Hotels in Puxico

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
May 8 - May 9
Tomorrow
May 9 - May 10
This weekend
May 8 - May 10
Next weekend
May 15 - May 17

Where to stay in Puxico?

Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Dexter
Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (260 reviews)
This motel offers a cozy overnight stop with easy access to The Heritage House and Dexter Welcome Center. Guests praise the attentive staff who ensure a comfortable stay while enjoying convenient amenities and business-friendly services.
The price is CNY347
CNY389 total
includes taxes & fees
Jun 7 - Jun 8
Econo Lodge Dexter
Lobby sitting area
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (90 reviews)
Adventure seekers can explore nearby hiking trails, kayaking, and rafting, then return to this welcoming hotel. Enjoy free continental breakfast, WiFi, and parking, plus exceptional service from the staff that guests consistently praise.
The price is CNY637
CNY693 total
includes taxes & fees
May 10 - May 11
EC Reed's Mercantile and Hotel
Breakfast, lunch, dinner served; American cuisine
Travelodge by Wyndham Dexter
Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (402 reviews)
Walking distance to The Heritage House and Keller Veteran Memorial, this hotel boasts free WiFi and parking. Enjoy American cuisine at Penny's Diner, open for 3 daily meals, plus 24-hour front desk service for round-the-clock assistance.
The price is CNY591
CNY663 total
includes taxes & fees
May 25 - May 26
Travelodge by Wyndham Dexter
Breakfast area
Dexter Inn
Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (344 reviews)
Near local attractions like The Heritage House and Keller Veteran Memorial, this welcoming hotel offers complimentary WiFi and parking. Unwind in the seasonal outdoor pool after exploring, with a staff that guests consistently praise for their exceptional service.
The price is CNY408
CNY458 total
includes taxes & fees
May 10 - May 11
Dexter Inn
Desk, iron/ironing board, free WiFi, bed sheets
OYO Hickory House Inn
OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (138 reviews)
Cozy rooms with convenient amenities await at this budget-friendly Dexter accommodation. Enjoy complimentary WiFi, free parking, and room service while staying minutes from The Heritage House and Keller Veteran Memorial.
The price is CNY337
CNY412 total
includes taxes & fees
May 24 - May 25
OYO Hickory House Inn
Lobby
Hampton Inn By Hilton Dexter
Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (25 reviews)
The price is CNY608
CNY683 total
includes taxes & fees
May 17 - May 18
Hampton Inn By Hilton Dexter
Lobby
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,008 reviews)
Minutes from North Main Street Historic District, this peaceful hotel offers 2 swimming pools and fitness options. Guests rave about the quiet atmosphere, complimentary breakfast, and exceptionally helpful staff. Free WiFi and parking enhance your comfortable Missouri stay.
The price is CNY639
CNY722 total
includes taxes & fees
Jun 7 - Jun 8
Drury Inn & Suites Poplar Bluff
Lobby
Comfort Inn Poplar Bluff North
Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (411 reviews)
Minutes from Poplar Bluff Station, this tranquil hotel offers a 24-hour fitness center and seasonal outdoor pool. Clean rooms provide a restful retreat after exploring nearby North Main Street Historic District and Margaret Harwell Art Museum.
The price is CNY540
CNY610 total
includes taxes & fees
May 17 - May 18
Comfort Inn Poplar Bluff North
Front of property
Lake Wappapello
Lake Wappapello
2.0 star property
Williamsville
10.0 out of 10, Exceptional, (2 reviews)
Rustic cabins equipped with refrigerators and microwaves create a homey retreat at Lake Wappapello. Just a short drive from Poplar Bluff Station and North Main Street Historic District, this peaceful lakeside haven offers free parking.
The price is CNY578
CNY610 total
includes taxes & fees
Jun 7 - Jun 8
Lake Wappapello
Reception
Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (832 reviews)
Wake up to a tasty free breakfast at this Poplar Bluff hotel with indoor pool and fitness center. Just minutes from local attractions like Margaret Harwell Art Museum, you'll appreciate the free WiFi, complimentary parking, and attentive staff that guests consistently praise.
The price is CNY637
CNY713 total
includes taxes & fees
May 17 - May 18
Hampton Inn Poplar Bluff
In-room safe, desk, free WiFi, bed sheets
Super 8 by Wyndham Poplar Bluff Missouri
Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (641 reviews)
This Missouri motel offers practical comforts with free WiFi, parking, and on-the-go breakfast daily. Just minutes from North Main Street Historic District and the art museum, it provides convenient access to local attractions.
The price is CNY405
CNY457 total
includes taxes & fees
Jun 7 - Jun 8
Super 8 by Wyndham Poplar Bluff Missouri
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (740 reviews)
Discover quiet comfort at this Poplar Bluff hotel with an indoor swimming pool and Italian restaurant. Near North Main Street Historic District, you'll enjoy helpful staff service, in-room refrigerators, and fitness facilities.
The price is CNY634
CNY716 total
includes taxes & fees
May 17 - May 18
Holiday Inn Poplar Bluff by IHG
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (893 reviews)
Situated near Poplar Bluff Station, this hotel offers both convenience and comfort with its 24-hour fitness center and refreshing indoor pool. Explore nearby North Main Street Historic District after enjoying the free breakfast and WiFi.
The price is CNY688
CNY777 total
includes taxes & fees
May 10 - May 11
Fairfield Inn & Suites by Marriott Poplar Bluff
Coffee service
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very Good, (1,003 reviews)
This budget-friendly motel offers free WiFi and parking with clean rooms appreciated by travelers. Helpful staff provide 24-hour service while the convenient location puts you near cultural attractions like the Margaret Harwell Art Museum.
The price is CNY442
CNY495 total
includes taxes & fees
May 13 - May 14
Motel 6 Poplar Bluff, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Learn more about Puxico

Puxico is well-known for its attractions such as Mark Twain National Forest and Mingo Wilderness.

See all hotels in Puxico
Photo by Mike McClain
Open Photo by Mike McClain

Check out reviews of Puxico hotels guests love

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

8/10 Good
"Clean and basic "
John W Van 1-night trip
Posted 7 hours ago
Motel 6 Poplar Bluff, MO

Frequently asked questions

How much does a hotel room cost in Puxico?
You can find top hotels in Puxico from CNY389 with options to suit your budget and needs. If you're looking for an affordable hotel in Puxico that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Puxico hotels?
Discover great deals on Puxico hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Puxico hotels.
Can I book Puxico hotels with free cancellation?
To book a refundable Puxico hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What hotels do travelers like in Puxico?
Guests like 'the Lakehouse' Lovely Wappapello Country Home!.
Can I book a refundable accommodation in Puxico?
If you want the flexibility to change your travel plans to Puxico, most accommodations provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Puxico be like during my visit?
The warmest months in Puxico are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and May.
Why should I book my Puxico hotel through Hotels.com?
There are plenty of reasons to book your Puxico travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.