Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in La Mesa on Hotels.com. These La Mesa hotels consistently deliver on comfort, location and traveler experience. Last updated on .
Hotels in La Mesa
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Aug 25 - Aug 26Tomorrow
Aug 26 - Aug 27This weekend
Aug 28 - Aug 30Next weekend
Sep 4 - Sep 6Top 5 hotels in La Mesa at a glance
- 1. Best Western Plus La Mesa San Diego — 2.5-star hotel in La Mesa. Guest rating: 8.4/10 — Very Good.
- 2. Motel 6 La Mesa, CA - San Diego — 2-star hotel in La Mesa. Guest rating: 7.6/10 — Good.
- 3. Heritage Inn La Mesa — 2-star hotel in La Mesa. Guest rating: 7.0/10 — Good.
- 4. Motel 6 La Mesa, CA — 2-star hotel in La Mesa. Guest rating: 7.4/10 — Good.
- 5. Lamplighter Inn & Suites at SDSU — 2.5-star hotel in Mid-City. Guest rating: 9.0/10 — Wonderful.
Where to stay in La Mesa?
1. Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San DiegoLa Mesa
CNY908
CNY999 total
includes taxes & fees
Sep 13 - Sep 14
2. Motel 6 La Mesa, CA - San Diego
Motel 6 La Mesa, CA - San DiegoLa Mesa
CNY672
CNY740 total
includes taxes & fees
Aug 31 - Sep 1
3. Heritage Inn La Mesa
Heritage Inn La MesaLa Mesa
CNY511
CNY563 total
includes taxes & fees
Sep 2 - Sep 3
4. Motel 6 La Mesa, CA
Motel 6 La Mesa, CALa Mesa
CNY672
CNY740 total
includes taxes & fees
Aug 31 - Sep 1
5. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSUMid-City
CNY877
CNY989 total
includes taxes & fees
Sep 13 - Sep 14
6. Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San DiegoEl Cajon
CNY450
CNY515 total
includes taxes & fees
Aug 31 - Sep 1
7. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway HotelNational City
CNY962
CNY1,060 total
includes taxes & fees
Sep 7 - Sep 8
8. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego SouthChula Vista
CNY752
CNY828 total
includes taxes & fees
Sep 7 - Sep 8
9. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula VistaChula Vista
CNY703
CNY773 total
includes taxes & fees
Sep 7 - Sep 8
10. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula VistaOtay Ranch
CNY1,174
CNY1,293 total
includes taxes & fees
Sep 7 - Sep 8
11. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHGChula Vista
CNY920
CNY1,012 total
includes taxes & fees
Sep 7 - Sep 8
12. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista EastlakeChula Vista
CNY1,439
CNY1,586 total
includes taxes & fees
Sep 7 - Sep 8
13. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty StationSan Diego
CNY1,097
CNY1,261 total
includes taxes & fees
Sep 1 - Sep 2
14. DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission ValleyMission Valley
CNY932
CNY1,071 total
includes taxes & fees
Sep 7 - Sep 8
15. Best Western Seven Seas
Best Western Seven SeasMission Valley
CNY569
CNY654 total
includes taxes & fees
Sep 9 - Sep 10
16. Sycuan Casino Resort
Sycuan Casino ResortEl Cajon
CNY834
CNY998 total
includes taxes & fees
Sep 1 - Sep 2
17. Kings Inn San Diego
Kings Inn San DiegoMission Valley
CNY618
CNY709 total
includes taxes & fees
Sep 23 - Sep 24
18. Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp QuarterDowntown San Diego
CNY1,023
CNY1,186 total
includes taxes & fees
Aug 31 - Sep 1
19. Handlery Hotel
Handlery HotelMission Valley
CNY801
CNY921 total
includes taxes & fees
Sep 13 - Sep 14
20. Ayres Lodge Alpine
Ayres Lodge AlpineAlpine
CNY679
CNY735 total
includes taxes & fees
Sep 9 - Sep 10
Go beyond your typical stay in La Mesa
Pet friendly
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Family friendly
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Our prices for hotels in La Mesa are cheapest in February
Our prices for hotels in La Mesa are cheapest in February
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
Top neighborhoods in La Mesa
Casa de Oro-Mount Helix
La Mesa's Casa de Oro-Mount Helix neighborhood offers attractions including Mount Helix Park.
Mount Helix
The Mount Helix neighborhood offers attractions such as Mount Helix Park and FAITH CHAPEL.
Top landmarks in La Mesa
Mount Helix Park
7.4/10 (59 reviews)
If you're planning a bit of sightseeing head to Mount Helix Park— just one of the monuments in Casa de Oro-Mount Helix. Why not take a stroll along the port and watch the sunset while you're here? La Mesa has other landmarks you might want to visit such as Hotel del Coronado.
Computer Museum of America
6.6/10 (36 reviews)
Computer Museum of America is 1 mi (1.6 km) from central La Mesa, why not stop by during your stay. Hotels.com travelers also say the area is walkable and has lots of nice beaches. If you want to experience more of the culture La Mesa has to offer, head to San Diego State University, Sharp Grossmont Hospital, and Cal Coast Credit Union Open Air Theater.
La Mesa Memorial Fine Arts Center
La Mesa Memorial Fine Arts Center is in the heart of La Mesa, so why not stop by during your stay. If you have fun at La Mesa Memorial Fine Arts Center, you'll love Computer Museum of America, located nearby.
The Bancroft
If you find yourself in Mount Helix, you can stop off for a few drinks or snacks at The Bancroft.
Learn more about La Mesa
Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.
See all hotels in La Mesa
Check out reviews of La Mesa hotels guests love
Hard Rock Hotel San Diego
10/10 Excellent
"Excellent location!"
Wyndham San Diego Bayside
10/10 Excellent
"Wonderful stay on the bay! Very friendly staff, enjoyed the view from our balcony."
Omni San Diego Hotel at the Ballpark
10/10 Excellent
"Great stay all around!"
Bahia Resort Hotel
10/10 Excellent
"Very much enjoyed our stay! Bed was very comfortable. Well managed property!"
The Sofia Hotel
10/10 Excellent
"location is super, staff was friendly"
Paradise Point Resort & Spa
10/10 Excellent
"We love the charm of the hotel. Lots of walking paths and scenic routes right next to the beach."
Gaylord Pacific Resort & Convention Center
8/10 Good
"clean room"
Hotel del Coronado, Curio Collection by Hilton
10/10 Excellent
"The Del is such a wonderful place to stay. For the price you are really paying for the location and property amenities. The room itself doesn’t seem to match the price but is definitely nice enough. I will definitely stay at the Del again. The restaurants, beachfront property, and overall vibe made for a magical stay!"
The Dana on Mission Bay
10/10 Excellent
"This trip was meant a lot to me and my family. We didn’t come for a vacation but to honor and celebrate my husband who passed away. Our great experience at the created a space for our family to share, celebrate, and heal. Thank you to the staff for the clean room and hospitality."
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