruits and jars.

A modern bar area with multiple seating options, a bar counter, and a television screen.

A modern lounge area with sofas, armchairs, and tables.

6. Hyatt Place San Francisco Downtown

3 km from Mission District

sarah

CNY1,309

CNY1,541 total

includes taxes & fees

Oct 16 - Oct 17

A spacious lobby with large windows, a seating area with a sofa and chairs, and a counter with a coffee station.

A modern hotel with a glass facade, large windows, and a vibrant, illuminated exterior.

A hotel room with a large bed, a desk, a chair, and a view of the city through large windows.

A modern reception area with a large screen displaying a desert landscape, wooden reception desk, comfortable seating, and a large window offering a view.

7. LUMA Hotel San Francisco

2.9 km from Mission District

Patti

CNY1,645

CNY1,936 total

includes taxes & fees

Oct 2 - Oct 3

A rooftop pool area with blue seating and a pool.

A spacious restaurant with multiple tables and chairs, large windows, and a modern interior design.

A modern hotel lobby with teal chairs, a large TV screen, and a decorative wall with shelves.

A hotel room with two beds, a desk, a chair, and a large window offering a city view.

8. Holiday Inn Golden Gateway by IHG

Nob Hill, 3.4 km from Mission District

Sally

CNY1,020

CNY1,201 total

includes taxes & fees

Oct 25 - Oct 26

A buffet counter with coffee machines, a TV, and various food items.

The Stanyan Park Hotel facade with a prominent entrance, large windows, and two potted trees.

A cozy living room with a sofa, chairs, a coffee table, a fireplace, and a television.

A golf course with a pond, trees, and a path.

9. Stanyan Park Hotel

3.4 km from Mission District

"The room was clean, carpet outdated and not my favorite in a hotel. The staff was friendly and helpful. They are able to hold your luggage upon check out, so you can continue to explore the city. Parking is located across the street near the police station, for a very reasonable fee. The area is quite and walkable, with Golden Gate Park across the street. On my next visit into the city I would definitely stay here rather than downtown."

Kelly

CNY1,408

CNY1,638 total

includes taxes & fees

Sep 27 - Sep 28

An indoor swimming pool with multiple lounge chairs and a high ceiling with skylights.

A spacious lobby with a blue sofa, armchairs, and a patterned carpet.

A multi-story hotel with a classic facade, large windows, and a prominent entrance.

A spacious living area with a city view, modern furniture, and a patterned carpet.

10. Hotel Nikko San Francisco

Union Square, 3 km from Mission District

Maurice

CNY1,421

CNY1,981 total

includes taxes & fees

Oct 2 - Oct 3

A modern hotel with a sleek exterior and a parked sports car in front.

A rooftop bar with outdoor seating, a view of the cityscape, and a clock tower in the background.

A modern lobby with a curved sofa, round tables, a reception desk, and a large blue wall feature.

A modern restaurant with multiple dining tables and chairs, a cityscape mural on the wall, and pendant lighting.

11. Hotel VIA

3.2 km from Mission District

Maria

CNY1,384

CNY1,628 total

includes taxes & fees

Oct 4 - Oct 5

A high-rise room with a city view, a sofa, two chairs, a small table, and a patterned rug.

A modern bar with a long counter, bar stools, and a bartender. There are shelves with bottles and glasses, and a view of the city through large windows.

A table with a glass of amber liquid, a plate of small pastries, and a cityscape view through large windows.

A woman sitting by a window with a city view, holding a glass of wine and a pink bag.

12. Hilton San Francisco Union Square

Union Square, 3 km from Mission District

rodney

CNY1,095

CNY1,289 total

includes taxes & fees

Oct 23 - Oct 24

A spacious lobby with modern seating, a large abstract sculpture, and a high ceiling with linear lighting.

A spacious lobby with a large abstract sculpture, tiered seating, and modern lighting fixtures.

A modern interior with a central escalator, multiple levels, and a distinctive sculpture.

A high-rise building with a view of a waterfront promenade, a clock tower, and a bridge in the distance.

13. Hyatt Regency San Francisco

Financial District, 4.3 km from Mission District

"Staff are welcoming and helpful. The location is convenient to public transportation, there is a BART station just steps away. The hotel is within walking distance to Union Square, the Ferry Building, or for a stroll along the promenade with a view of the water. Guests of the hotel can enjoy 10% discount from the restaurants in the Embarcadero complex. One not to miss is the excellent Harborview Chinese restaurant. Nearby there is a bus stop that will take you to Chinatown. Inside the Ferry...

