Hotels in Southwest Illinois

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Where to stay in Southwest Illinois?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Southwest Illinois

Learn more about Southwest Illinois

Southwest Illinois is applauded for its entertainment and live music with such cultural attractions as Popeye Museum and Henry N Barkhausen Cache River Wetlands Center. The city has something for everyone including its sports, restaurants, and sights like DuQuoin State Fairgrounds and Rend Lake.

Southern Illinois which includes a lake or waterhole and forests
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Frequently asked questions

Can I book refundable accommodations in Southwest Illinois?
If you’re looking for the flexibility to change your travel plans to Southwest Illinois, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Southwest Illinois if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 193 vacation homes. In addition, there are 70 apartments and 5 condos.
Why should I book my Southwest Illinois hotel through Hotels.com?
There are plenty of reasons to book your Southwest Illinois travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.