Hotels in Tuscola

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Where to stay in Tuscola?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Tuscola on Hotels.com. These Tuscola hotels consistently deliver on quality, location and traveler experience. Last updated on September 15, 2026.

1. Comfort Inn & Suites Regional Medical Center

Abilene

CNY1,074

CNY1,235 total

includes taxes & fees

Sep 20 - Sep 21

2. Hilton Garden Inn Abilene

Park Central Area

CNY1,375

CNY1,581 total

includes taxes & fees

Sep 20 - Sep 21

3. Abilene Whitten Inn

Park Central Area

CNY1,241

CNY1,427 total

includes taxes & fees

Sep 15 - Sep 16

Studio Suite, 1 King Bed with Sofa bed, Kitchenette

4. Home2 Suites by Hilton Abilene Southwest

Park Central Area

CNY1,413

CNY1,625 total

includes taxes & fees

Sep 20 - Sep 21

5. TownePlace Suites by Marriott Abilene Southwest

Park Central Area

CNY1,717

CNY2,003 total

includes taxes & fees

Oct 9 - Oct 10

6. MCM Elegante Suites Abilene

Park Central Area

CNY1,362

CNY1,566 total

includes taxes & fees

Oct 4 - Oct 5

7. Holiday Inn Express & Suites Abilene by IHG

Park Central Area

CNY1,207

CNY1,389 total

includes taxes & fees

Sep 20 - Sep 21

8. Hampton Inn Abilene

Park Central Area

CNY1,036

CNY1,191 total

includes taxes & fees

Sep 20 - Sep 21

9. Days Inn by Wyndham Abilene

Park Central Area

CNY656

CNY754 total

includes taxes & fees

Sep 20 - Sep 21

Room, 2 Queen Beds, Accessible, Non Smoking (Mobility/Hearing, Tub w/ Grab Bars)

10. La Quinta Inn & Suites by Wyndham Abilene Mall

Park Central Area

CNY977

CNY1,123 total

includes taxes & fees

Sep 20 - Sep 21

11. Doubletree by Hilton Abilene Downtown Convention Center

Downtown Abilene

CNY1,414

CNY1,626 total

includes taxes & fees

Oct 4 - Oct 5

Standard Room, 2 Queen Beds, Non Smoking

12. Big Country Hotel & Suites, SureStay Collection by BW

Park Central Area

CNY1,117

CNY1,284 total

includes taxes & fees

Sep 20 - Sep 21

Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking

13. Comfort Suites University

Abilene

CNY1,050

CNY1,208 total

includes taxes & fees

Sep 20 - Sep 21

14. Courtyard by Marriott Abilene Southwest/Abilene Mall South

Park Central Area

CNY1,078

CNY1,266 total

includes taxes & fees

Sep 20 - Sep 21

15. Home2 Suites by Hilton Abilene

Abilene

CNY1,568

CNY1,814 total

includes taxes & fees

Sep 20 - Sep 21

16. Fairfield Inn & Suites Abilene

Park Central Area

CNY1,111

CNY1,303 total

includes taxes & fees

Sep 27 - Sep 28

Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave

17. Best Western Abilene Inn & Suites

Abilene

CNY1,111

CNY1,277 total

includes taxes & fees

Sep 20 - Sep 21

18. Hampton Inn & Suites Abilene I-20

Abilene

CNY1,425

CNY1,639 total

includes taxes & fees

Oct 11 - Oct 12

19. TownePlace Suites by Marriott Abilene Northeast

Abilene

CNY1,503

CNY1,743 total

includes taxes & fees

Sep 27 - Sep 28

20. Cobblestone Inn & Suites - Winters

Winters

View all properties

Go beyond your typical stay in Tuscola

Top landmarks in Tuscola

Abilene State Park

7.8/10 (26 reviews)

Abilene State Park is 4.8 mi (7.8 km) from central Tuscola, why not stop by during your stay.

See properties

Check out reviews of Tuscola hotels guests love

Comfort Inn & Suites Regional Medical Center

Abilene

10/10 Exceptional

Mary

Home2 Suites by Hilton Abilene

Abilene

10/10 Exceptional

Kenneth

Big Country Hotel & Suites, SureStay Collection by BW

Park Central Area

10/10 Exceptional

Dominic

Holiday Inn Abilene - North College Area by IHG

Abilene

10/10 Exceptional

Anonymous traveler

We liked this Courtyard by Marriott the best of the several hotels we have stayed at in Abilene. All the staff were very friendly and especially helpful. Although it was very busy with a visiting out of town soccer team, it was quiet throughout. The party room is well sound insulated; the only indication that there was a party was when the door was opened occasionally. Karaoke, you gotta love it! It was a little disconcerting to see a $60 charge listed as "processing" for 3 days after...

WI-Mart

TownePlace Suites by Marriott Abilene Northeast

Abilene

10/10 Exceptional

Noyy

Frequently Asked Questions

How much does a hotel room cost in Tuscola?

You can choose a great hotel in Tuscola from CNY504 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Tuscola that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.

How can I find deals and earn rewards at Tuscola hotels?

Discover great deals on Tuscola hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. And make sure to check out our last-minute deals on Tuscola hotels.

Can I book Tuscola hotels with free cancellation?

To book a refundable Tuscola hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

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