Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover small-town Americana at its finest with a visit to the DeMoulin Museum's quirky collection. Catch a movie at the historic Globe Theater, where popcorn and nostalgia are always on the menu.
"This was a great hotel experience. The location was perfect as we had quick access to and from Route 70. The staff was extremely friendly and very helpful and responsive when we had an issue with our shower. The breakfast [according to my husband!] was phenomenal. Would definitely recommend this hotel."
"Impressive economy hotel!! Very very clean. The staff is personable, efficient and down right exceptional! Very well run hotel. Little perks along the way, water and cookies at check in, nice view from the back of the hotel, allowed a late check out."
Quality Inn & Suites Vandalia near I-70 and Hwy 51
10/10 Excellent
"I arrived about an hour before check in time hoping to check in early. There was nobody manning the front desk. I waited about 5 minutes, still nobody so I left and came back. When I did finally check in, the staff was very nice and accommodating and check in was easy. Anytime during my stay that I encountered staff they were all awesome.
The rooms looked like they were newly remodeled and were very nice. Everything worked and was very clean. The bed was comfortable. There was an ice machine and vending close by.
I was assigned a room close to a stairway. Since the rooms open to the outside, the first night was a bit noisy with people running up and down the stairs. The second night was not bad.
The pool was closed, kinda sad since it was 88 degrees and a major heat wave was starting. The grounds around the pool area could use some attention or an upgrade.
All in all, it was a good stay and I would stay there again. "
"Quiet, clean, great air conditioner in the room. Staff very friendly. Missed breakfast, would have been nice if coffee and packaged goods were avaliable until 10a. Will definitely stay again when traveling thru. "
"Place was nice and employees friendly. There is a train track not far away that blew the horn quite a bit, including overnight. Probably would stay somewhere a bit further away next time travelling that way. Hotel itself was fine. "
If you want the flexibility to change your plans to Greenville, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I stay in Greenville if I'm looking for a cheap accommodation?
What will the weather in Greenville be like during my vacation?
July and August are typically the warmest months in Greenville when the average temp is 74°F. January and February are the coldest months when the average temperature is 36°F. April and May are the months with the most rain.
Why should I book my Greenville hotel through Hotels.com?
There are lots of reasons to book your Greenville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.
Find out more about Greenville
Find out more about Greenville
Greenville is a family-friendly city where you can spend time checking out the local cuisine. Simply book an excursion to enjoy your stay a little more. Why not take time to see places like Greenville Country Club and Patriot's Park? You may want to expand your exploration to the surrounding area to see Copper Dock Winery and other sights.
