Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
"Excellent location. Super nice to have guest laundry, microwave, etc. Wonderful restaurants all around. Indoor pool and exercise room make this a great pick. Would recommend!"
"This hotel was very nice. Clean, comfortable, spacious rooms, free breakfast, happy hour. I did not like the parking and hotel is beside functioning train tracks. "
"The room was very clean. The cleaning staff made origami designs from the towels which were fun. The breakfast was really good. And the staff that we interacted with were very nice and polite"
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
10/10 Excellent
"Bed was comfy, onsite free parking was awesome, room very clean and updated, staff friendly and delicious continental breakfast. We will definitely stay here again!"
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
10/10 Excellent
"Great breakfast 😋 This hotel is GREAT. Everything is nice and wheelchair friendly. I especially love the warm pool and hot tub. Half the price of hotels in the same area, yet twice as nice. Stay here often. Hair dryers, ironing boards, coffee pot, fridge, microwave...all in your room. If you forget a toiletry item, they supply it free."
If you're looking for the flexibility to change your plans to Wykoff, most accommodations offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Wykoff be like during my visit?
The warmest months in Wykoff are usually July and August with an average temp of 68°F. January and February are the chilliest months when the average temp is 22°F. The rainiest months are June and May.
Why should I book my Wykoff hotel through Hotels.com?
There are plenty of reasons to book your Wykoff travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.
Find out more about Wykoff
Find out more about Wykoff
If you're looking to discover somewhere new, look no further than Wykoff. Whether you're planning to stay for a night or for the week, the area around Wykoff has accommodations to fit every need. Search for hotels in Wykoff with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Wykoff hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Wykoff hotel deals are here with our lowest price guarantee.