Hotels in Potrero

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Where to stay in Potrero?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Potrero on Hotels.com. These Potrero hotels consistently deliver on quality, location and traveler experience. Last updated on September 29, 2026.

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

A building entrance with a covered walkway, glass doors, and palm trees.

A hotel room with two beds, a wooden headboard, a geometric wall art piece, and a patterned carpet.

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

CNY920

CNY1,046 total

includes taxes & fees

Oct 27 - Oct 28

A modern bar area with a checkered tile backsplash, bar stools, a central bar counter, and a decorative light fixture.

A luxurious lounge with leather sofas, a fireplace, bookshelves, and a chandelier.

2. Jamul Casino Resort

Jamul

CNY1,269

CNY1,399 total

includes taxes & fees

Oct 8 - Oct 9

A multi-story hotel with a modern design, featuring a central courtyard with palm trees and a well-lit entrance.

A modern lobby with a stone wall, a fireplace, and contemporary furniture.

A modern hotel lobby with a reception area, seating, and a fireplace.

An outdoor patio area with wicker furniture, a bar, and a pool.

3. Viejas Casino & Willows Hotel

Alpine

CNY722

CNY913 total

includes taxes & fees

Sep 30 - Oct 1

A hotel with a covered patio area featuring outdoor seating and a fire pit.

A restaurant with a wooden interior, granite countertops, and a flat-screen TV mounted on the wall.

A woman running on a treadmill in a gym with exercise equipment and a wall with informational posters.

A hotel with a stone facade, a covered entrance, and a sign that reads "AYRES."

4. Ayres Lodge Alpine

Alpine

CNY743

CNY804 total

includes taxes & fees

Oct 14 - Oct 15

A motel with a white facade, a red truck parked in front, and a staircase leading to the entrance.

A modern bathroom with a bathtub, toilet, and vanity.

A two-story motel with a red-tiled roof, a staircase leading to the upper floor, and a parking lot with a blue car.

A hotel room with two beds, a bedside table with a lamp, and a window with curtains.

5. Backcountry Inn Motel

Boulevard

CNY866

CNY935 total

includes taxes & fees

Sep 30 - Oct 1

A spacious lobby with a large seating area, a reception desk, and a television screen.

A multi-story hotel with a modern facade, a parking lot, and palm trees.

A laundry facility with multiple washing machines, a wooden bench, and a wall clock.

A modern kitchen with wooden cabinets, a black refrigerator, a microwave, a sink, and a coffee maker.

6. Element by Marriott San Diego Chula Vista

Otay Ranch

CNY1,262

CNY1,637 total

includes taxes & fees

Oct 30 - Oct 31

An outdoor seating area with fire pit, lounge chairs, and tables, adjacent to a building with large windows and a brick facade.

A modern hotel with a covered entrance, multiple floors, and a well-maintained garden area.

A spacious hotel lobby with a central bar area, comfortable seating, and a large window providing natural light.

A swimming pool with lounge chairs and umbrellas, a brick building with multiple windows, and a clear sky.

7. Hampton Inn Chula Vista Eastlake

Chula Vista

CNY1,095

CNY1,207 total

includes taxes & fees

Oct 11 - Oct 12

A swimming pool with palm trees and a mountain in the background.

A modern hotel with a prominent entrance, multiple floors, and a landscaped area with palm trees and a bridge.

A modern lounge area with leather seating, a central fire feature, and geometric patterned railings.

A modern lounge area with dark-toned seating, a central coffee table, and a stone accent wall.

8. Sycuan Casino Resort

El Cajon

CNY584

CNY723 total

includes taxes & fees

Oct 15 - Oct 16

A breakfast station with bread, bagels, waffles, and a coffee machine.

A hotel room with two beds, a desk, a chair, a television, and a painting on the wall.

A hotel with a sign reading "Quality Suites," featuring a parking lot with several cars, a covered parking structure, and palm trees.

A compact living space with a kitchenette, a sofa, a TV, and a lamp.

9. Quality Suites San Diego Otay Mesa

Otay Mesa

CNY697

CNY792 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with a flat-screen TV, a fireplace, and comfortable seating areas.

An outdoor patio with wicker furniture, a fire pit, and a grill area.

A modern dining area with a long table, chairs, a laptop, a plate of cookies, and a coffee cup.

A compact kitchen with a refrigerator, microwave, and dishwasher. There is a dining area with a table set for two, and a coffee maker on the counter.

10. Residence Inn by Marriott San Diego Chula Vista

Otay Ranch

CNY1,353

CNY1,491 total

includes taxes & fees

Oct 11 - Oct 12

A poolside area with lounge chairs and palm trees, overlooking a body of water.

A modern reception area with a wooden reception desk, a large artwork above it, and a snack bar in the background.

A modern bar area with wooden ceiling, bar stools, and a large window overlooking the city.

