Hotels in Seneca

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Check prices for these dates

Tonight
Dec 24 - Dec 25
Tomorrow
Dec 25 - Dec 26
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Where to stay in Seneca?

Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123
2.5 star property
8.0 out of 10, Very Good, (665)
The price is CNY517
CNY611 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn Seneca Clemson Area US-123
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Seneca and vicinity

Reception
Quality Inn Clemson near University

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (892)
The price is CNY353
CNY392 total
includes taxes & fees
Dec 30 - Dec 31
Quality Inn Clemson near University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out hotels with a pool in Seneca

Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (665)
The price is CNY517
CNY611 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn Seneca Clemson Area US-123
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You may also like pet-friendly hotels in Seneca

Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (51)
The price is CNY626
CNY997 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Seneca?

Our prices for hotels in Seneca are cheapest in December
Price trends for hotels in Seneca
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Seneca
December
Low crowds
High 12°C / low 4°C. Sunny most days.
View properties in December
12°
weather_sun
December, Low crowds, average high temperature 12 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
4°
10°
weather_partly_sunny
January, Low crowds, average high temperature 10 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
1°
13°
weather_partly_sunny
February, Low crowds, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
3°
17°
weather_sun
March, Moderate crowds, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
22°
weather_sun
April, Moderate crowds, average high temperature 22 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
26°
weather_sun
May, Moderate crowds, average high temperature 26 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
31°
weather_sun
June, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
32°
weather_sun
July, High crowds, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
31°
weather_sun
August, High crowds, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
28°
weather_sun
September, High crowds, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
23°
weather_sun
October, High crowds, average high temperature 23 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
12°
17°
weather_sun
November, Low crowds, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
Monthly weather averages (˚C)

Top neighborhoods in Seneca

Downtown

Seneca's Downtown neighborhood has a host of places to visit such as Seneca Historic District and Oconee County Library Seneca Branch.

Serenity Bay

Seneca's Serenity Bay neighborhood offers attractions including Lake Keowee.

Pine Ridge Point

Seneca's Pine Ridge Point neighborhood offers attractions including Lake Keowee.

Indian Oaks

Seneca's Indian Oaks neighborhood offers attractions including Lake Keowee.

Keowee Plantation

Seneca's Keowee Plantation neighborhood offers attractions including Lake Keowee.

Top landmarks in Seneca

Lovely shot of the Blue Ridge Mountains in the distance, with a rural pasture in the foreground, in late summer when the grass is starting to turn yellow and brown. Upstate South Carolina scene.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.
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High Shoals Falls in South Mountains State Park

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.
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Learn more about Seneca

Seneca, well-known for its sports and university life, features attractions such as Keowee Reservoir and Lake Keowee. This family-friendly city has something for everyone including its waterfront, coffeehouses, and sights like Keowee Key Golf Course and Lake Hartwell.

See all hotels in Seneca
Lake Keowee South Carolina

Check out reviews of Seneca hotels guests love

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent
"Clean rooms, friendly staff, great game room/hang out space. "
karen 2-night trip
Posted 4 days ago
Tru by Hilton Seneca Clemson

Frequently asked questions

How much does a hotel room cost in Seneca?
You can find top hotels in Seneca from CNY559 with options to suit your budget and needs. If you're after an affordable hotel in Seneca that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at Seneca hotels?
Discover great deals on Seneca hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. And make sure to check out our last-minute deals on Seneca hotels.
Can I book Seneca hotels with free cancellation?
It's easy to book a refundable Seneca hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some of the best Seneca hotels with free parking?
If you're exploring by car, finding a great Seneca hotel with free parking is a win. Our travelers' favorites include:
What accommodations do travelers like in Seneca?
Tru by Hilton Seneca Clemson, Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area are all properties that our guests really like.
Can I book refundable accommodations in Seneca?
If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a budget-friendly accommodation?
Quality Inn Seneca Clemson Area US-123, Lakeside Lodge Clemson and Best Western Seneca-Clemson are a few accommodations you might want to consider that'll save you money.
Where can I stay in Seneca if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 199 vacation homes. In addition, there are 13 apartments and 12 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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