Hotels in Irene

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Dates

April 2026

May 2026

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Where to stay in Irene?

Super 8 by Wyndham Beresford

Beresford

Stay close to Sioux Falls Regional Airport at this Beresford motel with free perks.

CNY509 total

includes taxes & fees

Apr 24 - Apr 25

Best Western Kelly Inn

Yankton

Comfort and convenience await in Yankton with a poolside retreat and American cuisine.

CNY747 total

includes taxes & fees

Mar 31 - Apr 1

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, free WiFi, bed sheets

Yankton Inn

Yankton

Stay in Yankton with comfort, ease, and friendly staff to assist your journey.

CNY597 total

includes taxes & fees

Mar 29 - Mar 30

Suite, 2 Queen Beds, Non Smoking | In-room safe, desk, soundproofing, iron/ironing board

Econo Lodge Inn & Suites Yankton

Yankton

Quiet riverside hotel with an indoor pool and hot tub for Yankton adventurers.

CNY523 total

includes taxes & fees

Mar 31 - Apr 1

Holiday Inn Express & Suites Yankton by IHG

Yankton

Relax in a riverside town near Fox Run Plaza with free breakfast and swim time.

CNY834 total

includes taxes & fees

Apr 16 - Apr 17

Fairfield Inn & Suites by Marriott Yankton

Yankton

Discover a comfortable retreat in Yankton with a refreshing indoor pool and attentive staff.

CNY979 total

includes taxes & fees

Mar 29 - Mar 30

Room, 1 King Bed, Accessible, Non Smoking | Premium bedding, down comforters, desk, laptop workspace

Comfort Inn Yankton SD

Yankton

CNY729 total

includes taxes & fees

Apr 19 - Apr 20

Family Quadruple Room | Living area | 32-inch LCD TV with digital channels, TV

Lewis and Clark Resort

Yankton

Perfect choice for boaters with direct marina and lake access in scenic Yankton.

CNY612 total

includes taxes & fees

Mar 26 - Mar 27

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Go beyond your typical stay in Irene

Apartment

Family friendly

Check out reviews of Irene hotels guests love

Comfort Inn Yankton SD

8/10 Good

"A lot of noise could be heard thrkugh walls.... even in King Suite. Parkin was good. Overall a very nice stay."

Best Western Kelly Inn

4/10 Poor

"Seriously, folks, we must have stayed when the hotel was understaffed. The bed in our room had a yellowish wet spot in the middle of the mattress which forced us to switch rooms. The “fitted” bed sheets were placed 90 degrees the wrong way and kept coming off. The toilet seat was not fastened to the toilet. The room frig’s 4-inch wide freezer was iced over so much that you could only fit something 1-inch wide in it. The hallways were messy. The only redeeming quality was the honest efforts of the high school staff to help correct things. PS, don’t go to the attached restaurant on karaoke night unless you’re deaf, because the screechy voices of the locals will impair your hearing, which apparently was the reason why the DJ had the volume so high. "

Frequently asked questions

How much does a hotel room cost in Irene?

You can choose a great hotel in Irene from CNY509 with properties to suit all budgets and needs. If you're after an affordable hotel in Irene that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Irene hotels?

Discover great deals on Irene hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Irene hotels.

Can I book Irene hotels with free cancellation?

It's easy to book a refundable Irene hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book refundable hotels in Irene?

If you're looking for the flexibility to change your plans to Irene, most accommodations provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Irene be like during my vacation?

July and August are typically the warmest months in Irene when the average temp is 72°F. January and February are the coldest months when the average temperature is 26°F. June and May are the months with the most rain.

Why should I book my Irene accommodation with Hotels.com?

There are lots of reasons to book your Irene trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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