11. SpringHill Suites by Marriott Chula Vista Eastlake

Chula Vista

CNY1,264

CNY1,393 total

includes taxes & fees

Oct 11 - Oct 12

A garden with a gazebo, pathways, and a mountain in the background.

A building with a tiled roof, brick walls, and arched doorways. There are large planters and a palm tree in the foreground.

A cozy wooden room with a large bed, a small table, and a chair.

A clear swimming pool surrounded by a patio area with outdoor furniture, a building with a tiled roof, and palm trees.

12. Vineyard Hacienda

Jamul

CNY1,117

CNY1,206 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor seating area with fire pit, brick walls, and modern furniture.

A spacious living area with a large sofa, blue armchairs, a round coffee table, and a colorful abstract mural on the wall.

A hotel with a modern design, featuring a large sign for Homewood Suites by Hilton, multiple floors, and a welcoming entrance with a covered walkway.

13. Homewood Suites by Hilton Chula Vista-Eastlake

Chula Vista

CNY1,382

CNY1,523 total

includes taxes & fees

Oct 5 - Oct 6

An outdoor patio area with seating and a bar.

A spacious lobby with a modern design, featuring a large seating area, a reception desk, and large windows offering views of the city.

A modern hotel with a prominent sign reading "AYRES HOTEL".

A modern lounge area with two grey upholstered chairs, a small table, and a large window offering a view of palm trees and buildings.

14. Ayres Hotel San Diego South - Chula Vista

Otay Ranch

CNY1,263

CNY1,392 total

includes taxes & fees

Oct 12 - Oct 13

A reception area with a black counter, a potted plant, a white table, and a black office chair.

A Best In Suites hotel with a sign welcoming guests under new management.

A compact room with a bed, a desk with a computer and TV, a small refrigerator, and a trash bin.

15. Best Inn & Suites

El Cajon

CNY459

CNY505 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with two beds, a wooden headboard, bedside lamps, and artwork on the walls.

A living room with a blue sofa, a grey armchair, a coffee table, and a large plant.

A multi-story hotel with a red roof, a parking lot, and neatly trimmed trees.

A reception area with a counter, seating, and a potted plant.

16. Rancho San Diego Inn & Suites

El Cajon

CNY477

CNY525 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with a large bed, bedside tables with lamps, a flat-screen TV mounted on the wall, and a wooden floor.

A compact kitchen with a microwave, sink, and a small island counter.

A hotel room with a desk, chair, bed, TV, and curtains.

A multi-story motel with a central staircase and a parking lot.

17. Rodeway Inn El Cajon - San Diego East

El Cajon

CNY468

CNY515 total

includes taxes & fees

Oct 19 - Oct 20

View all properties

Go beyond your typical stay in Potrero

Pet friendly

Pool

Hot tub

Cottage

Check out reviews of Potrero hotels guests love

Ayres Lodge Alpine

10/10 Excellent

"Clean room comfortable beds. Choice of hot and cold breakfast"

Quality Suites San Diego Otay Mesa

10/10 Excellent

"Great service. Clean and spacious room. 100% recommend"

SpringHill Suites by Marriott Chula Vista Eastlake

8/10 Good

"The breakfast was already gone even only after 17 minutes after it started same as silverware."

Hampton Inn Chula Vista Eastlake

10/10 Excellent

"Such a nice, modern, spacious Hampton Inn! Very quiet location. Rooms were clean and spacious, breakfast was very good, and the concierge style text messaging from Ivan, came in handy. We had 3 issues (one about the WiFi, and two unrelated to the hotel) and we got prompt, courteous help! Staff was helpful in changing our itinerary, too. Gym was the best Hampton inn one I’ve experienced yet! Had one small issue, that being the finger tip towels weren’t refreshed after housekeeping. But nbd. I’d stay again."

Frequently asked questions

How much does a hotel room cost in Potrero?

You can discover great hotels in Potrero from CNY505 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Potrero that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Potrero hotels?

Discover great deals on Potrero hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Potrero hotels.

Can I book Potrero hotels with free cancellation?

In order to book a refundable Potrero hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Potrero?

If you're looking for hotels in central Potrero, check out Santuario Diegueño and Hotel Hacienda Santana. Travelers love Santuario Diegueño for its location, as well as the outdoor pool, restaurant and bar/lounge this hotel offers. Hotel Hacienda Santana is another popular central hotel with an indoor pool, a restaurant and a poolside bar.

Can I book refundable accommodations in Potrero?

If you want the flexibility to change your travel plans to Potrero, most hotels provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Potrero be like during my vacation?

The warmest months in Potrero are usually August and July with an average temp of 73°F. February and December are the chilliest months when the average temp is 53°F. The rainiest months are December and February.

Why should I book my Potrero accommodation with Hotels.com?

There are plenty of reasons to book your Potrero travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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