LOUELYN

CNY1,470

CNY2,039 total

includes taxes & fees

Sep 27 - Sep 28

A staircase with ornate black metal railings and marble steps.

A modern office space with a glass partition, wooden flooring, and contemporary furniture.

A modern living room with a sofa, coffee table, and a TV mounted on the wall.

A room with a large window overlooking a cityscape at night.

14. YOTEL San Francisco, Select by Hilton

2.4 km from Mission District

Rodolfo

CNY879

CNY1,311 total

includes taxes & fees

Oct 25 - Oct 26

A multi-story hotel with a prominent sign reading "The Handlebar Union Square Hotel."

A hotel reception area with a reception desk, seating area, and a patterned carpet.

A hotel room with a large bed, a desk, a chair, a small table, and a TV.

15. Handlery Union Square Hotel

Union Square, 3.2 km from Mission District

Peter

CNY1,081

CNY1,272 total

includes taxes & fees

Oct 25 - Oct 26

A cityscape at dusk with illuminated buildings and a clear view of the skyline.

A bridge over water with a beach in the foreground.

A corner room with three large windows offering a city skyline view, a round wooden table with a lamp, and a blue chair.

A modern kitchen with a central island, bar stools, and a variety of food items and beverages.

16. Stanford Court San Francisco

Nob Hill, 3.7 km from Mission District

Stephen

CNY1,402

CNY1,951 total

includes taxes & fees

Oct 16 - Oct 17

A grand lobby with high ceilings, chandeliers, and a fireplace.

A hallway with a Christmas tree and nutcracker statues.

A grand lobby with a checkered floor, a blue sofa, and a chandelier.

A person with a suitcase at the entrance of a building with a blue wall and a decorative door.

17. The Marker Union Square San Francisco

3.1 km from Mission District

"We chose this hotel for its affordable price and location just half a mile from the Convention Center. The Marker has great style - two lovely sitting rooms with fireplaces on the first floor and a great bar and restaurant. The staff were really kind and well informed about the city, including mass transit. I took great walks from here to Fisherman’s Ward and several museums and interesting neighborhoods. There’s a fun live music club called Biscuits and Blues and a great diner, Dave’s, within...

Ariel

CNY988

CNY1,163 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a seating area, a bar, and large windows.

A modern interior with wooden flooring, a kitchen area, and a display case with snacks.

An outdoor seating area with wicker furniture, a glass-top fire pit, and potted plants.

A modern hotel lobby with a central seating area, a reception desk, and a staircase leading to upper floors.

18. Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf, 5.4 km from Mission District

Sarah

CNY860

CNY1,289 total

includes taxes & fees

Oct 18 - Oct 19

A lobby with a chandelier, seating area, and large mirrors.

A spacious library with wooden bookshelves, comfortable seating, and large windows allowing natural light.

A high-rise hotel room with a city view, leather sofas, patterned ottomans, and a leopard print rug.

A grand lobby with a chandelier, sofas, and a staircase.

19. Beacon Grand, A Union Square Hotel

Union Square, 3.4 km from Mission District

Jeffrey

CNY1,151

CNY1,663 total

includes taxes & fees

Oct 24 - Oct 25

A hotel room with a bed, a sofa, a small table, a chair, and a desk.

A corner of a room with a chair, a table with magazines, a window with a view of the street, and a thermostat.

A hotel room with a desk, a chair, a TV, and a microwave.

A hotel room with a flat-screen TV, a desk with a chair, a sofa, and a large window with curtains.

20. Symphony Inn

2.1 km from Mission District

Justin

CNY779

CNY908 total

includes taxes & fees

Oct 27 - Oct 28

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Our prices for hotels in Mission District are cheapest in April

Top landmarks in Mission District

A park with people sitting on the grass, a school building, and a cityscape in the background.

Mission Dolores Park

9.4/10 (3 reviews)

Mission Dolores Park is worth a pic or two when discovering Mission District. Let yourself be amazed at the art galleries and museums in the area too. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.

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A colorful street with murals, potted plants, and a brick sidewalk.

Balmy Alley

Mission District is home to Balmy Alley, so why not stop by during your stay in San Francisco. Let yourself be amazed at the art galleries and museums in the area too. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. San Francisco has lots of other important landmarks you might want to see such as Golden Gate Bridge.

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An interior of a church with arched ceilings, stained glass windows, and rows of pews.

Mission San Francisco de Asís

If you're interested in local religious buildings head to Mission District— home to Mission San Francisco de Asís. Our travelers also love the art galleries and museums in the area— your sightseeing tour starts here. San Francisco has other landmarks you might want to visit such as Golden Gate Bridge.

