Hotels in Santa Ana

Q: Can I receive a refund if I cancel my Santa Ana hotel booking?

The majority of hotels offer free cancellation , so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".

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Dates

April 2026

May 2026

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Where to stay in Santa Ana?

Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers

Casco View Apartments

Santa Ana

CNY864 total

includes taxes & fees

Mar 30 - Mar 31

Apartment (20) | Iron/ironing board, free WiFi, bed sheets

La Manzana by Wynwood House

Santa Ana

CNY813 total

includes taxes & fees

Apr 7 - Apr 8

Hostal La Cigarra

Santa Ana

CNY218 total

includes taxes & fees

Apr 6 - Apr 7

ART CASCO The Hotel

Santa Ana

CNY280 total

includes taxes & fees

Apr 27 - Apr 28

Hotel República

Santa Ana

CNY222 total

includes taxes & fees

Mar 29 - Mar 30

Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

21.1 km from Santa Ana

CNY965 total

includes taxes & fees

Apr 27 - Apr 28

ORHO HOTEL BOUTIQUE PANAMA Airport

20.5 km from Santa Ana

CNY1,076 total

includes taxes & fees

Apr 2 - Apr 3

Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas

Riande Aeropuerto Hotel & Casino

19.8 km from Santa Ana

CNY951 total

includes taxes & fees

Mar 29 - Mar 30

Courtyard by Marriott Panama Metromall

14.7 km from Santa Ana

CNY834 total

includes taxes & fees

Apr 26 - Apr 27

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz, 12.7 km from Santa Ana

CNY1,893 total

includes taxes & fees

Apr 5 - Apr 6

Arcadia Condo Suites

Costa del Este, 10.2 km from Santa Ana

CNY1,125 total

includes taxes & fees

Apr 10 - Apr 11

The Westin Panama

Costa del Este, 9.4 km from Santa Ana

CNY1,563 total

includes taxes & fees

Apr 5 - Apr 6

Daily buffet breakfast (PAB 21 per person)

Sheraton Grand Panama

San Francisco, 5.7 km from Santa Ana

CNY1,061 total

includes taxes & fees

Apr 4 - Apr 5

Aloft Panama

San Francisco, 5.7 km from Santa Ana

CNY903 total

includes taxes & fees

Apr 4 - Apr 5

4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

Punta Pacifica, 4.3 km from Santa Ana

CNY2,045 total

includes taxes & fees

Apr 5 - Apr 6

Breakfast, lunch, dinner served; international cuisine

Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco, 5.1 km from Santa Ana

CNY698 total

includes taxes & fees

Apr 1 - Apr 2

Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

Punta Paitilla, 4 km from Santa Ana

CNY1,545 total

includes taxes & fees

Apr 19 - Apr 20

Plaza Paitilla Inn Hotel

Punta Paitilla, 3.4 km from Santa Ana

CNY917 total

includes taxes & fees

Apr 23 - Apr 24

Courtyard by Marriott Panama Multiplaza Mall

San Francisco, 4.5 km from Santa Ana

CNY769 total

includes taxes & fees

Apr 18 - Apr 19

Las Americas Golden Tower Panama

Punta Paitilla, 3.6 km from Santa Ana

CNY1,245 total

includes taxes & fees

Apr 12 - Apr 13

View all properties

Compare popular hotels in Santa Ana

Property	Property class	Guest rating
Casco View Apartments	3.5 star property	9.0 Wonderful 82 reviews	View
Hostal La Cigarra	2.0 star property	7.6 Good 65 reviews	View
La Manzana by Wynwood House	3.0 star property	7.2 Good 15 reviews	View
Hotel República	2.0 star property	6.6 188 reviews	View
ART CASCO The Hotel	2.0 star property	6.0 11 reviews	View

Top landmarks in Santa Ana

El Machetazo Santa Ana

If you want to give your credit card some exercise, head out to El Machetazo Santa Ana in Santa Ana. Splash some more cash at Avenida Central and Paseo de Las Bovedas.

See properties

Check out reviews of Santa Ana hotels guests love

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

8/10 Good

"Breakfast was good lots of choices, friendly staff and walkable "

Principe Hotel and Suites

10/10 Excellent

"Thank you for the nice stay. We’re looking forward to returning this weekend. This will be easy as our go-to place when traveling through Panama City for overnights. Thanks for a decent room at a reasonable price. Breakfast is not in the hotel but a 30 foot walk to next door. Just for those expecting that to be in the hotel, it’s only available next door and give yourself some time to get it as the service is a bit slower for hot meals."

Casco View Apartments

6/10 Okay

"We had an issue with the hot water and good that there’s a washer but no dryer. Also, the description of the apartments is great, but didn’t have information on where, what type of neighborhood it’s located. Also, pull out couch is not really a bed and lack more bed sheets and towels for the amount of people staying. Had two issues, AC and bedroom light in room broke but was repaired quickly. "

Frequently asked questions

Is Santa Ana expensive to stay in?

You can find great hotels from CNY218 in Santa Ana to suit a range of budgets. If you're looking for an affordable stay in Santa Ana, Hostal La Cigarra is a great low-cost option. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".

How can I find discounted rates and deals for Santa Ana hotels?

Discover great deals on hotels in Santa Ana with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santa Ana hotels.

Can I receive a refund if I cancel my Santa Ana hotel booking?

The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Santa Ana hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".

Is it worth staying in Santa Ana?

You're spoilt for choice with 115 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Santa Ana makes it easy to explore Panama City, including the neighborhoods of Casco Viejo and Bella Vista.

Find out more about Santa Ana

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