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Southern Exposure

If museums are on your list, you might want to check out the upcoming exhibitions at Southern Exposure in Mission District. Hotels.com travelers also love the art galleries in the area— your cultural tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you want to see more of the museums in San Francisco, Asian Art Museum of San Francisco and San Francisco Museum of Modern Art aren't far.

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The Great Northern

If the club scene floats your boat, dance the night away at The Great Northern in Mission District.

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Victoria Theatre

If you want to see a show while you're in town, try and grab some tickets at Victoria Theatre in Mission District. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you enjoy the show and want to see another, Brick & Mortar Music Hall and The Chapel are both a short walk away.

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Mission High School

If you're planning a bit of sightseeing head to Mission High School— just one of the monuments in Mission District. Our travelers also love the museums and art galleries in the area— your sightseeing tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. San Francisco has other landmarks you might want to visit such as Golden Gate Bridge.

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SF Armory

If you're planning a bit of sightseeing head to SF Armory— just one of the monuments in Mission District. Our travelers also love the art galleries and museums in the area— your sightseeing tour starts here. San Francisco has other landmarks you might want to visit such as Golden Gate Bridge.

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Check out reviews of Mission District hotels guests love

Hyatt Regency San Francisco

10/10 Excellent

"The buffet breakfast was good but not worth $40."

Club Quarters Hotel Embarcadero, San Francisco

10/10 Excellent

"Nice room, great breakfast, clean hotel, friendly staff"

Hyatt Regency San Francisco Downtown SOMA

8/10 Good

"Good location and helpful staff"

Hotel Zephyr San Francisco

10/10 Excellent

"Parking is way too much! Everything else is good!!"

Grand Hyatt San Francisco

8/10 Good

"Hotel is in the center of Union Square ..A fellow Filipina who checked us in gave us a room with a very nice view of sunset. She's very helpful and accommodating"

Frequently asked questions

Is Mission District expensive to stay in?

You can find great hotels from CNY501 in Mission District to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".

How can I find discounted rates and deals for Mission District hotels?

Discover great deals on hotels in Mission District with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Mission District hotels.

Can I receive a refund if I cancel my Mission District hotel booking?

The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Mission District hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".

What are some of the best pet-friendly hotels in Mission District?

Traveling with your pet doesn't mean sacrificing a great hotel stay. In Mission District, our travelers love:

Noe's Nest Bed and Breakfast has an average guest rating of 9.4 out of 10. To find more pet-friendly stays on Hotels.com, use the "Amenities" filter in your search and select "Pet friendly".

Is it worth staying in Mission District?

You're spoilt for choice with 66 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Mission District makes it easy to explore San Francisco, including the neighborhoods of Fisherman's Wharf and Union Square.

Which station is best for Mission District?

If you're staying at a hotel in Mission District, check out the nearest station so that you can get around and explore with ease. Stations in Mission District include:

16th Street Mission Station
24th Street Mission Station
Church St & 16th St Stop

What are some great hotels in Mission District with balconies?

There are some top hotels in Mission District that offer rooms with a balcony. Check out Parker Guest House San Francisco which has a high guest score of 9.6 out of 10, and balconies in some rooms.

Find out more about Mission District

Keep exploring

Book Hotels in Mission District on Hotels.com

Hotels in Mission District

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Mission District?

1. Noe's Nest Bed and Breakfast

2. Parker Guest House San Francisco

3. 1906 Mission

4. Hotel Sunrise

5. Union Hotel

6. Hyatt Place San Francisco Downtown

7. LUMA Hotel San Francisco

8. Holiday Inn Golden Gateway by IHG

9. Stanyan Park Hotel

10. Hotel Nikko San Francisco

11. Hotel VIA

12. Hilton San Francisco Union Square

13. Hyatt Regency San Francisco

14. YOTEL San Francisco, Select by Hilton

15. Handlery Union Square Hotel

16. Stanford Court San Francisco

17. The Marker Union Square San Francisco

18. Hotel Riu Plaza Fisherman's Wharf

19. Beacon Grand, A Union Square Hotel

20. Symphony Inn

Price trends for hotels in Mission District

Typical weather for San Francisco

Top landmarks in Mission District

Mission Dolores Park

Balmy Alley

Mission San Francisco de Asís

Southern Exposure

The Great Northern

Victoria Theatre

Mission High School

SF Armory

Check out reviews of Mission District hotels guests love

Hyatt Regency San Francisco

Club Quarters Hotel Embarcadero, San Francisco

Hyatt Regency San Francisco Downtown SOMA

Hotel Zephyr San Francisco

Grand Hyatt San Francisco

Frequently asked questions

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